Bactericidal laser ablation of carbon dots: An in vitro study on wild-type and antibiotic-resistant Staphylococcus aureus

Sattarahmady, N.; Rezaie-Yazdi, M.; Tondro, G.H.; Akbari, Neda

doi:10.1016/j.jphotobiol.2016.12.006

Cited by 58 publications

(29 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, bacteria have a multitude of mechanisms by which they can rapidly acquire resistance [ 1 , 2 ], which is of particular concern for high-risk populations such as those in healthcare settings [ 3 , 4 ]. For those with concurrent conditions, such as cancer, bacterial infections can severely worsen patient health [ 5 , 6 ]; infections may also delay wound recovery even when treated, with some negative health impacts associated with current disinfection techniques [ 7 ]. These cumulative effects place a premium on developing techniques to mitigate the threat of infection from deadly pathogens, namely by improved sterilization technologies.…”

Section: Introduction: Photodynamic Antimicrobial Therapy and Carbmentioning

confidence: 99%

Carbon Nanodots in Photodynamic Antimicrobial Therapy: A Review

Knoblauch

Geddes

2020

Materials

View full text Add to dashboard Cite

Antibiotic resistance development in bacteria is an ever-increasing global health concern as new resistant strains and/or resistance mechanisms emerge each day, out-pacing the discovery of novel antibiotics. Increasingly, research focuses on alternate techniques, such as antimicrobial photodynamic therapy (APDT) or photocatalytic disinfection, to combat pathogens even before infection occurs. Small molecule “photosensitizers” have been developed to date for this application, using light energy to inflict damage and death on nearby pathogens via the generation of reactive oxygen species (ROS). These molecular agents are frequently limited in widespread application by synthetic expense and complexity. Carbon dots, or fluorescent, quasi-spherical nanoparticle structures, provide an inexpensive and “green” solution for a new class of APDT photosensitizers. To date, reviews have examined the overall antimicrobial properties of carbon dot structures. Herein we provide a focused review on the recent progress for carbon nanodots in photodynamic disinfection, highlighting select studies of carbon dots as intrinsic photosensitizers, structural tuning strategies for optimization, and their use in hybrid disinfection systems and materials. Limitations and challenges are also discussed, and contemporary experimental strategies presented. This review provides a focused foundation for which APDT using carbon dots may be expanded in future research, ultimately on a global scale.

show abstract

Section: Introduction: Photodynamic Antimicrobial Therapy and Carbmentioning

confidence: 99%

Carbon Nanodots in Photodynamic Antimicrobial Therapy: A Review

Knoblauch

Geddes

2020

Materials

View full text Add to dashboard Cite

show abstract

“…The developed material exhibited good fluorescence emission for simultaneous detection and inhibition of Gram-positive bacteria. Sattarahmady et al [24] demonstrated that the bactericidal effect of CDs can be accelerated by near infrared (NIR, 808 nm) irradiation. The NIR irradiation caused an increase of the solution temperature, inducing ROS production and cell wall damage.…”

Section: Introductionmentioning

confidence: 99%

Enhanced antibacterial activity of carbon dots functionalized with ampicillin combined with visible light triggered photodynamic effects

Jijie

Barras

Bouckaert

et al. 2018

Colloids and Surfaces B: Biointerfaces

128

View full text Add to dashboard Cite

In the last years, carbon-based nanomaterials have attracted considerable attention in a wide range of fields, particularly in biomedicine, owing to their remarkable photo-physical and chemical properties. In this study, we demonstrate that amine-terminated carbon dots (CDs-NH) functionalized with ampicillin (AMP) offer a new perspective for antibacterial treatment. The amine-functionalized carbon dots were used as a carrier for immobilization and delivery of ampicillin (CDs-AMP) and as a visible light-triggered antibacterial material. Additionally, AMP immobilization on the CDs-NH surface improves its stability in solution as compared to free AMP. The AMP conjugated CDs platform combines the antibacterial function of AMP and conserves the intrinsic theranostic properties of CDs-NH. Therefore, the AMP immobilized onto CDs-NH surface together with the generation of moderate quantities of reactive oxygen species under visible light illumination are very effective to inactivate the growth of Escherichia coli.

show abstract

“…Nanomaterials show novel biological and physicochemical properties in comparison with the bulk of counterparts [1,2]. A large number of physicochemical and green approaches used to synthesise different nanostructures of carbon, noble metals, and transition metal oxides [3][4][5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Copper/copper oxide nanoparticles synthesis usingStachys lavandulifoliaand its antibacterial activity

Khatami

Heli

Jahani

et al. 2017

IET nanobiotechnol.

View full text Add to dashboard Cite

Nanoparticles of copper/cuprous oxide (Cu/Cu 2 O) were successfully synthesised by a green chemistry route. The synthesis process was carried out using an extract of Stachys lavandulifolia as both reducing and capping agents with a facile procedure. The nanoparticles were characterised by different techniques including X-ray diffraction, indicating that the synthesised sample comprised both copper and cuprous oxide entity. The nanoparticles had a mean size of 80 nm and represented an impressive bactericidal effect on Pseudomonas aeruginosa.

show abstract

Bactericidal laser ablation of carbon dots: An in vitro study on wild-type and antibiotic-resistant Staphylococcus aureus

Cited by 58 publications

References 51 publications

Carbon Nanodots in Photodynamic Antimicrobial Therapy: A Review

Carbon Nanodots in Photodynamic Antimicrobial Therapy: A Review

Enhanced antibacterial activity of carbon dots functionalized with ampicillin combined with visible light triggered photodynamic effects

Copper/copper oxide nanoparticles synthesis usingStachys lavandulifoliaand its antibacterial activity

Contact Info

Product

Resources

About