Bacteriology of Adenoids in Children with Adenoid Hypertrophy despite Mometasone Furoate Administration

Külekçi, Mehmet; Torun, Muzeyyen Mama; Ipek, Havva Duru; Özdemir, Sinem; Can, Günay; Develioğlu, Ömer Necati; Tokman, Hrisi Bahar

doi:10.21767/2573-0282.100030

Cited by 2 publications

(3 citation statements)

References 20 publications

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“…20 There were two patients (11.76%) who had no changes in the adenoid size, however there was improvement in the symptoms. Similar results were reported by Kulekci et al 16 that 25% of patients studied have no experience adenoid reduction from nasoendoscopy evaluation after using mometasone furoate for 8 weeks, but symptoms or complaints were decreased. Both patients in our study were male and aged over 12 years old.…”

Section: Discussionsupporting

confidence: 89%

“…It is suspected that intranasal corticosteroid caused direct lympholytic effects, reduced adenoid and nasopharyngeal inflammation from its anti-inflammatory effects and decreased the role of adenoids as reservoirs of infection. 14,16 The anti-inflammatory effect of corticosteroids is mediated by glucocorticoid receptors (GR). GRα are expressed in almost all tissues and cells, and their concentration is significantly higher than GRβ.…”

Section: Discussionmentioning

confidence: 99%

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Mometasone furoate effect on interleukin-6 of adenoid surface and serum in adenoid hypertrophy patients

Mujahid

Suheryanto

Maharani

2021

Oto Rhino Laryn Indones

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Background: Adenoid hypertrophy is one of the most common problems in children resulting in obstruction of the posterior nasal. Interleukin-6 (IL-6) is a pleiotropic cytokine that plays a role in acute and chronic infections, hematopoesis, T cells and B cells formation. Purpose: To determine the effect of intranasal mometasone furoate administration on IL-6 level of adenoid surface and serum and the adenoid size in patients with adenoid hypertrophy. Method: A one group pre- and posttest design involving 17 patients age 5 to 14 years. The patients underwent nasoendoscopic examination to determine the adenoid size, measurement of adenoid surface IL-6, and serum IL-6 level before and after 6 weeks treatment of intranasal mometasone furoate. Results: There were significant decrease of the adenoid surface IL-6 level, serum IL-6 level, and adenoid size with a p value <0.05. There was a significant positive correlation between the levels of adenoid surface IL-6 and serum IL-6 (r=0.517; p=0.033). A significant positive correlation was obtained between the decrease of adenoid surface and serum IL-6 levels with the decrease of adenoid size (p<0.05). Conclusion: The use of intranasal mometasone furoate can decrease the IL-6 levels of adenoid surface and serum, and the adenoid size in patients with adenoid hypertrophy.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Mometasone furoate effect on interleukin-6 of adenoid surface and serum in adenoid hypertrophy patients

Mujahid

Suheryanto

Maharani

2021

Oto Rhino Laryn Indones

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“…Sleep architecture in the common phenotype of pediatric OSAS is altered in aspects such as total sleep time, wake -up after sleep onset, sleep latency (minutes), excitation -spontaneous, respiratory and moving index, also interfering with the efficiency of the deep sleep [12].…”

Section: Anatomical Architecture Of Adenoid Hypothydria and Sleep Apneiamentioning

confidence: 99%

Relationship between adenoid hypertrophy and sleep apnea in children

Lira

Silva

2019

BDS

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It was decided to organize this work on the assumption that it is necessary for all dental surgeons to familiarize themselves with the structure and alterations in oral anatomy from childhood, with attention to the possibility of adenoid hypertrophy (AH) and obstructive sleep apnea syndrome (OSAS) to be present, and these professionals can assist in orthodontic treatment. The objective of this literature review was to observe if there is a correlation between adenotonsillar hypertrophy and sleep apnea in children and which treatment were adopted. The following databases were searched: LILACS, MEDLINE, PubMed, Cochrane, Web of Science and SciELO, from January 2014 to August 2018. It is concluded that there is a correlation between hypertrophy of the adenoid glands and apnea of the sleep in children. Hypertrophy presents as the main cause of obstructive sleep apnea syndrome in pediatric patients and its treatment may be surgical, removal of the adenoid, drug or orthodontic glands.

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Bacteriology of Adenoids in Children with Adenoid Hypertrophy despite Mometasone Furoate Administration

Cited by 2 publications

References 20 publications

Mometasone furoate effect on interleukin-6 of adenoid surface and serum in adenoid hypertrophy patients

Mometasone furoate effect on interleukin-6 of adenoid surface and serum in adenoid hypertrophy patients

Relationship between adenoid hypertrophy and sleep apnea in children

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