Bacterial inactivation characteristics of magnesium–calcium–zinc alloys for bone implants

Son, Jaehyoung; Oh, Jun Kyun; Cho, Dae Hyun; Akbulut, Mustafa; Teizer, W.

doi:10.1557/mrc.2020.80

Cited by 3 publications

(2 citation statements)

References 14 publications

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“…An analysis of the literature shows that there is still no consensus on the nature of the anti-bacterial activity of magnesium alloys. The main mechanisms of toxic action discussed in the literature are [2][3][4][5]: (1) the high reactivity of Mg in contact with aqueous media, leading to the formation of superoxide ions (O 2− ); (2) an excess of magnesium ions in the aqueous medium surrounding the cells, leading to osmotic effects that destroy cell's membranes; (3) an increase in pH during the corrosion of magnesium in biological media. Additionally, two mechanisms specific to any superhydrophobic material should be taken into account [28][29][30][31][32]: (4) the low adhesion of bacterial cells to the superhydrophobic surface; and (5) the mechanical damage of cell membranes in the cells deposited onto the surface.…”

Section: Antibacterial Activity Of Superhydrophobic Coatings In Bacterial Dispersionsmentioning

confidence: 99%

“…The rapid and weakly controllable degradation rate of magnesium and its alloys greatly hampers the clinical use of these materials. Therefore, significant efforts are currently 2 of 16 being made in analyzing the mechanism of antibacterial activity of magnesium-based alloys [2][3][4][5], and finding the ways to slow down the rate of degradation. Among the most promising options for protection against degradation are magnesium alloying [6][7][8], the use of particles of magnesium or magnesium alloys as fillers for polymer matrices [9][10][11], deposition of protective layers on magnesium alloy substrates [12], and the use of treatments of magnesium alloys, leading to a superhydrophobic state in the surface [13][14][15][16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial Activity and Degradation of Superhydrophobic Magnesium Substrates in Bacterial Media

Emelyanenko

Kaminsky

Пыцкий

et al. 2021

Metals

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The interest in magnesium-based materials is promoted by their biocompatibility, their bioresorbability, and their recently discovered antibacterial potential. Until now, the widespread use of magnesium alloys in different corrosive environments was inhibited by their weakly controllable degradation rate and poorly understood microbiologically induced corrosion behavior. To better understand the degradation and usability of magnesium-based alloys, in this study we have fabricated superhydrophobic coatings on a magnesium-based alloy, and analyzed the behavior of this alloy in bacterial dispersions of Pseudomonas aeruginosa and Klebsiella pneumoniae cells in phosphate-buffered saline. It was shown that the immersion of such coatings in bacterial dispersions causes notable changes in the morphology of the samples, dependent on the bacterial dispersion composition and the type of bacterial strain. The interaction of the superhydrophobic coatings with the bacterial dispersion caused the formation of biofilms and sodium polyphosphate films, which provided enhanced barrier properties in magnesium dissolution and hence in dispersion medium alkalization, eventually leading to the inhibition of magnesium substrate degradation. The electrochemical data obtained for superhydrophobic samples in continuous contact with corrosive bacterial dispersions for 48 h indicated a high level of anticorrosion protection.

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Section: Antibacterial Activity Of Superhydrophobic Coatings In Bacterial Dispersionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity and Degradation of Superhydrophobic Magnesium Substrates in Bacterial Media

Emelyanenko

Kaminsky

Пыцкий

et al. 2021

Metals

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Dual-functional superhydrophobic coatings on biodegradable Mg alloys via nano-SiO2 particles assisted surface modification

Son,

Cho,

Kim

et al. 2024

Surface and Coatings Technology

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Metallization of leaf-derived lignocellulose scaffolds for high-performance flexible electronics and oligodynamic disinfection

Nair,

Nita-Lazar,

Badescu

et al. 2024

npj Flex Electron

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Vascular tubules in natural leaves form quasi-fractal networks that can be metallized. Traditional metallization techniques for these lignocellulose structures are complex, involving metal sputtering, nanoparticle solutions, or multiple chemical pretreatments. Here we present a novel, facile, and reliable method for metallizing leaf-derived lignocellulose scaffolds using silver microparticles. The method achieves properties on-par with the state-of-the-art, such as broadband optical transmittance of over 80%, sheet resistances below 1 Ω/sq., and a current-carrying capacity exceeding 6 A over a 2.5 × 2.5 cm² quasi-fractal electrode. We also demonstrate copper electrodeposition as a cost-effective approach towards fabricating such conductive, biomimetic quasi-fractals. Additionally, we show that these metallized structures can effectively eliminate pathogenic microorganisms like fecal coliforms and E. coli, which are bacterial indicators of microbiological contamination of water. We finally show that these oligodynamic properties can be significantly enhanced with a small externally applied voltage, indicating the noteworthy potential of such structures for water purification and pollution control.

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Bacterial inactivation characteristics of magnesium–calcium–zinc alloys for bone implants

Cited by 3 publications

References 14 publications

Antimicrobial Activity and Degradation of Superhydrophobic Magnesium Substrates in Bacterial Media

Antimicrobial Activity and Degradation of Superhydrophobic Magnesium Substrates in Bacterial Media

Dual-functional superhydrophobic coatings on biodegradable Mg alloys via nano-SiO2 particles assisted surface modification

Metallization of leaf-derived lignocellulose scaffolds for high-performance flexible electronics and oligodynamic disinfection

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