Bacterial memory in antibiotic resistance evolution and nanotechnology in evolutionary biology

Zhang, Chengdong; Yan, Kang; Qian, Xiang; Ma, Yayun; Guo, Quanyi

doi:10.1016/j.isci.2023.107433

Cited by 5 publications

(4 citation statements)

References 99 publications

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“…These disturbances are caused by alterations in the structure, permeability, and transport activity of the membrane. [ 19,21–23 ] 3D Nanoflowers are a recently developed type of nanomaterials that show great potential in the rapid and accurate detection of diseases like Parkinson's disease and Alzheimer's disease. These nanoflowers have been discovered to have site‐specific effects and can be used for controlled drug delivery.…”

Section: Resultsmentioning

confidence: 99%

“…Additionally, nanorods and nanosheets contribute to cell death mediated by oxidative stress, involving both ROS-dependent and ROS-independent mechanisms. [13][14][15][16][17][18][19][20][21][22][23] The cytotoxicity of ZnO-NMts has been demonstrated in both in vitro and in vivo studies using various mammalian cells. Different levels of toxicity have been observed on human A549 cells, human gingiva cells, zebrafish cells, HepG2 cells, and human endothelial cells.…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, nanorods and nanosheets contribute to cell death mediated by oxidative stress, involving both ROS‐dependent and ROS‐independent mechanisms. [ 13–23 ]…”

Section: Introductionmentioning

confidence: 99%

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Screening of low‐toxic zinc oxide nanomaterials and study the apoptosis mechanism of NSC‐34 cells

Li,

Lu,

et al. 2024

Biotechnology Journal

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With the increasing application of ZnO nanomaterials (ZnO‐NMts) in the biomedical field, it is crucial to assess their potential risks to humans and the environment. Therefore, this study aimed to screen for ZnO‐NMts with low toxicity and establish safe exposure limits, and investigate their mechanisms of action. The study synthesized 0D ZnO nanoparticles (ZnO NPs) and 3D ZnO nanoflowers (ZnO Nfs) with different morphologies using a hydrothermal approach for comparative research. The ZnO‐NMts were characterized using X‐ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Mouse brain neuronal cells (NSC‐34) were incubated with ZnO NMts for 6, 12, and 24 h, and the cell morphology was observed using TEM. The toxic effects of ZnO Nfs on NSC‐34 cells were studied using CCK‐8 cell viability detection, reactive oxygen species (ROS) measurement, caspase‐3 activity detection, Annexin V‐FITC/PI apoptosis assay, and mitochondrial membrane potential (Δφm) measurement. The results of the research showed that ZnO‐NMts caused cytoplasmic vacuolization and nuclear pyknosis. After incubating cells with 12.5 µg mL−1 ZnO‐NMts for 12 h, ZnO NRfs exhibited the least toxicity and ROS levels. Additionally, there was a significant increase in caspase‐3 activity, depolarization of mitochondrial membrane potential (Δφm), and the highest rate of early apoptosis.This study successfully identified ZnO NRfs with the lowest toxicity and determined the safe exposure limit to be < 12.5 µg mL−1 (12 h). These findings will contribute to the clinical use of ZnO NRfs with low toxicity and provide a foundation for further research on their potential applications in brain disease treatment.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Screening of low‐toxic zinc oxide nanomaterials and study the apoptosis mechanism of NSC‐34 cells

Li,

Lu,

et al. 2024

Biotechnology Journal

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“…Time gaps between the initial stimuli and the later triggering stimuli therefore require information storage and maintenance. 14 , 16 The presence of memory has been reported not only in plants but for a broad range of taxa that includes microbes, 17 , 18 invertebrates 19 and vertebrates. 20 Memory storage for organisms that possess complex nervous systems is heavily based on specialized sites of cell–cell contact (connecting nerve cells within the nervous system), synapses and their change within.…”

Section: Memory Formationmentioning

confidence: 99%

Vegetal memory through the lens of transcriptomic changes – recent progress and future practical prospects for exploiting plant transcriptional memory

Farkas,

Dobránszki

2024

Plant Signaling & Behavior

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Plant memory plays an important role in the efficient and rapid acclimation to a swiftly changing environment. In addition, since plant memory can be inherited, it is also of adaptive and evolutionary importance. The ability of a plant to store, retain, retrieve and delete information on acquired experience is based on cellular, biochemical and molecular networks in the plants. This review offers an up-to-date overview on the formation, types, checkpoints of plant memory based on our current knowledge and focusing on its transcriptional aspects, the transcriptional memory. Roles of long and small non-coding RNAs are summarized in the regulation, formation and the cooperation between the different layers of the plant memory, i.e. in the establishment of epigenetic changes associated with memory formation in plants. The RNA interference mechanisms at the RNA and DNA level and the interplays between them are also presented. Furthermore, this review gives an insight of how exploitation of plant transcriptional memory may provide new opportunities for elaborating promising cost-efficient, and effective strategies to cope with the ever-changing environmental perturbations, caused by climate change. The potentials of plant memory-based methods, such as crop priming, cross acclimatization, memory modification by miRNAs and associative use of plant memory, in the future’s agriculture are also discussed.

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Dynamic responses of Salmonella Typhimurium to re-exposure to sublethal ciprofloxacin

Yi,

Kim,

Ahn

2024

FEMS Microbiology Letters

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This study was designed to evaluate the history-dependent behaviors of Salmonella Typhimurium re-exposed to sublethal levels of ciprofloxacin. The S. Typhimurium cells were pre-exposed to 0 (CON), 1/16 (LOW), 1/8 (MED), and 1/4 (HIGH) MICs of ciprofloxacin, followed by re-exposure to the same concentrations. The bacterial growth, post-antibiotic effect (PAE), relative fitness, and swimming motility of treatments were evaluated in the absence of ciprofloxacin. The lag phase duration (LPD) was estimate to assess bacterial recovery under ciprofloxacin exposure. A disk diffusion assay was used to determine the cross-resistance and collateral sensitivity of CON, LOW, MED, and HIGH treatments to ciprofloxacin (CIP), ceftriaxone (CEF), erythromycin (ERY), gentamicin (GEN), and polymyxin B (POL). The S. Typhimurium cells pre-exposed to ciprofloxacin were susceptible in antibiotic-free media, showing delayed growth. The highest PAE (> 1 h) and bacterial fluctuation (CV = 5%) were observed at the High treatment compared to the CON. The HIGH treatment had the lowest relative fitness levels (0.87) and swimming motility (55 mm). The LPD was significantly decreased at the LOW treatment (1.8 h) when re-exposed to 1/16× MIC of ciprofloxacin. The LOW, MED, and HIGH treatments showed the cross-resistance to POL and the collateral sensitivity to CEF, ERY, and GEN. The pre-exposure to ciprofloxacin could induce phenotypic diversity, corresponding to the history-dependent behaviors. These results provide important insights for the dynamic nature of bacterial populations when re-exposed to sublethal concentrations of antibiotics.

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Bacterial memory in antibiotic resistance evolution and nanotechnology in evolutionary biology

Cited by 5 publications

References 99 publications

Screening of low‐toxic zinc oxide nanomaterials and study the apoptosis mechanism of NSC‐34 cells

Screening of low‐toxic zinc oxide nanomaterials and study the apoptosis mechanism of NSC‐34 cells

Vegetal memory through the lens of transcriptomic changes – recent progress and future practical prospects for exploiting plant transcriptional memory

Dynamic responses of Salmonella Typhimurium to re-exposure to sublethal ciprofloxacin

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