Bacteriuria in Pregnancy

Kincaid‐Smith, Priscilla; Bullen, Margaret

doi:10.1016/s0140-6736(65)90001-2

Cited by 235 publications

(79 citation statements)

References 22 publications

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“…4 Eleven studies were RCTs, and four were nonrandomized controlled clinical trials. All but one, in Jamaica, 20 were conducted in high-income countries, including the US, 6,[21][22][23][24] United Kingdom, [25][26][27] Ireland, 28 Australia, [29][30][31] Denmark 32 and the Netherlands. 4 Studies varied in terms of testing protocols (e.g., timing during pregnancy, number of confirmatory urine…”

Section: Treatmentmentioning

confidence: 99%

Recommendations on screening for asymptomatic bacteriuria in pregnancy

Moore

Doull

Grad

et al. 2018

CMAJ

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Section: Treatmentmentioning

confidence: 99%

Recommendations on screening for asymptomatic bacteriuria in pregnancy

Moore

Doull

Grad

et al. 2018

CMAJ

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“…At present, the only certain conclusion is that the risk of progression to pyelonephritis greatly increases during pregnancy, with rates as high as 30% reported among untreated women. [1][2][3][4][5][6][7] Antepartum urinary tract infection has also been implicated as a risk factor for adverse perinatal outcomes-premature birth and/or low birthweightl,3-5'7-14 and perinatal deathl"4'9-in numerous observational studies. However, an equal number of negative findings have been reported.2'6"15-28 Results tritis.…”

mentioning

confidence: 99%

Urinary tract infection during pregnancy: its association with maternal morbidity and perinatal outcome.

et al. 1994

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OBJECTIVES. The effects of antepartum urinary tract infection on adverse maternal and perinatal outcomes were examined. Antepartum urinary tract infection has been previously implicated as a risk factor for numerous outcomes. METHODS. Crude and multivariable analyses were performed with a perinatal registry cohort of 25,746 mother/infant pairs. RESULTS. Elevated risks were observed for exposure to urinary tract infection and low birthweight, prematurity, preterm low birthweight, premature labor, hypertension/preeclampsia, maternal anemia, and amnionitis. Urinary tract infection was associated with perinatal death only among subjects 20 to 29 years of age. CONCLUSIONS. These findings underscore the importance of antepartum urine screening to identify patients at risk for adverse outcomes.

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“…Interestingly, several authors reported a local response even in the absence of clinical symptoms. A local response includes mainly pyuria (Bachman et al, 1993, Hooton et al, 2000, Kincaid-Smith &Bullen, 1965, Kunin et al, 1964, Nicolle, 1997, Zhanel et al, 1995, although other local inflammatory or immune markers, including cytokines and urinary immunoglobulins, may also be present (Nicolle, 1997, Svanborg &Godaly, 1997.…”

Section: Causes and Pathogenesis Of Asymptomatic Bacteriuriamentioning

confidence: 99%