Bacteriological Evaluation and Their Antibiotic Sensitivity Pattern in Tonsillitis

Agrawal, Anand; Kumar, Dileep; Goyal, Ankur; Gupta, Ravi; Bhooshan, Suneel

doi:10.9790/0853-13355155

Cited by 15 publications

(24 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the study by Agrawal et al on all age group patients, common causative organisms isolated from the tonsillar surface were alpha-hemolytic Streptococci, Staphylococcus aureus, non-pathogenic Neisseria species, Haemophilus influenza, Pneumococcus, Enterococcus, Bacteroid fragilis, and Corynebacterium species. No anaerobes were identified [ 8 ]. In another study by Omer et al in Turkey, an attempt was made to isolate the facultative and obligate anaerobes from the surface and core of patients with recurrent tonsillitis [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Microbiological Profile of Chronic Tonsillitis in the Pediatric Age Group

Raja¹,

Subramanian

Vijayakumar

et al. 2018

Cureus

View full text Add to dashboard Cite

IntroductionTonsillitis is a very common disease in children. Understanding the microbiology and pathology of chronic tonsillitis is an important step in its management. The aim of the study was to describe the microbiological profile of core tonsillar tissue in chronic tonsillitis in children.Materials and methodsChildren under 16 years of age with chronic tonsillitis were recruited in the descriptive study. Children with recurrent tonsillitis and recurrent tonsillitis with obstructive symptoms were included. Children who underwent tonsillectomy for obstructive symptoms alone and those who received antibiotics for at least one month prior to surgery were excluded from the study. Dissection and the snare method of tonsillectomy were done on all children. The operated specimen was cut into two halves in a sterile container. The core of the tonsillar tissue was swabbed with two sterile cotton-tipped swabs and sent for the microbiological evaluation of aerobes and anaerobes. The tonsillar tissue was sent for a histopathological examination.ResultsA total of 106 children were operated for chronic tonsillitis in one year. The mean age of children included in this study was 9.4 years. The duration of symptoms due to tonsillar disease ranged from four weeks to 28 months. There were 48 males and 58 females. Recurrent tonsillitis was the most common indication for tonsillectomy in all children. A total of 301 aerobes and 171 anaerobic microorganisms were isolated from 106 children with chronic tonsillitis. The aerobic bacterial species most often isolated was Streptococcus viridans, which was present in 83 children followed by Group A, β-hemolytic Streptococci in 67 children. The anaerobic bacterial most often isolated was Peptococcus species in 49 children. Polymicrobial aerobic and anaerobic flora were present in all tonsillar specimens, yielding an average of 4.1 isolates per specimen. The histopathological examination revealed chronic tonsillitis with reactive follicular hyperplasia in all (100%) children. Actinomycosis was associated with non-specific reactive follicular hyperplasia in four specimens.ConclusionPolymicrobial aerobic and anaerobic flora are identified in deep tonsillar tissue in children with tonsillitis. The identification of bacterial isolates from the core tissue in recurrent tonsillitis could dictate the management of chronic tonsillitis. The histopathological examination of the core tissues of the tonsils helps in an accurate identification of organisms that are difficult to culture.

show abstract

Section: Discussionmentioning

confidence: 99%

Microbiological Profile of Chronic Tonsillitis in the Pediatric Age Group

Raja¹,

Subramanian

Vijayakumar

et al. 2018

Cureus

View full text Add to dashboard Cite

show abstract

“…In contrary the BabaiwaU.F et al 13 showed identical organism in both surface and core in maximum number of patients. Abdelaziz.M.E et al 14 showed variation in 62.5% cases and similarity in 37.5% and Agarwal.A et al 15 showed variation in surface and core organisms in 63.63% and similarity in 36.3%. This study showed that gentamycin, amikacin and ampiclox should be the treatment of choice for gram positive organisms, ciprofloxacin and sparfloxacin for the gram negative organisms (Table:9).…”

Section: Discussionmentioning

confidence: 96%

Chronic Tonsillitis: A Comparative Study of the Causative Organism Cultured Through Throat Swab vs. Core Culture and Biopsy of the Tonsillectomy Specimen

2016

IJSR

View full text Add to dashboard Cite

“…In Salman Mutiullah Shaikh et al, 13 the most common organism was Streptococcus pneumoniae (86.56%) followed by Staphylococcus aureus (47.76%). Bista M et al 9 showed Streptococcus viridans and Streptococcus pneumoniae and in Agarwal A et al 14 Streptococcus viridans and Branhamella catarrhalis (71.13%). So majority of tonsil core culture studies identified Staph.…”

Section: Methodsmentioning

confidence: 97%

A Study on Tonsil Core Culture in Chronic and Recurrent Tonsillitis

Shaik¹,

Krishna²,

Sayyad³

2018

jemds

View full text Add to dashboard Cite

BACKGROUND Palatine tonsils are the components of Mucosa Associated Lymphoid Tissue (MALT) of pharynx. Embryologically, they develop from second branchial arch and play an important role in immune system. These are lined by stratified squamous epithelium in continuation with pharyngeal mucosa. The surface epithelium of tonsil will invaginate to form crypts. These crypts contain cheesy material which constitute food debris, keratin and bacteria. Infection of tonsil, tonsillitis was a more common infection of humans. During tonsillitis, the bacteria inhabiting the crypts will multiply and secrete toxins. This inflammation of tonsil tissue will lead to WBC infiltration, finally leading to swollen and congested tonsils. Antibiotics play an important role in treatment of acute tonsillitis. Appropriate antibiotic selection from tonsil surface swab culture for an adequate duration will prevent the continuation and spread of infection. Contrary to this surface swab culture oriented antibiotic selection, few studies reported that the bacteria causing tonsillitis may also be present in deep tonsillar tissues. Hence, the organisms grown from tonsillar surface swab cultures may not be representative of actual infective organism always. MATERIALS AND METHODS This descriptive study was carried out as a prospective study among 60 patients who underwent tonsillectomy at a tertiary care hospital. Data was collected about various socio-demographic factors, clinical information and details about routine lab examinations. After tonsillectomy, the specimen was transferred in sterile water for aerobic culture and KOH mount. RESULTS Out of 33 positive cultures, S. aureus (48.5%) was grown majorly followed by H. influenzae (18.2%), S. pyogenes (12.1%), Pseudomonas (9.1%), K. pneumoniae (6.1%), S. pneumoniae (3%) and no fungal elements were detected. CONCLUSION Surface cultured microorganism represent more of normal commensals, which is a false indicator of the pathogen in the core. The findings of this study are in support of directing rational therapy against tonsillar core pathogens like Staph. aureus, H. influenza, Pseudomonas, Klebsiella with antibiotics like Gentamycin, Amikacin and Ciprofloxacin.

show abstract

Bacteriological Evaluation and Their Antibiotic Sensitivity Pattern in Tonsillitis

Abstract: The Study Was

Cited by 15 publications

References 10 publications

Microbiological Profile of Chronic Tonsillitis in the Pediatric Age Group

Microbiological Profile of Chronic Tonsillitis in the Pediatric Age Group

Chronic Tonsillitis: A Comparative Study of the Causative Organism Cultured Through Throat Swab vs. Core Culture and Biopsy of the Tonsillectomy Specimen

A Study on Tonsil Core Culture in Chronic and Recurrent Tonsillitis

Contact Info

Product

Resources

About