Babesiosis in the UK and approach to treatment

Jerram, Lucy; Willshire, Jim

doi:10.12968/live.2019.24.1.18

Cited by 3 publications

(3 citation statements)

References 25 publications

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“…However, it is of note that haemoglobinuria, reported in 80.6% of babesiosis cases, only presents late in the disease process. The fatality case rate for babesiosis in this study (35%) is markedly higher than the <10% reported following treatment by Jerram and Willshire [ 49 ] and was not linked to farm region. The sampling method we utilised potentially attracted submissions of cases with high parasitaemia that were refractory to treatment.…”

Section: Discussioncontrasting

confidence: 77%

Surveillance and Risk Analysis for Bovine Babesiosis in England and Wales to Inform Disease Distribution

McFadzean

Johnson

Phipps

et al. 2023

Animals

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Babesia divergens is a zoonotic piroplasm that infects both cattle and humans in Europe. Disease transmission occurs through Ixodes ricinus tick bites, a species that is increasing in abundance and distribution across Europe in response to climate and land-use changes. Developments in agri-environment policy and changing consumer demands may also have unintended consequences on tick-borne disease rates. Currently, B. divergens surveillance in British cattle is limited, rendering temporal trend analysis and the detection of potential zoonotic hotspots impossible. The objective of this study was to assess syndromic surveillance as a means of determining babesiosis distribution in British cattle, and to evaluate the intrinsic disease risk factors in order to respond to disease threats posed by changing environments. Samples from 95 clinically affected cattle on 70 unique holdings were screened for Babesia spp., using established blood smear examination techniques and a B. divergens-specific PCR method, between April and December 2021. B. divergens was detected in 45/95 animals (47.4%), with PCR offering the advantage of identification at species level. Infection with Anaplasma phagocytophilum was detected in 19/95 animals (20%). Co-infection was detected in five animals. The cases were recorded across multiple geographic regions and throughout the sampling period. Univariate logistic regression analysis failed to identify any statistically significant risk factors for B. divergens presence. This study demonstrates that bovine babesiosis is geographically widespread throughout England and Wales, placing a large proportion of the cattle population at risk of infection, with the potential for zoonotic transmission to humans.

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Section: Discussioncontrasting

confidence: 77%

Surveillance and Risk Analysis for Bovine Babesiosis in England and Wales to Inform Disease Distribution

McFadzean

Johnson

Phipps

et al. 2023

Animals

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show abstract

“…It is 1-1.5 m wide and 3-3.5 m long (Soulsby 1986;El Sawalhy 1999). According to (Jerram and Willshire 2019) and (Alvarez et al 2019), B. divergenis has a small, thin, and obtuse angle (Fig. 1).…”

Section: Etiology and Morphologymentioning

confidence: 99%

Babesiosis in Cattle

2023

IJAB

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“…The set of sampled animals in the present study comprised the entire herd on the farm including calves, replacement stock and older breeding animals. In the UK, clinical babesiosis is primarily observed in spring and autumn ( Jerram & Willshire, 2019 ). Although all stock had the opportunity to be exposed to ticks, as they had been previously out at pasture, the samples were collected in December, which is long after the normal spring/early summer peak in UK tick activity ( Dobson et al., 2011 ).…”

Section: Discussionmentioning

confidence: 99%