Bactericidal properties of experimental dental composites based on dimethacrylate resins reinforced by nanoparticles

Properties of Experimental Dental Composites Containing Antibacterial Silver-Releasing Filler

“…Increasing antibacterial filler concentration caused a small but systematic lowering of microhardness. This is in opposition to some findings for commercially available materials, where higher filler content was correlated with higher microhardness [ 117 ], but is in accordance with some research, where introducing antibacterial additives decreased microhardness [ 44 , 101 , 111 ].…”

“…The reduction of microorganisms was noted, however, only when the experimental filler was added into the matrix and its concentration was limited to 10%, so those interesting results needs confirmation in follow-up experiments on materials with typical reinforcing fillers. Łukomska-Szymańska et al [ 44 ], reported a viability of S. mutans from 48% to 87% in comparison to control samples on the surface of experimental composites with the addition of silver particles alone and combined titanium dioxide, silica dioxide, and zirconium dioxide nanoparticles or microparticles. Kasraei et al [ 37 ] and Azarsina et al [ 45 ] modified commercially available composites with silver nanoparticles and noted a reduction of bacterial colonies.…”

“…Kasraei et al [ 37 ] and Azarsina et al [ 45 ] modified commercially available composites with silver nanoparticles and noted a reduction of bacterial colonies. However, amber to brown discoloration of materials with nanosilver has been noted, which is a limitation for an esthetic material [ 37 , 44 , 45 ]. Also, the inhibitory effect against S. mutans of resin composites with silver-containing inorganic particles like silica gel have been confirmed, which the authors linked not with silver ion release but with the presence of active oxygen, including hydroxyl radicals, created by the catalytic action of silver during photoactivation or contact with water at polar surfaces [ 46 ].…”

Effect of Storage in Distilled Water for Three Months on the Antimicrobial Properties of Poly(methyl methacrylate) Denture Base Material Doped with Inorganic Filler

“…, fungi or bacteria). The comparative effectiveness of the studied materials has yet to be determined using different microbiological tests, such as live/dead cell viability assays [ 35 ], where the surface colonization of the samples is analyzed using fluorescence microscopy because the filler-free areas may potentially be colonized. However, for samples with low microorganism SR values in the environment, the viability of microorganisms on the material surface should also be very low.…”