Bacteriological profile and antimicrobial susceptibility in surgical site infection in elective abdominal surgeries

Bansal, Dipika; Singh, Rana Ranjit; Kulwant, Singh; Aggarwal, Aruna; Puar, Gurlal Singh; Shah, Amip

doi:10.18203/2349-2902.isj20163559

Cited by 1 publication

(2 citation statements)

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“…28 29 Inefficacy of penicillin in S. aureus isolates has been reported in previous studies as well. 23 However, S. aureus isolates from this study did not show any resistance toward linezolid, vancomycin, and teicoplanin. This corroborates with other studies as well.…”

Section: Discussionmentioning

confidence: 52%

“…As against a previous study, diabetes mellitus was not associated with SSIs. 12,13,21 The predominance of gram-negative organisms, specifically E. coli, in the development of SSIs in the patient with abdominal surgeries has already been reported in many studies, [22][23][24][25][26] although few other studies have observed K. pneumoniae as the commonest gram-negative bacteria from the SSIs. 27 All the S. aureus isolates were found to be resistant to ampicillin, penicillin, and methicillin (MRSA), and a few were found (12.5%) susceptible to amoxycillin-clavulanate combination.…”

Section: Discussionmentioning

confidence: 94%

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Drug-Resistant Strains in Surgical Site Infections after Abdominal Surgery: A Prospective Study

Gupta,

Kaur,

Chhina

et al. 2022

Journal of Gastrointestinal Infections

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Background Surgical site infection (SSI) is a common complication of abdominal surgery associated with substantial discomfort, morbidity, and cost. Objective The aim of this study was to determine the incidence, risk factors, and antimicrobial susceptibility pattern of the associated bacterial causes of SSI in patients after abdominal surgery. Methods A prospective study over a 1-year (Jan 2019–Dec 2019) period was conducted at a tertiary care institution in North India. Postoperative patients of abdominal surgeries with SSI were included in the study. Any exudate from the surgical site was collected aseptically and was processed as per standard operating procedures. Results Of 2,509 patients with abdominal surgeries included in the study, 75 (2.98%, majority, i.e., 50 males) developed SSI. Common risk factors found to be associated with the development of SSI include contaminated surgical sites, obesity, age, immunosuppression, and simultaneous infection at some other sites, with a predominance (89.3%) of gram-negative isolates. Escherichia coli was the most frequently isolated organism (45.3%), followed by Klebsiella spp. (20%), Acinetobacter spp.(10.6%), Pseudomonas spp., and Staphylococcus aureus (8% each). There was a very high (53%) prevalence of extended-spectrum β lactamase production among the E. coli and Klebsiella isolates. Additionally, 58.8% of the E. coli isolates were multidrug-resistant, whereas 73.3% of the Klebsiella isolates were exclusively drug resistant. All the S. aureus isolates were found to be methicillin-resistant. Conclusion Although the SSI rates after abdominal surgery were low, multidrug-resistant gram-negative bacteria were predominant in SSI.

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Section: Discussionmentioning

confidence: 52%