Baicalin ameliorates Mycoplasma gallisepticum-induced inflammatory injury via inhibiting STIM1-regulated ceramide accumulation in DF-1 cells

Chen, Xueping; Ishfaq, Muhammad; Wang, Jian

doi:10.1016/j.psj.2023.102687

Cited by 1 publication

(1 citation statement)

References 34 publications

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“…At the same time, it is noted that the proper dosage of glycyrrhizic acid treatment (100 mg/kg per day) has no significant adverse effects on broiler chickens (Hu et al, 2022). Baicalin, an active compound found in Scutellaria baicalensis, shows therapeutic potential for chickens infected with MG. Baicalin can alleviate pulmonary pathological changes caused by MG infection, reduce oxidative stress and cell apoptosis, and protect the thymus from structural and functional damage induced by MG infection (Li et al, 2019;Zou et al, 2021;Bao et al, 2021;Chen et al, 2023).…”

Section: Drug Prevention and Treatment Planmentioning

confidence: 99%

Mycoplasma galliscepticum: An overview

Ruizhi,

Xi,

Huiqi

et al. 2024

Afr. J. Microbiol. Res.

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The prokaryotic microorganism Mycoplasma gallisepticum (MG) belongs to the phylum Firmicutes, the order Mycoplasmatales, the family Mycoplasmataceae, and the genus Mycoplasma. MG parasitizes the respiratory tract of various poultry species, causing a range of symptoms from indistinct features to tracheitis and air sacculitis. Common signs include respiratory tract infection indicators such as coughing, asthma, a runny nose and rales. Both domestic and international reports underscore MG's transmission and infection capacity, signifying its global importance as a source of poultry infection. Further research is imperative to grasp its impact on both farmed and wild animals. This article comprehensively reviews current research progress on MG, encompassing its biological characteristics, infection traits, pathogenic mechanisms, epidemiology, detection methods, treatment, and control measures. It aims to serve as a reference for comprehensive prevention and control strategies against MG in the future.

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