Bacterial community-acquired pneumonia: risk factors for mortality and supportive therapies

Lode, H.

doi:10.1007/s00134-008-1366-3

Cited by 4 publications

(2 citation statements)

References 17 publications

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“…Limited Australian data indicate that 10% to 35% of patients hospitalised with CAP require admission to an ICU because of respiratory failure and septic shock resulting from severe infection, and mechanical ventilation is necessary in 73% of these cases . The mortality rate of patients admitted to ICU for CAP is 20% to 50% despite advances in medical science over the last 4 decades and adequate initiation of antibiotic treatment …”

Section: Introductionmentioning

confidence: 99%

A survey of clinicians regarding respiratory physiotherapy intervention for intubated and mechanically ventilated patients with community‐acquired pneumonia. What is current practice in Australian ICUs?

Lee

Hill

Patman

2017

Evaluation Clinical Practice

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Section: Introductionmentioning

confidence: 99%

A survey of clinicians regarding respiratory physiotherapy intervention for intubated and mechanically ventilated patients with community‐acquired pneumonia. What is current practice in Australian ICUs?

Lee

Hill

Patman

2017

Evaluation Clinical Practice

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“…Although antibiotic therapy is of utmost importance, particularly in severe CAP, adequate antibiotic therapy alone, even when optimally used, is probably not sufficient to reduce mortality [Lode, 2009]. Therefore, interest in nonantibiotic, adjunctive therapy has continued to grow [Cohen, 2009].…”

Section: Treatment Failure In Community-acquired Pneumoniamentioning

confidence: 99%

Community-acquired pneumonia: identification and evaluation of nonresponders

Gonçalves-Pereira

Conceição

Póvoa

2013

Therapeutic Advances in Infection

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Community acquired pneumonia (CAP) is a relevant public health problem, constituting an important cause of morbidity and mortality. It accounts for a significant number of adult hospital admissions and a large number of those patients ultimately die, especially the population who needed mechanical ventilation or vasopressor support.Thus, early identification of CAP patients and its rapid and appropriate treatment are important features with impact on hospital resource consumption and overall mortality. Although CAP diagnosis may sometimes be straightforward, the diagnostic criteria commonly used are highly sensitive but largely unspecific. Biomarkers and microbiological documentation may be useful but have important limitations.Evaluation of clinical response is also critical especially to identify patients who fail to respond to initial treatment since these patients have a high risk of in-hospital death. However, the criteria of definition of non-response in CAP are largely empirical and frequently markedly diverse between different studies. In this review, we aim to identify criteria defining nonresponse in CAP and the pitfalls associated with this diagnosis. We also aim to overview the main causes of treatment failure especially in severe CAP and the possible strategies to identify and reassess non-responders trying to change the dismal prognosis associated with this condition.

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Impfungen in der Pneumologie

Forstner

Pletz

2014

Pneumologie

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Zusammenfassung Die effektivste Ma?nahme zur Pr?vention von Infektionen des Respirationstrakts ist der Einsatz von Schutzimpfungen gegen wichtige respiratorische Pathogene. Aufgrund ihrer gro?en klinischen Relevanz wird die Vakzinierung gegen?ber Pneumokokken, Influenza A/B-Virus und Bordetella pertussis nicht nur im Kindesalter, sondern auch im Erwachsenenalter von der St?ndigen Impfkommission am Robert Koch Institut empfohlen. In der vorliegenden ?bersichtsarbeit werden die klinische Bedeutung und Sicherheit der entsprechenden Impfungen anhand der aktuellen Datenlage als auch die Vor- und Nachteile der unterschiedlichen verf?gbaren Impfstoffe diskutiert.

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Bacterial community-acquired pneumonia: risk factors for mortality and supportive therapies

Cited by 4 publications

References 17 publications

A survey of clinicians regarding respiratory physiotherapy intervention for intubated and mechanically ventilated patients with community‐acquired pneumonia. What is current practice in Australian ICUs?

A survey of clinicians regarding respiratory physiotherapy intervention for intubated and mechanically ventilated patients with community‐acquired pneumonia. What is current practice in Australian ICUs?

Community-acquired pneumonia: identification and evaluation of nonresponders

Impfungen in der Pneumologie

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