Bacterial pneumonia in HIV-infected patients: a prospective study of 68 episodes

Falcó, Vicenç; Sevilla, Tomàs Fernández de; Alegre, José; Barbé, Jordi; Ferrer, Adelaida; Ocaña, Inmaculada; Ribera, Esteban; Jm, Martínez-Vázquéz

doi:10.1183/09031936.94.07020235

Cited by 46 publications

(13 citation statements)

References 26 publications

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“…Finally, ours is only the second study to report a direct comparison of the etiology of CAP in substantial numbers of hospitalized HIV-negative and HIV-positive patients [15]. Thus, our data help to place in perspective the results from a small and heterogeneous group of prospective studies of CAP etiology in various HIV-positive cohorts [36][37][38][39][40][41][42][43] and from a larger number of retrospective series of HIV-positive patients with CAP.…”

Section: Discussionmentioning

confidence: 68%

The Etiology of Community‐Acquired Pneumonia at an Urban Public Hospital: Influence of Human Immunodeficiency Virus Infection and Initial Severity of Illness

et al. 2001

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In a prospective study, the etiology of community-acquired pneumonia (CAP) was investigated among consecutive patients admitted to an academic, urban public hospital in Seattle. The study population was uniquely young, was predominantly male, and had high rates of homelessness, cigarette smoking, alcoholism, injection drug use, and human immunodeficiency virus (HIV) infection. Leading causes of CAP among HIV-negative patients were aspiration, followed by Streptococcus pneumoniae, Legionella species, and Mycoplasma pneumoniae. Among HIV-positive patients, Pneumocystis carinii, Mycobacterium tuberculosis, S. pneumoniae, and M. pneumoniae were the most common etiologic agents. Severe CAP was associated with typical bacterial infections and aspiration pneumonia but not Legionella infection among HIV-negative patients and with Pseudomonas aeruginosa infections among HIV-positive patients. These findings emphasize the need to tailor empirical antibiotic therapy according to local patient populations and individual risk factors and highlight the importance of recognizing underlying HIV infection in patients who are hospitalized with CAP.

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Section: Discussionmentioning

confidence: 68%

The Etiology of Community‐Acquired Pneumonia at an Urban Public Hospital: Influence of Human Immunodeficiency Virus Infection and Initial Severity of Illness

et al. 2001

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“…As it is in the general population, Streptococcus pneumoniae is the most common cause of bacterial pneumonia among HIV-infected adults, who have rates of bacteremia that are higher than those observed in non-HIV-infected subjects [3][4][5][6].…”

mentioning

confidence: 98%

Effectiveness of Polysaccharide Pneumococcal Vaccine in HIV-Infected Patients: a Case-Control Study

Peñaranda

Falcó

Payeras

et al. 2007

Clinical Infectious Diseases

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“…HIV-positive patients show greater susceptibility to bacterial pneumonia than the general population [3] with a more severe clinical evolution and a higher rate of bacteraemia than the noninfected population [7,15,16]. PPE is not an uncommon complication of bacterial pneumonia, and its frequency depends largely on its causative microorganism [17].…”

Section: Discussionmentioning

confidence: 99%

Parapneumonic effusions secondary to community-acquired bacterial pneumonia in human immunodeficiency virus-infected patients

Suay¹,

Cordero²,

Martínez³

et al. 1995

Eur Respir J

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The purpose of this study was to determine whether the clinical and microbiological characteristics of parapneumonic effusions in patients with community-acquired pneumonia (CAP) infected with the human immunodeficiency virus (HIV) were different from those observed in patients without HIV infection. One hundred and thirty seven patients with parapneumonic effusions were included and divided into two groups depending on whether they had HIV infection or not. The parapneumonic effusion rate was significantly higher in HIV-positive than in noninfected patients (21 vs 13%). Their clinical course was more severe, presenting a higher rate of bacteraemias (58 vs 18%). Pleural fluid in patients infected with HIV had significantly lower glucose levels than that of patients without HIV infection. Chest tube drainage was more frequent in parapneumonic effusions of patients infected with HIV than in those without HIV infection (71 vs 44%). Staphylococcus aureus was the most common microorganism found in the bacteriological samples of patients with CAP infected with HIV (53 vs 12%). We conclude that patients with community-acquired pneumonia and HIV infection have a higher rate of parapneumonic effusions and a more severe clinical course than non-HIV patients, and that Staphylococcus aureus predominates in their bacteriological samples.

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Bacterial pneumonia in HIV-infected patients: a prospective study of 68 episodes

Cited by 46 publications

References 26 publications

The Etiology of Community‐Acquired Pneumonia at an Urban Public Hospital: Influence of Human Immunodeficiency Virus Infection and Initial Severity of Illness

The Etiology of Community‐Acquired Pneumonia at an Urban Public Hospital: Influence of Human Immunodeficiency Virus Infection and Initial Severity of Illness

Effectiveness of Polysaccharide Pneumococcal Vaccine in HIV-Infected Patients: a Case-Control Study

Parapneumonic effusions secondary to community-acquired bacterial pneumonia in human immunodeficiency virus-infected patients

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