Bacterial pathogens and their antimicrobial susceptibility in Otukpo Benue state of Nigeria

Okwori, EE; Nwadioha, S. I.; Nwokedi, Emmanuel; Odimayo, M. S.; Jombo, Gta

doi:10.1016/s2221-1691(11)60167-6

Cited by 4 publications

(3 citation statements)

References 6 publications

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“…The majority of the bacterial isolates 75.2 %, observed in the study were Gram negative bacilli mainly of the Enterobacteriaceae. This is in agreement with the reports of other researchers [12]. E. coli (30.5 %) was the most frequently isolated.…”

Section: Discussionsupporting

confidence: 93%

Antibiotic Susceptibility Pattern of Extended Spectrum Betalactamase (ESBL) Producers and other Bacterial Pathogens in Kano, Nigeria

Nwankwo¹,

Magaji²,

Tijjani³

2015

Trop. J. Pharm Res

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Section: Discussionsupporting

confidence: 93%

Antibiotic Susceptibility Pattern of Extended Spectrum Betalactamase (ESBL) Producers and other Bacterial Pathogens in Kano, Nigeria

Nwankwo¹,

Magaji²,

Tijjani³

2015

Trop. J. Pharm Res

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“…An older study by Umeh and Agbulu [14] reported a prevalence of 35.8%. Okwori et al [15] reported a prevalence rate of 56.8% in blood and stool of patients who attended General Hospital Otukpo between 1987 to 2000, with high resistance to chloramphenicol (49%), gentamicin (49%), ceftriaxone (25%) and ciprofloxacin (19%). Despite the increase in the prevalence of the disease in the study area, very little appears to be known about the susceptibility pattern of S. typhi.…”

Section: Introductionmentioning

confidence: 99%

Chloramphenicol is re-emerging as an effective drug in the treatment of typhoid fever in Southern Benue state, Nigeria

Adikwu

Ogbonna

Obande

et al. 2022

Microbes and Infectious Diseases

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“…In sub Saharan Africa, some studies reported resistance of Escherichia coli and Klebsiella pneumonia to Ampicillin averaged 75.4% and 97% of strains respectively, while a third of these organisms were reported to be resistant to Amoxicillin + Clavulanic acid [Adjei et al 2012] [16,17,18,19,20,21,22].…”

Section: Introductionmentioning

confidence: 99%

Bacterial Resistance to Commonly Prescribed Antibiotics in a Tertiary Care Hospital: A Retrospective Review of Evidence

Paul

Abdulateef

2019

JAMB

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Background: Antibiotic resistance is a growing global healthcare challenge and efforts to contain it are being outpaced by rapid emergence of resistant microbes. Common environmental pathogens have been reported to be manifesting resistance to several antibiotics to which they were once sensitive. In hospital setting, close contact between patients and caregivers allow resistant strains to easily spread in hospital wards. Evidence of antibiotic resistance is needed to inform rational selection of drugs for infectious diseases. Aim: The aims of this study were to determine common pathogenic bacterial isolates among patients and their antibiotic sensitivity profiles. Methods: This was a cross sectional retrospective study using laboratory records of antibiotic resistance profiles of bacterial isolates obtained from patient medical samples. Antibiogram records for one year period were obtained and relevant data extracted for analysis Results and Discussion: The most commonly isolated bacteria included Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae which together accounted for over two thirds of all isolates. Most of the isolates were resistant to at least four antibiotics; Penicillins, Sulphonamides and Tetracyclines exhibited the highest level of resistance. Resistance to these antibiotics is well reported in literature and their empirical prescription threatens their efficacy in the management of infectious diseases. Conclusion: Antibiotic resistance among pathogenic bacteria was high, there is need to emphasize evidence based prescriptions to not only improve clinical outcomes but also to preserve the efficacy of current antibiotic stock.

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Bacterial pathogens and their antimicrobial susceptibility in Otukpo Benue state of Nigeria

Cited by 4 publications

References 6 publications

Antibiotic Susceptibility Pattern of Extended Spectrum Betalactamase (ESBL) Producers and other Bacterial Pathogens in Kano, Nigeria

Antibiotic Susceptibility Pattern of Extended Spectrum Betalactamase (ESBL) Producers and other Bacterial Pathogens in Kano, Nigeria

Chloramphenicol is re-emerging as an effective drug in the treatment of typhoid fever in Southern Benue state, Nigeria

Bacterial Resistance to Commonly Prescribed Antibiotics in a Tertiary Care Hospital: A Retrospective Review of Evidence

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