B-mode transorbital ultrasonography for the diagnosis of idiopathic intracranial hypertension: an updated systematic review and meta-analysis

Janitschke, Daniel; Stögbauer, Jakob; Lattanzi, Simona; Brigo, Francesco; Lochner, Piergiorgio

doi:10.1007/s10072-023-07016-z

Cited by 3 publications

(3 citation statements)

References 45 publications

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“…Bei funduskopischen Messungen wird ab einer Höhe von >0,6 mm (optic Disc Elevation; ODE) von einem Papillenödem ausgegangen [20]. Die sonografische Messung erfolgt zwischen dem Fundus und der Papillenkuppel in vergrößerter Darstellung.…”

Section: Papillenpathologie Bei Idiopathischer Intrakranieller Hypert...unclassified

Ultraschalldiagnostik peripherer Nerven und des Nervus opticus

Ceanga,

Günther,

Axer

2024

Neurologie up2date

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Section: Papillenpathologie Bei Idiopathischer Intrakranieller Hypert...unclassified

Ultraschalldiagnostik peripherer Nerven und des Nervus opticus

Ceanga,

Günther,

Axer

2024

Neurologie up2date

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“…In recent times, noninvasive techniques like transorbital sonography and Doppler have been explored to aid in diagnosing and monitoring patients with IIH. [ 2 ]…”

Section: Introductionmentioning

confidence: 99%

“…Ocular sonography, in the context of IIH, is primarily used to measure the diameter of the optic nerve sheath (ONSD). [ 2 ] It can also provide valuable insights into the real-time hemodynamic characteristics of the central retinal artery (CRA) and the ophthalmic artery (OA), such as peak systolic velocity, pulsatility index (PI) and resistance index (RI). [ 2 ]…”

Section: Introductionmentioning

confidence: 99%

Characterization of Ocular Sonography Findings and their Relationship to Clinical Features from a South Indian Cohort of Idiopathic Intracranial Hypertension

Kishore,

Patwardhan,

Aravinda

et al. 2024

Annals of Indian Academy of Neurology

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Background: Idiopathic intracranial hypertension (IIH) typically manifests with headache, accompanied by papilledema and visual loss, and has a higher prevalence in females. In recent years, ocular sonography, particularly, measurement of optic nerve sheath diameter (ONSD), is being investigated for diagnosis of IIH. Methods: A total of 35 patients over the age of 18 years, fulfilling the modified Dandy’s criteria for diagnosis of IIH were included. Patients underwent assessment with magnetic resonance imaging, lumbar puncture, and ocular sonography to measure ONSD and ocular arterial indices. Results: The mean ONSD values (in centimeters) in the right eye of patients with IIH was 0.57 ± 0.13, while it was 0.48 ± 0.03 in controls. In the left eye, the mean ONSD value (cm) was 0.59 ± 0.13 in patients with IIH and 0.48 ± 0.03 in controls. ONSD was significantly higher in cases compared to controls (P < 0.001, Welch test). Pulsatility index of the central retinal artery was significantly higher in cases compared to controls (P < 0.001, Welch test). Resistance index of the ophthalmic artery was statistically significant (P < 0.005, Welch test). Receiver operating characteristic curve analysis revealed a cutoff value of 5.1 mm on the right side and 5 mm on the left side had a sensitivity and specificity of more than 80% for IIH diagnosis. Conclusion: Our study provides insights into the utility of optic nerve sheath measurements and arterial indices in the diagnosis of IIH in a South Indian cohort. Further research is needed to fully understand the longitudinal relationship of these parameters and treatment outcomes in IIH.

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Optic Nerve Sheath Measurement on Ultrasound: A Novel Diagnostic Test for Giant Cell Arteritis

Baalbaki,

Dubé,

Ross

et al. 2024

ACR Open Rheumatology

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ObjectiveOptic nerve sheath enhancement on magnetic resonance imaging has been reported in patients with giant cell arteritis (GCA), with or without visual manifestations. Whether similar findings can be documented on ultrasound is unknown. Optic nerve ultrasound is a point‐of‐care, easy to learn, rapid, and noninvasive technique. This study aims to investigate whether optic nerve sheath diameter (ONSD) measured on ultrasound is useful in the diagnosis of active, new‐onset GCA.MethodsA single‐center, diagnostic accuracy study was performed from June to November 2022 on consecutive eligible patients referred for suspected GCA. Optic nerve ultrasound was performed on both eyes. The ONSD (includes the optic nerve and its sheath) and optic nerve diameter (OND) were measured 3 mm behind the ocular globe. The presence or absence of GCA was confirmed clinically 6 months later. Multivariable linear regression, adjusting for age and sex, was used to determine the association between optic nerve ultrasound measures and final GCA diagnosis.ResultsThirty participants were enrolled, including nine participants with a final diagnosis of GCA. Mean ± SD ONSD was 5.98 ± 1.17 mm in patients with GCA and 4.02 ± 0.99 mm in patients without GCA. Mean ONSD was greater by 1.26 mm in patients with GCA (95% confidence interval 0.30–2.21 mm, P = 0.01) compared with those without GCA, adjusting for age and sex. Mean ± SD OND was 2.97 ± 0.46 mm in patients with GCA and 2.47 ± 0.58 mm in patients without GCA. There was no evidence of an association between GCA diagnosis and OND.ConclusionPatients with GCA had a significantly greater ONSD on ultrasound than patients without GCA. Optic nerve ultrasound may represent a novel, rapid, bedside diagnostic test for GCA. A large prospective study is required to confirm these findings and evaluate whether ONSD can be used as a disease activity biomarker in GCA.

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B-mode transorbital ultrasonography for the diagnosis of idiopathic intracranial hypertension: an updated systematic review and meta-analysis

Cited by 3 publications

References 45 publications

Ultraschalldiagnostik peripherer Nerven und des Nervus opticus

Ultraschalldiagnostik peripherer Nerven und des Nervus opticus

Characterization of Ocular Sonography Findings and their Relationship to Clinical Features from a South Indian Cohort of Idiopathic Intracranial Hypertension

Optic Nerve Sheath Measurement on Ultrasound: A Novel Diagnostic Test for Giant Cell Arteritis

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