2023
DOI: 10.1038/s41401-023-01187-3
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Baicalein attenuates rotenone-induced SH-SY5Y cell apoptosis through binding to SUR1 and activating ATP-sensitive potassium channels

De-wen Kong,
Li-da Du,
Run-zhe Liu
et al.
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“…We employed SH-SY5Y cells treated with rotenone as an in vitro cellular model of Parkinson's disease to simulate neuronal injury by inducing ROS. 40,41 As depicted in Fig. S2,† rotenone treatment elevated ROS levels, thereby increasing the o 8 G content in both the SH-SY5Y cell line and the lower-grade glioma cell line HS683 (see Fig.…”
Section: Resultsmentioning
confidence: 99%
“…We employed SH-SY5Y cells treated with rotenone as an in vitro cellular model of Parkinson's disease to simulate neuronal injury by inducing ROS. 40,41 As depicted in Fig. S2,† rotenone treatment elevated ROS levels, thereby increasing the o 8 G content in both the SH-SY5Y cell line and the lower-grade glioma cell line HS683 (see Fig.…”
Section: Resultsmentioning
confidence: 99%