Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study

Abstract

Background: Hospital acquired infections (HAIs) are one of the global concerns in resource limited settings. The aim of the study was to determine bacteria profile and their antimicrobial susceptibility patterns among patients admitted at surgical and medical wards.
 Methods: A hospital based cross-sectional study was conducted from November 2016 to July 2017 in MaddaWalabu Uni- versity Goba Referral Hospital. Urine and wound swabs were processed and standard disk diffusion test was done to assess susceptibility pattern. Association among variables was determined by Chi-square test.
 Results: Among 207 patients enrolled, 24.6% developed HAI, of which, 62.7% and 37.3% were from surgical and medical wards, respectively. The male to female ratio was 1.5:1. The age ranged from 19 to 74 years with a mean of 41.65(±16.48) years. A total 62 bacteria were isolated in which majority of the isolates were gram negative bacteria. Most isolates were re- sistance to most of the antibiotics tested but sensitive to Ceftriaxone, Norfloxacin and Ciprofloxacin.
 Conclusion: Due to the presence of high level drug resistant bacteria, empirical treatment to HAI may not be effective. Therefore, treatment should be based on the result of culture and sensitivity.
 Keywords: Antimicrobial susceptibility patterns; bacterial profile; hospital acquired infections.

Detection of multidrug-resistant organisms of concern including Stenotrophomonas maltophilia and Burkholderia cepacia at a referral hospital in Kenya

“…This was mainly due to the sharp increase in motorcycle accidents in Kenya, which mainly affects males [ 22 ]. Gram-negative bacteria were the more dominant isolates similar to other studies conducted in Africa [ 21 , 23 ]. Overall, coagulase-negative Staphylococci were the most isolated bacterial isolates, comparable to other studies that indicate CONS as the most commonly isolated microorganisms in clinical settings [ 24 ].…”

Detection of multidrug resistant organisms of concern includingS. maltophiliaandB. cepaciaat a referral hospital in Kenya

“…Among the positive samples, those associated with females were less than those from male's contrary to other studies which demonstrated more samples from females than males (20). This was mainly due to the sharp increase in motor cycle accidents in Kenya, which mainly affects males (21). Gram-negative bacteria were the more dominant isolates similar to other studies conducted in Africa (20) (22).…”

Bacterial Profile and Their Antimicrobial Susceptibility Pattern of Isolates Recovered from Intensive Care Unit Environments at Wachemo University Nigist Ellen Mohammed Memorial Comprehensive Specialized Hospital, Southern Ethiopia

“…Tis recognized prevalence of GPB might be due to the bacterial resistance ability to dry conditions of the hospital environment and transmission from skin, nasal, and hands of health care providers and patients, and also the presence of underlying clinical conditions and immunocompromised patients admitted to intensive care. From Gram-negative isolates, E. coli 41 (39%) was highly isolates from the all study groups in these output, but it contradicts with the fndings of the study in Namibia 24% [30], Gondar 16.3%, [34], Madda-Walabu 20.9% [39], Mizan-Tepi 11.4% [36], Gondar [34], Northern Nigeria 8.0% [40], Mekelle 0.8%, [27] and Hiwot Fana 7.3% [41]. Tis could be explained by existence of colonized/infected patients in the ICU environments of the hospital, or failure of routine cleaning and disinfection practices.…”