Bacterial extracellular vesicles in biofluids as potential diagnostic biomarkers

Su, Kar-Yan; Kok, Jie-Yi Koh; Chua, Yie-Wei; Ong, Shearn-Dior; Ser, Hooi‐Leng; Pusparajah, Priyia; Saw, Pui San; Goh, Bey Hing; Lee, Wai Leng

doi:10.1080/14737159.2022.2166403

Cited by 6 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The exchange of BEVs between pathogens during host damage not only serves as improved biomarkers for pathogenic processes, but also offers potential for monitoring local and systemic infections, making them valuable for diagnosing infectious diseases ( 131 ). BEVs are an emerging biomarker that can be detected through liquid biopsy, opening up new diagnostic possibilities for various diseases ( 132 ). Furthermore, clinical analysis of BEVs isolated from biological fluids of patients and healthy controls has identified two distinct groups.…”

Section: Repurposing Bevs In Medical Applicationsmentioning

confidence: 99%

Interaction between intestinal flora and gastric cancer in tumor microenvironment

Yang

2024

Front. Oncol.

View full text Add to dashboard Cite

Gastric Cancer (GC) is a prevalent malignancy globally and is the third leading cause of cancer-related deaths. Recent researches focused on the correlation between intestinal flora and GC. Studies indicate that bacteria can influence the development of gastrointestinal tumors by releasing bacterial extracellular vesicles (BEVs). The Tumor microenvironment (TME) plays an important role in tumor survival, with the interaction between intestinal flora, BEVs, and TME directly impacting tumor progression. Moreover, recent studies have demonstrated that intestinal microflora and BEVs can modify TME to enhance the effectiveness of antitumor drugs. This review article provides an overview and comparison of the biological targets through which the intestinal microbiome regulates TME, laying the groundwork for potential applications in tumor diagnosis, treatment, and prognosis.

show abstract

Section: Repurposing Bevs In Medical Applicationsmentioning

confidence: 99%

Interaction between intestinal flora and gastric cancer in tumor microenvironment

Yang

2024

Front. Oncol.

View full text Add to dashboard Cite

show abstract

“…Yet, it is evident that the search for microbial-derived disease biomarkers for endometriosis is still in the infancy stage, especially for its implementation in clinical applications. Further studies would need to be conducted to resolve the heterogeneity issue observed in different clinical studies, given that these differences in data may arise from several factors including ethnicity, diet, or specimen quality [ 150 , 151 , 152 ]. Functional analysis of the microbiome using whole genome shotgun metagenomic sequencing can possibly provide more insights into the functional characteristics of specific microbes in the specimens.…”

Section: Future Recommendations and Conclusionmentioning

confidence: 99%

Current Updates on the Role of Microbiome in Endometriosis: A Narrative Review

et al. 2023

Self Cite

View full text Add to dashboard Cite

Endometriosis affects approximately 6 to 10% of reproductive-age women globally. Despite much effort invested, the pathogenesis that promotes the development, as well as the progression of this chronic inflammatory disease, is poorly understood. The imbalance in the microbiome or dysbiosis has been implicated in a variety of human diseases, especially the gut microbiome. In the case of endometriosis, emerging evidence suggests that there may be urogenital-gastrointestinal crosstalk that leads to the development of endometriosis. Researchers may now exploit important information from microbiome studies to design endometriosis treatment strategies and disease biomarkers with the use of advanced molecular technologies and increased computational capacity. Future studies into the functional profile of the microbiome would greatly assist in the development of microbiome-based therapies to alleviate endometriosis symptoms and improve the quality of life of women suffering from endometriosis.

show abstract

Exploring bacterial extracellular vesicles: Focus on WHO critical priority pathogens

Rocha Minarini

2024

Current Topics in Membranes

View full text Add to dashboard Cite

Bacterial extracellular vesicles in biofluids as potential diagnostic biomarkers

Cited by 6 publications

References 27 publications

Interaction between intestinal flora and gastric cancer in tumor microenvironment

Interaction between intestinal flora and gastric cancer in tumor microenvironment

Current Updates on the Role of Microbiome in Endometriosis: A Narrative Review

Exploring bacterial extracellular vesicles: Focus on WHO critical priority pathogens

Contact Info

Product

Resources

About