<b>Der Bodymass-Index (BMI) hat keinen Einfluss auf die Häufigkeit von Refluxbeschwerden - Ergebnisse einer deutschlandweiten Aufklärungskampagne</b>

Madisch, Ahmed; Weihs, Ch; Schlaud, Martin; Heimann, David M.; Meyer, Harold; Hotz, James

doi:10.1055/s-2002-36464

Cited by 7 publications

(1 citation statement)

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“…For example, opposing effects of coffee or caffeine on GERD have been reported, 11,12 questions remain about the potential relationship between esophageal acid exposure and meal times, 13,14 as well as about whether GERD symptoms are related to body mass index (BMI). 15,16 Because it is difficult for patients who lack awareness of what constitutes a high-risk lifestyle to correct unhealthful habits after the emergence of red-flag symptoms before irreversible damage has been done, such patients tend to have poor drug treatment outcomes.…”

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confidence: 99%

Lifestyle intervention for gastroesophageal reflux disease: a national multicenter survey of lifestyle factor effects on gastroesophageal reflux disease in China

Yuan

Wang

et al. 2019

Therap Adv Gastroenterol

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Background: Poor habits can worsen gastroesophageal reflux disease (GERD) and reduce treatment efficacy. Few large-scale studies have examined lifestyle influences, particularly eating habits, on GERD in China, and research related to eating quickly, hyperphagia, and eating hot foods is quite limited. The aim of this study was to evaluate the relationship between GERD pathogenesis and lifestyle factors to produce useful information for the development of a clinical reference guide through a national multicenter survey in China. Methods: Symptom and lifestyle/habit questionnaires included 19 items were designed. The questionnaire results were subjected to correlation analysis relative to GERD symptom onset. A standard proton pump inhibitor (PPI) was advised to correct patients with unhealthful lifestyle habits. Results: A total of 1518 subjects (832 GERD, 686 non-GERD) enrolled from six Chinese hospitals completed symptom and lifestyle/habit questionnaires. The top lifestyle factors related to GERD were fast eating, eating beyond fullness, and preference for spicy food. Univariate analysis showed that 21 factors, including male gender, a supra-normal body mass index (BMI), smoking, drinking alcohol, fast eating, eating beyond fullness, eating very hot foods, and drinking soup, among others, were associated with GERD ( p < 0.05). Logistic multivariate regression analysis revealed the following risk factors for GERD [with odds ratios (ORs)]: fast eating (4.058), eating beyond fullness (2.849), wearing girdles or corsets (2.187), eating very hot foods (1.811), high BMI (1.805), lying down soon after eating (1.544), and smoking (1.521). Adjuvant lifestyle interventions improved outcomes over medication alone ( z = –8.578, p < 0.001 Mann–Whitney rank sum test). Conclusions: Lifestyle interventions can improve medication efficacy in GERD patients. Numerous habits, including fast eating, eating beyond fullness, and eating very hot foods, were associated with GERD pathogenesis. The present results may be useful as a reference for preventive education and treatment.

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