Bacterial and Atypical Infections in Critically Ill Cancer Patients

Hoz, Alejandro De la; Cortés, Jorge Alberto

doi:10.1007/978-3-319-74588-6_123

Cited by 3 publications

(1 citation statement)

References 143 publications

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“…The escalation in MDR sepsis causing hospital readmissions is attributed to many factors, such as inadequate infection control, the overuse of a broad spectrum of antibiotics, not finishing the course of prescribed antibiotics, or using antibiotics when not needed, which can contribute to the emergence of MDR bacteria [37]. Immunocompromised patients, such as those with chronic illnesses or receiving treatments such as chemotherapy, are more susceptible to MDR infections [39]. Delayed diagnosis or the inappropriate treatment of severe sepsis can lead to the persistence and spread of MDR bacteria [40].…”

Section: Factors Contributing To the Rise Of Mdr In Sepsis In Geriatr...mentioning

confidence: 99%

Inflammaging in Multidrug-Resistant Sepsis of Geriatric ICU Patients and Healthcare Challenges

Kumar,

Balraj,

Shivashankar

et al. 2024

Geriatrics

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Multidrug-resistant sepsis (MDR) is a pressing concern in intensive care unit (ICU) settings, specifically among geriatric patients who experience age-related immune system changes and comorbidities. The aim of this review is to explore the clinical impact of MDR sepsis in geriatric ICU patients and shed light on healthcare challenges associated with its management. We conducted a comprehensive literature search using the National Center for Biotechnology Information (NCBI) and Google Scholar search engines. Our search incorporated keywords such as “multidrug-resistant sepsis” OR “MDR sepsis”, “geriatric ICU patients” OR “elderly ICU patients”, and “complications”, “healthcare burdens”, “diagnostic challenges”, and “healthcare challenges” associated with MDR sepsis in “ICU patients” and “geriatric/elderly ICU patients”. This review explores the specific risk factors contributing to MDR sepsis, the complexities of diagnostic challenges, and the healthcare burden faced by elderly ICU patients. Notably, the elderly population bears a higher burden of MDR sepsis (57.5%), influenced by various factors, including comorbidities, immunosuppression, age-related immune changes, and resource-limited ICU settings. Furthermore, sepsis imposes a significant economic burden on healthcare systems, with annual costs exceeding $27 billion in the USA. These findings underscore the urgency of addressing MDR sepsis in geriatric ICU patients and the need for tailored interventions to improve outcomes and reduce healthcare costs.

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Section: Factors Contributing To the Rise Of Mdr In Sepsis In Geriatr...mentioning

confidence: 99%