Bactericidal and Fungicidal Properties of Some Antiseptic Drugs and Disinfectants

Гунар, О. В.; Dorenskaya, A. V.; Булгакова, Г. М.; Sakhno, N. G.

doi:10.1007/s11094-022-02720-0

Cited by 2 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results was in accordance to Gunar et al 36 who showed that alcohol was not effective in killing all fungal species on contrast ,they reported that sodium hypochloride was most effective within a maximum of 3 min contact time.…”

Section: Disinfectants Efficacy On Environmental Fungisupporting

confidence: 93%

Characterization of Nosocomial Fungal Infection among Hepatic ICU Patients in National Liver Institute

Ghoneim,

Abd ElAziz,

Awad

et al. 2024

Egyptian Journal of Medical Microbiology

View full text Add to dashboard Cite

Background: Fungi now represent a serious worldwide threat especially in patients with comorbidities as liver diseases with association of high mortality rates. Regular assessment of at-risk patients, diagnosis by reliable methods in addition to knowledge about antifungal susceptibility and possible sources of such infection help to contain the spread of those life threating infections among high-risk hepatic ICU patients. Objective: Determination of the incidence, morbidity and mortality of nosocomial fungal infection in hepatic ICU patients, determination of the possible risk factors and antifungal susceptibility pattern in them, tracing possible sources of infection and finally assessment available disinfectants against fungi. Methodology: The study was conducted on 150 hepatic ICU patients after 48 th hours from admission and also on their related environment. Fungal cultures and Multiplex PCR were done for isolation and species identification of the isolates and antifungal susceptibility and antifungal bio typing of suspected sources of infection were performed by VITEK 2 YST-AST cards and disc diffusion method different disinfectants were tested by sampling surfaces before and after disinfection. Results: The incidence of NFI among hepatic ICU patients was (23.3%) with high mortality (69%). The most significant risk factors were the presence of CVC, prolonged ICU stay, COVID infection, previous fungal colonization, antibiotics and corticosteroid exposure and total parenteral nutriton. The most predominant species were C.albicans (43%) with rising incidence of Non albicans (57%).Antifungal susceptibilities were variable with increasing incidence of Azoles resistance. HCWs hands were the most common source of infection (58%). Lysoformine and Chlorine were effective against environmental fungi (100% reduction).Conclusion: NFI are obvious threat to hepatic ICU patients with high incidence and high mortality rates which is needed to be early diagnosed specifically to species level for proper antifungal targeting. Proper hand hygiene and environmental cleaning are the corner stone of prevention.

show abstract

Section: Disinfectants Efficacy On Environmental Fungisupporting

confidence: 93%

Characterization of Nosocomial Fungal Infection among Hepatic ICU Patients in National Liver Institute

Ghoneim,

Abd ElAziz,

Awad

et al. 2024

Egyptian Journal of Medical Microbiology

View full text Add to dashboard Cite

show abstract

“…To do this, substances with an antimicrobial effect must meet several following requirements: -they must have a wide spectrum of antimicrobial action, that is, effectively destroy bacteria, mycobacteria, viruses, fungi, and spores, regardless of the duration and frequency of use, ensuring that these preparations have properties that prevent the development of resistance in microorganisms; -the preparations should not harm humans and animals, both during their preparation and application and after the end of their purposeful use, that is, during the period of degenerative and destructive changes caused by environmental factors or biodegradation processes in the human body. In other words, antimicrobial substances and products of their natural or artificial degradation should not contain xenobiotic substances; -the antimicrobial substance should have a washing capacity with the least damaging and corrosive activity concerning various materials and be as easy to use and relatively cheap (Gunar et al, 2022;Lee et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the antibacterial effect of Artemisia lerchiana compared with various medicines

Nametov,

Yertleuova,

Orynkhanov

et al. 2023

Braz. J. Biol.

View full text Add to dashboard Cite

Many antimicrobial substances, mainly of chemical origin, are not effective and reliable. Many of them tend to accumulate in organs and tissues and have allergic and toxicological effects and side effects. Therefore, the purpose of our research was to conduct a comparative analysis of the antibacterial effect of Artemisia lerchiana against other herbal preparations. A. lerchiana was used in the form of an infusion and essential oil extract to fulfill the set goal and objectives. For comparative analysis, tinctures of A. absinthium, Calendula officinalis L., and Chamomilla recutita L., as well as preparations based on Abies Sibirica, Eucalyptus, Limon, Bergamottae, Melaleuca alternifolia, and A. absinthium essential oils were used. As a test standard for comparing antibacterial properties, we used the Septarius chemical preparation manufactured at a biofactory. The experiment was carried out in vitro using test microbes of gram-positive Staphylococcus aureus and Streptococcus and gram-negative Escherichia coli. The results of the study showed that A. lerchiana had a high antibacterial effect against gram-positive test microbes (Staphylococcus, Streptococcus). The most effective form was A. lerchiana in the form of essential oil, which had an antibacterial effect even in low concentrations. A comparative assessment of A. lerchiana with the Septarius test antiseptic showed that A. lerchiana had a similar effect in general. In the form of essential oil, it even surpassed the effect of Septarius. It was found that A. lerchiana surpassed medicinal plants used in the experiment in terms of antibacterial effect. The obtained results of the study will be useful for scientists researching various medicinal products of plant origin and for veterinary specialists looking for therapeutic and preventive measures.

show abstract

Bactericidal and Fungicidal Properties of Some Antiseptic Drugs and Disinfectants

Cited by 2 publications

References 1 publication

Characterization of Nosocomial Fungal Infection among Hepatic ICU Patients in National Liver Institute

Characterization of Nosocomial Fungal Infection among Hepatic ICU Patients in National Liver Institute

Evaluation of the antibacterial effect of Artemisia lerchiana compared with various medicines

Contact Info

Product

Resources

About