<b>Antibiotic Production as a Typing Tool for the Dermatophytes</b>

Hammadi, Kheira; Howell, S. A.; Noble, W. C.

doi:10.1111/j.1439-0507.1988.tb04405.x

Cited by 4 publications

(6 citation statements)

References 10 publications

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“…However, the two species of T. mentagrophytes (S2 and S4) gave two unknown compounds, which do not match with Betina classification (Betina, 1973) of the thin layer antibiotic analysis (results not shown). The work done before by Hammadi et al (1988) on the same species showed the production of penicillin-like substances by the same species, the only differences for the work before is the temperature of incubation. For the previous work, the incubation temperature was 30 o C, however the temperature of the present work is 32 o C. Therefore, it can be deduced that incubation temperature has an effect on secondary metabolites production during the fermentation (Youssef et al, 1979).…”

Section: Resultsmentioning

confidence: 92%

“…Antibacterial screening of dermatophytic fungi metabolites. Days S1 S2 S3 S4 S5 S6 S7 S8 S9 S10 1 0 0 0 0 0 0 0 0 0 0 2 Hammadi et al, 1988) and incubated at 30°C in an orbital incubator at 140 rpm. After 10 days of incubation, the growth media was extracted with an equal volume of acetone.…”

Section: Methodsmentioning

confidence: 99%

“…(Peck et al, 1945), fusidic acid and closely related compounds, azalomycin-like antibiotics, actinomycin-like antibiotic and ranges of compounds fusidanes (Ryall et al, 1980). Further observations on trichophytic isolates of dermatophytes (Hammadi et al, 1988) showed that T. rubrum and T. mentagrophytes produced a streptomycin-like and azalomycin-like compound and other unidentifiables.…”

Section: Dermatophytes Fungi Have Long Been Known To Produce Antibactmentioning

confidence: 96%

“…The ability of dermatophytes to produce penicillin-like substances in vitro has been reported by several authors, (Uri et al, 1957;Youssef et al, 1978;Hammadi et al, 1988). Antibiotic production by dermatophytes was first investigated by Nakumura (1932) who discovered antibacterial activity in the Trichophyton species.…”

Section: Dermatophytes Fungi Have Long Been Known To Produce Antibactmentioning

confidence: 98%

“…Antibiotic production by dermatophytes was first investigated by Nakumura (1932) who discovered antibacterial activity in the Trichophyton species. Further observations were made by Honda in 1936 (cited by Hammadi et al, 1988). However, the classification of antibiotic type was made by Lapin-scott (1987) who thought dermatophytes produced a penicillin-like substance based on observations of activity against bacteria.…”

Section: Dermatophytes Fungi Have Long Been Known To Produce Antibactmentioning

confidence: 99%

See 4 more Smart Citations

Antibiotic like-substances produced by some trichophytic dermatophytes

Hammadi¹,

D²,

Selselet³

et al. 2007

Afr. J. Biotechnol.

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Antibiotic production by dermatophytic fungi was demonstrated. Among 10 anthropophilic dermatophytes strains tested for their ability to produce antibiotics, four were found to be producers. The outcome for a qualitative identification of the produced antibiotics reveals four types ; a penicillin-like substance produced by Trichophyton gourvillii, and two different types of unknown substances obtained from two strains of Trichophyton mentagrophytes var. interdigitales and the kojic acid-like antibiotic substance produced by Trichophyton verruccosum.

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Section: Resultsmentioning

confidence: 92%

Section: Methodsmentioning

confidence: 99%

Section: Dermatophytes Fungi Have Long Been Known To Produce Antibactmentioning

confidence: 96%

Section: Dermatophytes Fungi Have Long Been Known To Produce Antibactmentioning

confidence: 98%

Section: Dermatophytes Fungi Have Long Been Known To Produce Antibactmentioning

confidence: 99%

See 3 more Smart Citations

Antibiotic like-substances produced by some trichophytic dermatophytes

Hammadi¹,

D²,

Selselet³

et al. 2007

Afr. J. Biotechnol.

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Typing tools for the investigation of epidemic fungal infection

Howell

Noble

1990

Epidemiol. Infect.

Self Cite

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The epidemiology of bacterial infection is investigated by the use of identification procedures at a sub-species level by such techniques as serotyping, phage typing, various antigen recognition tests, plasmid profiling and DNA probes. Fungal epidemiology has tended to lag behind in the use of this technology, particularly with the filamentous fungi, though several techniques have been developed for yeasts and especially forCandida albicans. This review will briefly describe the application of these methods to outbreaks ofC. albicansinfection, describe the limited methods available for the investigation of filamentous fungal infection and indicate the necessity for increased research in this area.

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The dermatophytes

1995

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The etiologic agents of the dermatophytoses (ringworm) are classified in three anamorphic (asexual or imperfect) genera, Epidermophyton, Microsporum, and Trichophyton. Species capable of reproducing sexually belong in the teleomorphic genus, Arthroderma, of the Ascomycota. On the basis of primary habitat association, they may be grouped as geophilic (soil associated), zoophilic, and anthropophilic. Adaptation to growth on humans by most geophilic species resulted in diminished loss of sporulation, sexuality, and other soil-associated characteristics. The dermatophytes have the ability to invade keratinized tissue (skin, hair, and nails) but are usually restricted to the nonliving cornified layer of the epidermis because of their inability to penetrate viable tissue of an immunocompetent host. However, invasion does elicit a host response ranging from mild to severe. Acid proteinases, elastase, keratinases, and other proteinases reportedly act as virulence factors. The development of cell-mediated immunity correlated with delayed hypersensitivity and an inflammatory response is associated with clinical cure, whereas the lack of or a defective cell-mediated immunity predisposes the host to chronic or recurrent dermatophyte infection. Chronic dermatophytosis is mostly caused by Trichophyton rubrum, and there is some evidence that mannan produced by this fungus suppresses or diminishes the inflammatory response. Since dermatophytes cause a communicable disease, modes of transmission and control are discussed as well as a survey of recent trends in therapy. Collection of specimens, culture media, and tests for identification are also presented. Genetic studies have led to an understanding of incompatibility mechanisms, pleomorphism and variation, resistance to griseofulvin, and virulence. Molecular biology has contributed to our knowledge of the taxonomy and phylogenetic relationships of dermatophytes.

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Antibiotic Production as a Typing Tool for the Dermatophytes

Abstract: Summary: A typing scheme for dermatophytes, based on their antibiotic production, is proposed and evaluated. Zusammenfassung: Ein Typisierungsschema für Dermatophyten, das auf deren Antibiotika‐Produktion beruht, wird vorgeschlagen und bewertet.

Cited by 4 publications

References 10 publications

Antibiotic like-substances produced by some trichophytic dermatophytes

Antibiotic like-substances produced by some trichophytic dermatophytes

Typing tools for the investigation of epidemic fungal infection

The dermatophytes

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