2024
DOI: 10.1038/s44320-024-00067-0
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Bacterial live therapeutics for human diseases

Elisabet Frutos-Grilo,
Yamile Ana,
Javier Gonzalez-de Miguel
et al.

Abstract: The genomic revolution has fueled rapid progress in synthetic and systems biology, opening up new possibilities for using live biotherapeutic products (LBP) to treat, attenuate or prevent human diseases. Among LBP, bacteria-based therapies are particularly promising due to their ability to colonize diverse human tissues, modulate the immune system and secrete or deliver complex biological products. These bacterial LBP include engineered pathogenic species designed to target specific diseases, and microbiota sp… Show more

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