Bacterial Profile and Antibiotic Sensitivity Pattern of Csom Patient in Mewat Region

Abstract

The purpose of the present study was to determine the microbiological profile and antimicrobial susceptibility pattern of isolates from discharge in CSOM. MATERIAL AND METHODS This study included a total of 187 patients of CSOM with unilateral or bilateral discharge attending department of ENT in SHKM Govt. Medical College and Hospital Nalhar, Mewat, Haryana March 2015 to August 2015. Samples were inoculated on blood and Mac Conkey agar for 24-48hrs and identification of organism was done by using standard biochemical reactions and antibiotic susceptibility testing done by using modified Kirby Bauer method as per CLSI guidelines. RESULT Among 187 patients included in the study, most of the patients were between age group 11-20 years. CSOM was found to be more common in female patients (52%) than in male (48%) patients. The most common organisms were: Staphylococcus aureus (36%); Pseudomonas aeruginosa (34%); Klebsiella species, (6%) Proteus species (5%); Escherichia coli (4%); and other bacteria like Coagulase negative Staphylococcal species; Citrobacter spp, Enterobacter spp,Enterococcus spp,. According to antimicrobial susceptibility testing, Staphylococcus aureus was more sensitive to ciprofloxacin and gentamycin. Majority of gram negative isolates were sensitive to imipenem, quinolones and amikacin. CONCLUSION Result of our study showed high prevalence and resistance rate of Staphylococci and Pseudomonas isolates from CSOM patients to ß-lactam and other commonly used antimicrobials. Our study suggested that Amikacin, Piperacillin-Tazobactam and quinolones are best choice in these cases. Therefore an appropriate knowledge of antibacterial susceptibility of microorganism may contribute to rational antibiotic use and the success of treatment for CSOM.

Isolation, Identification of Bacterial Species Causing Chronic suppurative Otitis Media and Detection Some of Their Virulence Factors

“…E. cloacae represented the least common isolated bacterial species (1%), as table (4) shows. Similar Species of bacteria organisms were also isolated in various studies to CSOM [19,20] The results agree with the study of [3,21] where they point out that S. aureus and P. aeruginosa are the most common bacterial species in CSOM.…”

Bacterial Aetiology and their Antibiotic Susceptibility Pattern of Otitis Media in Paediatric Age Group

“…This susceptibility profile of isolated bacteria provides an evidence for bacterial resistance to many antimicrobial agents by means of multiple drug resistance (MDR), this can be noticed clearly from the susceptibility pattern of P. aeruginosa and S. aureus and increased frequency of Cefoxitin resistance S. aureus (MRSA) (5.8%) and this detection of multidrug resistant isolates may further limit therapeutic options. However, there are reports from different parts of the world with high resistance to this antimicrobial agents (Naz et al, 2015;Prakash et al, 2013;Habibu et al, 2015) Pseudomonas to be the most commonly isolated organisms may be that it can grow well in the absence of special nutrition, it proliferates at room temperature and it is highly resistant to antibiotics, making it difficult to treat. Pseudomonas is ubiquitous in our physical environment and has a predilection for the moist areas.…”

Extended spectrum beta lactamase producing bacteria among outpatients with ear infection at FelegeHiwot Referral Hospital, North West Ethiopia

“…In India 18.3–74.2% rate of ear infection with ESBL producing organisms have been reported [ 16 ].Similarly, in Nigeria and Tanzania, 8.3% and 16.3% ESBL producing GNB were isolated from ear swab samples, respectively [ 17 , 18 ].In Ethiopia there are no data on ear infection with ESBL producing bacteria. However, 38.4–57.6% rate of ESBL producing isolates were documented from other clinical and environmental samples [ 13 , 19 , 20 ].Repeated use of antibiotics, chronic disease, prolonged hospitalization, poor hygiene, inadequate health care, recurrent upper respiratory tract infections and overcrowding are frequently documented factors associated with ear infection [ 21 – 25 ].…”