Bacterial Detection by Using Micro Immunosensing Biomedical Cavity Resonator

Elsheakh, Dalia M.; Ismail, Mohd Hafiz; Elsadek, Hala; Abdallah, Esmat A.; Moghannem, Saad A.; Elmazny, Waleed N.

doi:10.1049/cp.2018.1023

Cited by 3 publications

(6 citation statements)

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“…small [18] Biosensors are an attractive method for label-free capability of monitoring bacteria and viruses [19]. A microwave resonator is extensively used nowadays as a contactless and non-invasive method for virus detection with a transmission coefficient |S 21 | [20] resonant frequency and quality factor [21,22].…”

Section: Moderate Price and Fast Resultsmentioning

confidence: 99%

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Rapid Detection of Coronavirus (COVID-19) Using Microwave Immunosensor Cavity Resonator

Elsheakh

Ahmed

Elashry

et al. 2021

Sensors

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This paper presents a rapid diagnostic device for the detection of the pandemic coronavirus (COVID-19) using a micro-immunosensor cavity resonator. Coronavirus has been declared an international public health crisis, so it is important to design quick diagnostic methods for the detection of infected cases, especially in rural areas, to limit the spread of the virus. Herein, a proof-of-concept is presented for a portable laboratory device for the detection of the SARS-CoV-2 virus using electromagnetic biosensors. This device is a microwave cavity resonator (MCR) composed of a sensor operating at industrial, scientific and medical (ISM) 2.45 GHz inserted in 3D housing. The changes of electrical properties of measured serum samples after passing the sensor surface are presented. The three change parameters of the sensor are resonating frequency value, amplitude and phase of the reflection coefficient |S11|. This immune-sensor offers a portable, rapid and accurate diagnostic method for the SARS-CoV-2 virus, which can enable on-site diagnosis of infection. Medical validation for the device is performed through biostatistical analysis using the ROC (Receiver Operating Characteristic) method. The predictive accuracy of the device is 63.3% and 60.6% for reflection and phase, respectively. The device has advantages of low cost, low size and weight and rapid response. It does need a trained technician to operate it since a software program operates automatically. The device can be used at ports’ quarantine units, hospitals, etc.

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Section: Moderate Price and Fast Resultsmentioning

confidence: 99%

“…The main idea behind this device was published early in [18]. The system consists, as shown in Figure 1, of the following main components: microfluidic pump, pocket vector network analyzer, 3D dimension housing, waste containers with silicon tubes, and control software.…”

Section: Moderate Price and Fast Resultsmentioning

confidence: 99%

Rapid Detection of Coronavirus (COVID-19) Using Microwave Immunosensor Cavity Resonator

Elsheakh

Ahmed

Elashry

et al. 2021

Sensors

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“…Electromagnetics‐based sensing is also expanding in medicine, bacteria and virus detection, and imaging, because of their customizable characteristics. In the last few years, several studies have used sensing antennas in the radio frequencies ranges . The sensitivity of the designed sensor depends on the chosen operating frequency, the sample dielectric properties and size, and the form of the sample material (liquid, solid, gas, powder, etc).…”

Section: Introductionmentioning

confidence: 99%

“…The sensitivity of the designed sensor depends on the chosen operating frequency, the sample dielectric properties and size, and the form of the sample material (liquid, solid, gas, powder, etc). Correas‐Serrano et al and Elsheakh et al introduced a cavity resonator antenna to sense the bacteria at a frequency range of 2.4 GHz, based on the proximity coupled feed method. The antenna was designed on Rogers substrate with thickness 1.28 mm and size 50 mm×50 mm.…”

Section: Introductionmentioning

confidence: 99%

“…In the last few years, several studies have used sensing antennas in the radio frequencies ranges. [24][25][26][27][28] The sensitivity of the designed sensor depends on the chosen operating frequency, the sample dielectric properties and size, and the form of the sample material (liquid, solid, gas, powder, etc). Correas-Serrano et al 26 and Elsheakh et al 27 introduced a cavity resonator antenna to sense the bacteria at a frequency range of 2.4 GHz, based on the proximity coupled feed method.…”

Section: Introductionmentioning

confidence: 99%

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Using millimeter‐waves for rapid detection of pathogenic bacteria in food based on bacteriophage

Sultan

Ali

Fahmy

et al. 2019

Engineering Reports

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The accessibility of a rapid method for detection and identification of food‐borne pathogens is crucial for food industry worldwide. Antibiotic resistance bacteria (eg, E. coli) that can enter the food chain in different ways, can indeed survive on foods causing disease to humans. Hence, the introduction of a rapid detection technology becomes necessary for the food industry to ensure consumer safety, especially for products with short shelf lives. Bacteriophages can be used to detect and identify bacteria. In this study, a novel biosensor is proposed to detect pathogens by means of phage‐based baroreceptor. The biosensing technique is based on millimeter‐waves technology in the 30 to 60 GHz frequency range. The proposed biosensor can detect the pathogenic bacteria in different food samples by using a diamond‐shape microstrip slot antenna. The bacteriophage‐bacterium interaction is detected through the dynamic changes in transmission lines and antennas responses. The correctness of the antenna to detect E. coli in real food sample (tomato) is also investigated. The results indicate that, through the designed sensing elements, the transient interaction between bacteria and phage can effectively be detected. This sensing mechanism allows for a faster, more accurate, and low‐cost detection of pathogenic bacteria than traditional assays. Finally, the results are compared with previously reported sensing techniques.

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Role of presence of gold nanoparticles on enhancement of RF biosensing sensitivity

et al. 2023

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In this work, we explore the enhancement of sensitivity of sensing of biomolecules using Radio Frequency (RF) based sensing, by utilizing gold particles. In particular, we investigate the impact of various parameters of gold particles such as shape, size and arrangements on enhancing sensitivity. The work uses a Microstrip Patch Antenna designed to resonate at 96.84 GHz. The sensor is facile, rapid and efficient, and uses sample volume of 17.5 nL. The results indicate that the presence of gold particles helps in improving the performance of RF sensors in detecting biomolecules. However, the extent of improvement depends on the properties of gold particles and is in the range of 30-80% for the different cases studied in this work.

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Bacterial Detection by Using Micro Immunosensing Biomedical Cavity Resonator

Cited by 3 publications

References 0 publications

Rapid Detection of Coronavirus (COVID-19) Using Microwave Immunosensor Cavity Resonator

Rapid Detection of Coronavirus (COVID-19) Using Microwave Immunosensor Cavity Resonator

Using millimeter‐waves for rapid detection of pathogenic bacteria in food based on bacteriophage

Role of presence of gold nanoparticles on enhancement of RF biosensing sensitivity

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