Bacterial Endocarditis in Pregnancy

Ward, Humphry; Hickman, Rachel

doi:10.1111/j.1479-828x.1971.tb00477.x

Cited by 40 publications

(22 citation statements)

References 8 publications

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“…Studies have reported rates of GBS colonization in pregnant women of 4.6% to 40.6% [1, 4, 5]. Fifty percent of colonized mothers transmit GBS to their newborns [1].…”

Section: Discussionmentioning

confidence: 99%

Tricuspid Valve Endocarditis With Group B Streptococcus After an Elective Abortion: The Need for New Data

Palys

Li²,

Gaut³

et al. 2006

Infectious Diseases in Obstetrics and Gynecology

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Streptococcus agalactiae, commonly known as Group B streptococcus (GBS), was originally discovered as a cause of bovine mastitis. GBS colonizes the genital tract of up to 40% of women and has become a major pathogen in neonatal meningitis. GBS endocarditis is thought to be an uncommon manifestation of this infection and carries a higher mortality compared to other streptococcal pathogens. Studies have shown that endocarditis after abortion has an incidence of about one per million. However, this figure was published prior to routine use of echocardiography for diagnosis. The American Heart Association has recently declared transesophageal echocardiography the gold standard for endocarditis diagnosis. This case report illustrates that, given the potentially devastating consequences of endocarditis, there is a need for updated studies to adequately assess the true incidence of this infection. Pending the outcome of these studies, routine GBS screening and prophylactic antibiotics prior to abortion should be recommended.

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“…Studies have reported rates of GBS colonization in pregnant women of 4.6% to 40.6% [1, 4, 5]. Fifty percent of colonized mothers transmit GBS to their newborns [1].…”

Section: Discussionmentioning

confidence: 99%

Tricuspid Valve Endocarditis With Group B Streptococcus After an Elective Abortion: The Need for New Data

Palys

Li²,

Gaut³

et al. 2006

Infectious Diseases in Obstetrics and Gynecology

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“…Infective endocarditis (IE) in pregnancy is a rare and life-threatening condition with a reported incidence of 0.006% and a maternal mortality rate of 15–20% 1 2. Reports suggest that IVDU is becoming a more common risk factor for infective endocarditis in pregnancy,3 and now accounts for up to 14% of cases.…”

Section: Discussionmentioning

confidence: 99%

Multivalvular infective endocarditis in pregnancy presenting with septic pulmonary emboli

English

Weston²

2015

BMJ Case Reports

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SUMMARYA 33-year-old woman presented at 36 weeks gestation with worsening respiratory distress. A CT-pulmonary angiogram was performed to rule out a massive pulmonary embolism; instead, this identified extensive septic pulmonary emboli throughout both lung fields. Given the continuing maternal deterioration, a non-elective caesarean section was performed. A transoesophageal echocardiogram identified multiple large cardiac valve vegetations on both sides of her heart with an associated aortic root abscess. She responded well to a 6-week course of intravenous antibiotics. BACKGROUND

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“…Jinekolojik ve doğum işlemleri sonrasında infektif endokardit gelişme riski düşüktür 0.03-0.14/1000 doğum (4,5). Dahası elektif abortusda infektif endokardit sıklığının çok daha düşük olacağı tahmin edilmektedir 0.001/1000 doğum (4).…”

Section: Discussionunclassified

Staphylococcus Hominis Native Tricuspid Valve Endocarditis Following Spontaneous Abortus

Soydinç

Yüce²,

Sarı³

et al. 2012

JAEM

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OlguDaha önceden bilinen kardiyak hastalık veya şikayet öyküsü olmayan 31 yaşında kadın hastada ikinci gebeliğinin 5. haftasında (gravida 2, para 1) vaginal kanama şikayeti ile acil polikliniğe başvuran hastada komplet abortus saptanılıp takip ve tedavi ediliyor. Abortustan 3 gün sonra ateş, titreme, halsizlik yakınmaları başlayan hastaya dış merkezde nonspesifik antibiyotik tedavileri başlanmış şikayetleri düzelmeyen hasta abortustan 1 ay sonra hastanemize sevkedilmiş.Kliniğimize gelişte hastanın yüksek ateş, halsizlik ve yorgunluk şikayeti vardı. Bilinen bir hastalığı yoktu ve düzenli ilaç kullanım öyküsü, madde bağımlılığı bulunmuyordu. Fizik muayenede ateş 39 derece, nabız 128/dk, kan basıncı 90/60mmHg, arteriyel oksijen satürasyonu %95 idi. Akciğer sesleri doğal olmakla birlikte bazallerde solunum sesleri azalmıştı. Kalp sesleri doğal ek ses yoktu fakat sternumun sol tarfında holosistolik 2/6 şiddetinde üfürüm duyuldu. Batın ve pelvik muayenede özellik yoktu. Cilt muayenesi normaldi. Ödem ve siyanoz tespit edilmedi. Hastanın laboratuar bulgularında sedimantasyon 60mm/ saat, CRP 110 mg/dl, lökosit 30.000/mm 3 ve nötrofil değerleri yüksek (%88) olarak tespit edildi. Tam idrar tahlilinde özelik yoktu. Diğer biyokimya değerlerinde özellik yoktu. Hastaya infektif endokardit şüphesi ile transtorasik ekokardiyografi (TTE) yapıldı ve tiküspit kapak üzerinde 0.8x1.2 cm boyutunda vejetasyon, orta derece triküspit yetersizliği izlendi (Resim 1). Hastadan 3 adet kan kültürü alındı ve infektif endokarditi tanısı ile hastaya vankomisin 500 mg 4x1 ve imipenem 500 mg AbstractThe patient had a spontaneous abortion in the fifth week of her pregnancy and had nonspecific treatment due to fever and chills that had started 3 days after the spontaneous abortion. She was diagnosed and treated as endocarditis as there was vegetation on the tricuspid valve on transthoracic echocardiography, and blood culture revealed Stphylococcus Hominis. The patient completely recovered from endocarditis after antibiotic treatment and had another pregnancy ending with normal birth without any complication. Stphylococcus Hominis is a coagulase negative microorganism that normaly exists in skin flora, causing endocarditis more commonly in immunesuppressed subjects, patients with prosthetic valves and acessory devices. Here in this case report, we present a 31 year-old woman who had the complication of native tricuspid valve endocarditis after spontaneous abortus in her fifth week of pregnancy. To our knowledge, the present case is the first to be reported as a native valve endocarditis caused by Stphylococcus Hominis associated with pregnancy or abortus. (JAEM 2012; 11: 47-9) Özet Gebeliğinin 5. haftasında spontan abortus meydana gelen ve abortustan 3 gün sonra yüksek ateş, titreme ve üşüme şikayetleri başlayan hastaya nonspesifik tedaviler başlanmış. Sonrasında yapılan transtorasik ekokardiyogrjafide triküspit kapakta vejetasyon ve kan kültüründe Stafilokokus Hominis üremesi olması üzerine infektif endokardit tedavisi başlandı. Antibiyotik tedavi ...

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Bacterial Endocarditis in Pregnancy

Abstract: Five cases of bacterial endocarditis associated with pregnancy are described. Despite modem therapy, the seriousness of the condition prevails. Emergency vaIve replacement during the acute stage of the disease is now possible.

Cited by 40 publications

References 8 publications

Tricuspid Valve Endocarditis With Group B Streptococcus After an Elective Abortion: The Need for New Data

Tricuspid Valve Endocarditis With Group B Streptococcus After an Elective Abortion: The Need for New Data

Multivalvular infective endocarditis in pregnancy presenting with septic pulmonary emboli

Staphylococcus Hominis Native Tricuspid Valve Endocarditis Following Spontaneous Abortus

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