Bacterial endocarditis in the pig with special reference to streptococcal endocarditis

Jones, J.E.T.

doi:10.1016/0021-9975(80)90024-9

Cited by 20 publications

(26 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Generally, all vegetations were present with a core of granulation tissue overlaid by fibrin similar to previous descriptions. 8,11,22 The histomorphology of the inflammatory reaction in endocardial vegetations caused by streptococci was characterized by a low-tomoderate infiltration with neutrophils. The cells were usually situated in small foci, embedded in the granulation tissue, and surrounded by fibroblasts and macrophages.…”

Section: Histopathologymentioning

confidence: 99%

“…In the majority of studies focusing on spontaneous porcine endocarditis, the evaluation of lesions has been based solely on gross inspection usually combined with microbiological examinations. 16,18,20 If histopathology has been applied, only a few cases were examined or the age group in focus has been dominated by recently weaned piglets and/or sows, 8,11 or the lesions were selected to contain only a single bacterium, such as Streptococcus suis. 22,25 From such studies, it is well established that S. suis and Erysipelothrix rhusiopathiae are the dominant agents of porcine endocarditis.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Histologic and Bacteriologic Findings in Valvular Endocarditis of Slaughter-Age Pigs

et al. 2010

View full text Add to dashboard Cite

Abstract. Endocarditis lesions from 117 slaughter pigs were examined pathologically and etiologically in addition to 90 control hearts with cardiac valves. Lesions were located on the valves; however, the lesions had extended to the walls in 21 cases (18%). Lesions predominated on the mitral valve (59%). A total of 28 cases, from which no growth was obtained or a contamination flora was grown, were screened by fluorescence in situ hybridization (FISH) for bacteria (general bacterial probe) and probes specific for Streptococcus suis and Erysipelothrix rhusiopathiae, respectively. Using FISH, an additional 10 cases of endocarditis due to S. suis and E. rhusiopathiae were disclosed. Within lesions, streptococci predominated (53%) followed by E. rhusiopathiae (30%). Distinct features of both the lesions and the shape and localization of bacterial colonies were related to streptococci and E. rhusiopathiae. The propensity for streptococci to be localized on more than 1 valve in single hearts may be because S. suis-infected pigs tend to have been infected for a longer period compared with E. rhusiopathiae. Mineralization of endocarditis lesions was significantly associated with infection by streptococci, and was seen in 71% of the cases, whereas it was present in only 28% of lesions caused by E. rhusiopathiae. In addition, areas with mineralization were significantly correlated to the presence of a granulomatous reaction. Granulomatous endocarditis is likely a result of a foreign body reaction due to dystrophic mineralization. Local proliferation of valvular endothelial cells, found in 9 hearts in the current study, may increase the risk of developing thrombosing endocarditis in pigs.

show abstract

Section: Histopathologymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Histologic and Bacteriologic Findings in Valvular Endocarditis of Slaughter-Age Pigs

et al. 2010

View full text Add to dashboard Cite

show abstract

“…(324) It is of interest that streptococci belonging to groups C and L are the most common causes of spontaneous IE in the pig. (336) Group B streptococci, originally believed to have their principal importance as pathogens in obstetrics and perinatal practice, have been emerging as an important cause of IE in adults. The rate at which cases are being reported in the literature suggests either that the bacterium is only now emerging as an important pathogen or that it is being separated from other ~-hemolytic streptococci more often due to utilization of more sophisticated techniques in routine laboratory studies.…”

Section: Il-hemolytic Streptococcimentioning

confidence: 99%

Infective Endocarditis and Other Intravascular Infections

Freedman¹

1982

View full text Add to dashboard Cite

show abstract

“…Streptococcal species are an important cause of various infections in many animal species. In veterinary diagnostic laboratories, there are eight streptococcal species frequently isolated from animal sources: Streptococcus agalactiae and S. uberis, known as the causative agent of bovine mastitis; S. dysgalactiae, which is associated with bovine mastitis and various infections in other animals; S. equi, which causes ''strangles'' and other infections in horses; S. porcinus and S. suis, which are associated with various infections in pigs; S. canis, isolated from bovine mastitis and various infections in dogs; and S. bovis known to exist in the alimentary tract of cattle and to be the causative agent of various animal infections [2,5,7,11,15,17,18,26]. The identification of these bacteria currently relies on Lancefield serogrouping and analysis of biochemical activity.…”

Section: Introductionmentioning

confidence: 99%

Simple and rapid PCR method for identification of streptococcal species relevant to animal infections based on 23S rDNA sequence

KAWATA

2004

FEMS Microbiology Letters

View full text Add to dashboard Cite

A PCR identification system targeting 23S rDNA sequences for the identification of eight streptococcal species relevant to animal infections (Streptococcus agalactiae, S. bovis, S. canis, S. dysgalactiae, S. equi, S. porcinus, S. suis and S. uberis) was developed. This system consists of two PCR reactions, A and B, in which seven and eight primers, respectively, are used simultaneously, and was designed so that each amplification product indicates a species by its size. A total of 111 cultures, including the type strain of eight species, could be successfully identified and differentiated as individual species, except for the cross reactivity between S. bovis and S. equinus. The developed PCR system can complete the identification procedure for eight streptococcal species through two tube reactions per isolate, and, therefore, might provide a rapid, simple and accurate diagnostic tool for veterinary laboratories.

show abstract

Bacterial endocarditis in the pig with special reference to streptococcal endocarditis

Cited by 20 publications

References 11 publications

Histologic and Bacteriologic Findings in Valvular Endocarditis of Slaughter-Age Pigs

Histologic and Bacteriologic Findings in Valvular Endocarditis of Slaughter-Age Pigs

Infective Endocarditis and Other Intravascular Infections

Simple and rapid PCR method for identification of streptococcal species relevant to animal infections based on 23S rDNA sequence

Contact Info

Product

Resources

About