Ayurveda and the science of aging

Rao, Rammohan V.

doi:10.1016/j.jaim.2017.10.002

Cited by 42 publications

(18 citation statements)

References 99 publications

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“…The abovementioned study design is similar to our therapeutic program for people with SCI and MCI, where Bm is administered in combination with other nutraceuticals and cogniceuticals [ 15 , 111 ].…”

Section: Introductionmentioning

confidence: 99%

Neuroprotective Herbs for the Management of Alzheimer’s Disease

Gregory¹,

et al. 2021

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Background—Alzheimer’s disease (AD) is a multifactorial, progressive, neurodegenerative disease that is characterized by memory loss, personality changes, and a decline in cognitive function. While the exact cause of AD is still unclear, recent studies point to lifestyle, diet, environmental, and genetic factors as contributors to disease progression. The pharmaceutical approaches developed to date do not alter disease progression. More than two hundred promising drug candidates have failed clinical trials in the past decade, suggesting that the disease and its causes may be highly complex. Medicinal plants and herbal remedies are now gaining more interest as complementary and alternative interventions and are a valuable source for developing drug candidates for AD. Indeed, several scientific studies have described the use of various medicinal plants and their principal phytochemicals for the treatment of AD. This article reviews a subset of herbs for their anti-inflammatory, antioxidant, and cognitive-enhancing effects. Methods—This article systematically reviews recent studies that have investigated the role of neuroprotective herbs and their bioactive compounds for dementia associated with Alzheimer’s disease and pre-Alzheimer’s disease. PubMed Central, Scopus, and Google Scholar databases of articles were collected, and abstracts were reviewed for relevance to the subject matter. Conclusions—Medicinal plants have great potential as part of an overall program in the prevention and treatment of cognitive decline associated with AD. It is hoped that these medicinal plants can be used in drug discovery programs for identifying safe and efficacious small molecules for AD.

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Section: Introductionmentioning

confidence: 99%

Neuroprotective Herbs for the Management of Alzheimer’s Disease

Gregory¹,

et al. 2021

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“…Aging is found associated with several disease conditions and characterized by a gradual functional decline posing a significant risk for neurodegenerative diseases, cancers, cardiovascular diseases, and diabetes [18]. Ayurveda considered aging as an important health context since ancient times [19]. It is referred to as "Jara" (aging or declining phase) in classical Ayurveda.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and Tolerability of Ashwagandha Root Extract in the Elderly for Improvement of General Well-being and Sleep: A Prospective, Randomized, Double-blind, Placebo-controlled Study

Kelgane¹,

Salve²,

Sampara³

et al. 2020

Cureus

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Background Ashwagandha is an excellent adaptogen that is being used since ancient times in Ayurvedic medicine. Traditionally, it is used for various ailments and general well-being, including the treatment of geriatric patients. Managing quality of life (QoL) remains a challenge for the elderly population, especially joint pain management, sleep, and general well-being. With a growing global elderly population, QoL management with efficient medication and supplementation is the major healthcare requirement. Objective The objective of this study was to assess the safety, efficacy, and tolerability of Ashwagandha (Withania somnifera (L.) Dunal.) root extract on the improvement of general health and sleep in elderly people. Methods This 12-week, prospective, randomized, double-blind, placebo-controlled study was conducted on individuals of either gender aged between 65-80 years. Participants were randomized to receive Ashwagandha root extract at a dose of 600 mg/day (n = 25) orally, or identical placebo capsules with the same dose (n = 25) for 12 weeks. Efficacy was assessed using the WHOQOL-BREF questionnaire, sleep quality, mental alertness on rising, and Physician's Global Assessment of Efficacy to Therapy (PGAET). The safety and tolerability were assessed using the clinical adverse events reporting and Patient's Global Assessment of Tolerability to Therapy (PGATT).

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“…A number of studies were reported from different healthcare disciplines regarding prevention of COVID-19 [30][31][32][33][34].…”

Section: Recommendation For Ayush Initiativesmentioning

confidence: 99%

Preventive Measures to Conquest COVID-19: A Mini-review

Sawarkar

2021

JPRI

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Ayurveda is the bunch of blooms having multiple spectrums to prevent health and immune to fight with present and future trends of viruses. The principles of Ayurveda make life span extensive and healthy. COVID-19 is the todays crisis situation, world wide people are in dread to respiratory disease symptoms as primary indicators of corona virus. So, Ayurveda literature have the various remedies to strengthening respiratory system with preventive measures like Pranayama, Yoga, Meditation, Good sleep, Diet, Lifestyle and Medication. Prevention is the need of the time to fight with COVID-19 because there is no treatment and vaccines till date.

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Ayurveda and the science of aging

Cited by 42 publications

References 99 publications

Neuroprotective Herbs for the Management of Alzheimer’s Disease

Neuroprotective Herbs for the Management of Alzheimer’s Disease

Efficacy and Tolerability of Ashwagandha Root Extract in the Elderly for Improvement of General Well-being and Sleep: A Prospective, Randomized, Double-blind, Placebo-controlled Study

Preventive Measures to Conquest COVID-19: A Mini-review

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