Bacteriocin-like activity of Bacteriodes fragilis group isolated from marmosets

Farias, Luiz M.; Carvalho, Maria Auxiliadora Roque de; Damasceno, Carlos Américo Veiga; Cisalpino, E. O.; Vieira, Eliane

doi:10.1016/0923-2508(92)90004-8

Cited by 12 publications

(10 citation statements)

References 33 publications

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“…These data are similar to those reported by Farias et al (8). Bacteriophages were not observed since the inhibitory action was not transmissible as shown by the tested method (26), excluding the possibility of phages causing the bacteriocin-like effect have been suggested by several authors (14,20).…”

Section: Discussionsupporting

confidence: 81%

“…In some Gram-negative bacteria, such as Pseudomonas solanacearum and B. fragilis, this phenomenon has not been observed (7,8,16). Our results show auto-inhibition in 18.4 % and 25 % of the periodontal and healthy isolates, respectively.…”

Section: Discussionsupporting

confidence: 51%

“…Because bacteriocin-like substances are produced by a high number of oral microorganisms, a constant and complex intra-or inter-specific regulation can be expected (8).…”

Section: Discussionmentioning

confidence: 99%

“…Plates were incubated at 37 o C for 72 h under anaerobic conditions (10% CO 2 / 90% N 2 ). After incubation, the cells were killed by exposure to chloroform for 30 min (8).…”

Section: Bacteriocinogenic Activitymentioning

confidence: 99%

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Bacteriocin-like activity of oral Fusobacterium nucleatum isolated from human and non-human primates

Júnior¹,

Ávila-Campos²

1999

Rev. Microbiol.

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Fusobacterium nucleatum is indigenous of the human oral cavity and has been involved in different infectious processes. The production of bacteriocin-like substances may be important in regulation of bacterial microbiota in oral cavity. The ability to produce bacteriocin-like substances by 80 oral F. nucleatum isolates obtained from periodontal patients, healthy individuals and Cebus apella monkeys, was examinated. 17.5% of all tested isolates showed auto-antagonism and 78.8% iso-or hetero-antagonism. No isolate from monkey was capable to produce auto-inhibition. In this study, the antagonistic substances production was variable in all tested isolates. Most of the F. nucleatum showed antagonistic activity against tested reference strains. These data suggest a possible participation of these substances on the oral microbial ecology in humans and animals. However, the role of bacteriocins in regulating dental plaque microbiota in vivo is discussed.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionsupporting

confidence: 51%

“…Because bacteriocin-like substances are produced by a high number of oral microorganisms, a constant and complex intra-or inter-specific regulation can be expected (8).…”

Section: Discussionmentioning

confidence: 99%

“…Plates were incubated at 37 o C for 72 h under anaerobic conditions (10% CO 2 / 90% N 2 ). After incubation, the cells were killed by exposure to chloroform for 30 min (8).…”

Section: Bacteriocinogenic Activitymentioning

confidence: 99%

See 2 more Smart Citations

Bacteriocin-like activity of oral Fusobacterium nucleatum isolated from human and non-human primates

Júnior¹,

Ávila-Campos²

1999

Rev. Microbiol.

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“…In contrast, when the producer strain was grown in milk supplemented with yeast extract, a medium that favors macedocin production, no autoinhibition was observed. Autoantagonism was also described for strains of the Bacteroides fragilis group (15) and Fusobacterium spp. (42).…”

Section: Discussionmentioning

confidence: 99%

Macedocin, a Food-Grade Lantibiotic Produced by Streptococcus macedonicus ACA-DC 198

Georgalaki

Berghe

Kritikos

et al. 2002

Appl Environ Microbiol

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Streptococcus macedonicus ACA-DC 198, a strain isolated from Greek Kasseri cheese, produces a food-grade lantibiotic named macedocin. Macedocin has a molecular mass of 2,794.76 ؎ 0.42 Da, as determined by electrospray mass spectrometry. Partial N-terminal sequence analysis revealed 22 amino acid residues that correspond with the amino acid sequence of the lantibiotics SA-FF22 and SA-M49, both of which were isolated from the pathogen Streptococcus pyogenes. Macedocin inhibits a broad spectrum of lactic acid bacteria, as well as several food spoilage and pathogenic bacteria, including Clostridium tyrobutyricum. It displays a bactericidal effect towards the most sensitive indicator strain, Lactobacillus sakei subsp. sakei LMG 13558 T , while the producer strain itself displays autoinhibition when it is grown under conditions that do not favor bacteriocin production. Macedocin is active at pHs between 4.0 and 9.0, and it retains activity even after incubation for 20 min at 121°C with 1 atm of overpressure. Inhibition of macedocin by proteolytic enzymes is variable.

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Bacteriocin‐mediated interactions within and between coexisting species

Hawlena

Bashey

Lively

2012

Ecology and Evolution

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Bacteriocins are bacteriocidal toxins released by almost all bacteria. They are thought to have a narrow range of killing, but as bacteriocin-mediated interactions have been rarely studied at biologically relevant scales, whether this narrow range of action falls mostly within or mostly between coexisting species in natural communities is an open question with important ecological and evolutionary implications. In a previous study, we systematically sampled Xenorhabdus bacteria along a hillside and found evidence for genotypic variability and bacteriocin-mediated interactions within Xenorhabdus bovienii and X. koppenhoeferi colonies that were collected only a few meters apart. In contrast, colonies that were isolated from the same soil sample were always genetically similar and showed no inhibitions. Here, we conducted pairwise growth-inhibition assays within and between seven X. bovienii and five X. koppenhoeferi colonies that were isolated from different soil samples; all seven X. bovienii colonies and at least three of the X. koppenhoeferi have been distinguished as distinct genotypes based on coarse-grain genomic markers. We found signatures for both conspecific and heterospecific bacteriocin inhibitions in this natural community of Xenorhabdus bacteria, but intraspecific inhibitions were significantly more common than interspecific inhibitions. These results suggest that bacteriocins have a major role in intraspecific competition in nature, but also suggest that bacterocins are important in mediating interspecific interactions among coexisting species in natural communities.

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Bacteriocin-like activity of Bacteriodes fragilis group isolated from marmosets

Cited by 12 publications

References 33 publications

Bacteriocin-like activity of oral Fusobacterium nucleatum isolated from human and non-human primates

Bacteriocin-like activity of oral Fusobacterium nucleatum isolated from human and non-human primates

Macedocin, a Food-Grade Lantibiotic Produced by Streptococcus macedonicus ACA-DC 198

Bacteriocin‐mediated interactions within and between coexisting species

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