Bacteriological study in perianal abscess is not useful and not cost‐effective

Xu, Roland Weixiang; Tan, Ker‐Kan; Chong, Choon Seng

doi:10.1111/ans.13630

Cited by 23 publications

(14 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, pathogen isolation from the perianal area was not done in any of the patients. Although Xu et al [21] suggest that bacteriological study of perianal abscesses may be not useful or cost-effective, more effort should be put into isolating pathogens from either the blood or perianal area in the future.…”

Section: Discussionmentioning

confidence: 99%

Perianal Infections in the Phase before Engraftment after Allogeneic Hematopoietic Stem Cell Transplantations: A Study of the Incidence, Risk Factors, and Clinical Outcomes

Xia

et al. 2018

Acta Haematol

View full text Add to dashboard Cite

In this study, we aimed to investigate the incidence, risk factors, and clinical outcomes of perianal infections during the pre-engraftment phase after allogeneic hematopoietic stem cell transplantation (allo-HSCT).Consecutive patients who underwent non-T-cell-depleted allo-HSCT at the Peking University Institute of Hematology from January 1 to December 31, 2016 were enrolled (n = 646). Ninety-nine patients were found to have perianal infections during the pre-engraftment phase, and 80 were found to have neutropenia on perianal infection diagnosis. The cumulative incidence of perianal infection during the pre-engraftment phase after allo-HSCT was 15.3%. A history of perianal infection (hazard ratio [HR] = 15.28, p < 0.001) or hemorrhoids before allo-HSCT (HR = 3.09, p = 0.001) was significantly associated with the new occurrence of perianal infection after allo-HSCT. All patients received empirical broad-spectrum antimicrobial therapies, and 97 were cured after treatment. The clinical outcomes at 100 days after allo-HSCT were comparable in patients with and without perianal infections.In summary, patients who had perianal infection or hemorrhoids before allo-HSCT had a higher risk of new occurrence of perianal infection after allo-HSCT. With appropriate treatment, perianal infection during the pre-engraftment phase did not influence the clinical outcomes.

show abstract

Section: Discussionmentioning

confidence: 99%

Perianal Infections in the Phase before Engraftment after Allogeneic Hematopoietic Stem Cell Transplantations: A Study of the Incidence, Risk Factors, and Clinical Outcomes

Xia

et al. 2018

Acta Haematol

View full text Add to dashboard Cite

show abstract

“…However, some studies suggest that the intestinal flora is not related to the occurrence of perianal abscess recurrence and anal fistula; thus, it is not necessary to cultivate it. 29 However, based on the results of existing pus cultures, antibiotics currently used mainly include β-lactam/β-lactamase inhibitors and nitroimidazoles. 9,16,22 The use of antibiotics without basis is likely to cause the production of drug-resistant bacteria, such as K. pneumoniae with high resistance to ampicillin and furantoin.…”

Section: Treatment Conservative Treatmentmentioning

confidence: 99%

Treatment of Perianal Abscess and Fistula in Infants and Young Children: From Basic Etiology to Clinical Features

Ding

Sun

2020

The American Surgeon™

View full text Add to dashboard Cite

Perianal abscess and anal fistula are 2 common anorectal diseases in infants and young children. However, their causes, clinical diagnosis, and treatment remain controversial. Compared to adults, infants with these 2 diseases exhibit unique clinical characteristics. Blind pursuit of conservative treatment or surgery may worsen the condition, resulting in increased pain in young patients and greater economic burden and psychological harm to parents. Therefore, it is crucial to select correct and effective treatments. This review summarizes the relevant literature from the past 10 years and systematically explains the pathogenesis, clinical characteristics, and treatment measures of perianal abscess and anal fistula in infants with the goal of providing clinicians a deeper understanding of perianal abscess and anal fistula in infants and summarizing safe and effective treatment methods.

show abstract

“…18 However, a recent case series of 164 patients found no statistically significant association between the presence of gut-derived organisms and the development of a fistula (odds ratio 0.48 (95% confidence interval 0.17 to 1.37)) or recurrence of perianal abscess (odds ratio 1.66 (0.46 to 6.01)). 19 Furthermore, a multicentre, double-blinded randomised trial showed that antibiotic treatment after abscess drainage offered no protection against subsequent fistula formation.…”

Section: Abscess or Fistula?mentioning

confidence: 99%

Perianal abscess

Sahnan

Adegbola

Tozer

et al. 2017

BMJ

View full text Add to dashboard Cite

Bacteriological study in perianal abscess is not useful and not cost‐effective

Abstract: Bacteriological culture in perianal abscess is not useful for predicting the development of anal fistula or abscess recurrence. Hence, there is no need to perform this investigation on a routine basis.

Cited by 23 publications

References 11 publications

Perianal Infections in the Phase before Engraftment after Allogeneic Hematopoietic Stem Cell Transplantations: A Study of the Incidence, Risk Factors, and Clinical Outcomes

Perianal Infections in the Phase before Engraftment after Allogeneic Hematopoietic Stem Cell Transplantations: A Study of the Incidence, Risk Factors, and Clinical Outcomes

Treatment of Perianal Abscess and Fistula in Infants and Young Children: From Basic Etiology to Clinical Features

Perianal abscess

Contact Info

Product

Resources

About