Bacteremia Following Surgical Dental Extraction with an Emphasis on                Anaerobic Strains

Rajasuo, Ari; Perkki, K; Nyfors, S.; Jousimies‐Somer, Hannele; Meurman, Jukka H.

doi:10.1177/154405910408300217

Cited by 69 publications

(62 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…According to a number of studies, the incidence of bacteremia ranges from 13 to 96%, depending on the evaluated time intervals as well as other experimental variables studied (Table 2). It has been shown that bacteremias can follow simple dental extractions as well as extractions of impacted teeth that entail minor surgical intervention (76,103,109,110,132,137,140). In such circumstances, the bacteremic incidence appears to be influenced positively by the presence of gingivitis, periodontitis, and other odontogenic infections, such as dentoalveolar abscesses, suggesting a direct relationship between an increased bacterial biofilm burden and bacteremia (15, 26, 128, 132).…”

Section: Tooth Extractionmentioning

confidence: 99%

Microbiology of Odontogenic Bacteremia: beyond Endocarditis

et al. 2009

View full text Add to dashboard Cite

SUMMARY The human gingival niche is a unique microbial habitat. In this habitat, biofilm organisms exist in harmony, attached to either enamel or cemental surfaces of the tooth as well as to the crevicular epithelium, subjacent to a rich vascular plexus underneath. Due to this extraordinary anatomical juxtaposition, plaque biofilm bacteria have a ready portal of ingress into the systemic circulation in both health and disease. Yet the frequency, magnitude, and etiology of bacteremias due to oral origin and the consequent end organ infections are not clear and have not recently been evaluated. In this comprehensive review, we address the available literature on triggering events, incidence, and diversity of odontogenic bacteremias. The nature of the infective agents and end organ infections (other than endocarditis) is also described, with an emphasis on the challenge of establishing the link between odontogenic infections and related systemic, focal infections.

show abstract

Section: Tooth Extractionmentioning

confidence: 99%

Microbiology of Odontogenic Bacteremia: beyond Endocarditis

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Bacteria commonly gain entrance to the circulation through ulcerated gingival crevicular tissue that surrounds the teeth. 23 Although dental extractions are among the most likely of dental procedures to cause bacteremia, toothbrushing may disrupt a far larger surface area of gingival crevicular tissue. Although brushing does not appear to have the same incidence and nature of bacteremia as a dental extraction, we found a substantial incidence (23%) of bacteremia of IE-causing species from this common daily oral hygiene activity.…”

Section: Discussionmentioning

confidence: 99%

“…The literature suggests that the detection of bacteria after a tooth extraction drops off sharply after 10 minutes, and isolated reports indicate that positive blood cultures can be detected for as long as 30 minutes after a dental procedure. 8,12,20,23 Finally, the extent to which systemic antibiotics reduce the incidence, duration, nature, and magnitude of bacteremia from dental procedures is controversial as well. 5,24 Clinical Perspective p 3125…”

mentioning

confidence: 99%

Bacteremia Associated With Toothbrushing and Dental Extraction

et al. 2008

View full text Add to dashboard Cite

Background-Antibiotic prophylaxis recommendations for the prevention of infective endocarditis are based in part on studies of bacteremia from dental procedures, but toothbrushing may pose a greater threat. The purpose of this study was to compare the incidence, duration, nature, and magnitude of endocarditis-related bacteremia from single-tooth extraction and toothbrushing and to determine the impact of amoxicillin prophylaxis on single-tooth extraction. Methods and Results-In this double-blind, placebo-controlled study, 290 subjects were randomized to (1) toothbrushing, (2) single-tooth extraction with amoxicillin prophylaxis, or (3) single-tooth extraction with identical placebo. Blood was drawn for bacterial culturing and identification at 6 time points before, during, and after these interventions. The focus of our analysis was on bacterial species reported to cause infective endocarditis. We identified 98 bacterial species, 32 of which are reported to cause endocarditis. Cumulative incidence of endocarditis-related bacteria from all 6 blood draws was 23%, 33%, and 60% for the toothbrushing, extraction-amoxicillin, and extraction-placebo groups, respectively (PϽ0.0001). Significant differences were identified among the 3 groups at draws 2, 3,4, and 5 (all PϽ0.05). Amoxicillin resulted in a significant decrease in positive cultures (PϽ0.0001). Conclusions-Although amoxicillin has a significant impact on bacteremia resulting from a single-tooth extraction, given the greater frequency for oral hygiene, toothbrushing may be a greater threat for individuals at risk for infective endocarditis. (Circulation. 2008;117:3118-3125.)

show abstract

Section: Bacteremia and Viridans Group Streptococcimentioning

confidence: 99%

“…Rajasuo et al (2004) found that the detectable bacteremia at 10, 15, and 30 minutes were 44%, 25%, and 13%, respectively. Most prevalent aerobes were VGS and the Streptococcus milleri group (45). The world literature on the incidence of bacteremia after dental extraction shows that the incidence of bacteremia varies from 13% to 96% Arch Pediatr Infect Dis.…”

Section: Bacteremia and Viridans Group Streptococcimentioning

confidence: 99%

Periodontitis, Bacteremia and Infective Endocarditis: A Review Study

Dhotre

Davane

Nagoba

2017

Arch Pediatr Infect Dis

View full text Add to dashboard Cite

Context: Earlier evidences show that periodontitis with inflamed and ulcerated crevicular or pocket epithelium surrounding the teeth may be a portal of entry for bacteria into the bloodstream. A newly proposed causal model predicts that an early bacteremia may affect the endothelial surface of the heart over many years and promote valve thickening rendering the heart valve susceptible to vegetation by a later bacteremia that would culminate over a few weeks into fulminant infection. Evidence Acquisition: In this review, various published sources of information pertaining to periodontitis, bacteremia and infective endocarditis were reviewed. This review is focused on the role of the viridans group streptococci (VGS) in periodontitis, bacteremia and infective endocarditis. Results: The viridans group streptococci present in the oral cavity were the most important causes of bacteremia following dental procedures and infective endocarditis. In most of the studies, significantly higher rates of bacteremia occurring in patients with periodontitis than patients without periodontitis indicated that periodontitis opens up the route for oral streptococci to gain entry into the bloodstream. In addition, the significantly higher rates of isolation of the VGS from the patients of infective endocarditis with periodontitis showed that there was a positive association between periodontitis, infective endocarditis and the VGS. Conclusions:The literature survey presented in this review suggests that there is a definite relation between periodontitis, bacteremia and infective endocarditis and would provide valuable data for the future dentists as well as the physicians, because a large proportion of the world's population lives a lifetime with periodontitis. Moreover, infective endocarditis still remains a cause of concern as this disease is a cause of considerable morbidity and mortality regardless of modern antimicrobial and surgical treatment.

show abstract

Bacteremia Following Surgical Dental Extraction with an Emphasis on Anaerobic Strains

Cited by 69 publications

References 22 publications

Microbiology of Odontogenic Bacteremia: beyond Endocarditis

Microbiology of Odontogenic Bacteremia: beyond Endocarditis

Bacteremia Associated With Toothbrushing and Dental Extraction

Periodontitis, Bacteremia and Infective Endocarditis: A Review Study

Contact Info

Product

Resources

About