Bakteri dan Multiresisten Obat (Multi Drugresistance) pada Pasien dengan Kateter Urin di RSUD Petala Bumi Pekanbaru

Endriani, Rita; Anggraini, Dewi; Rachmaliza, Rachmaliza; Wandari, Rika

doi:10.26891/jik.v10i2.2016.121-131

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…Subsequently, from 2010 to 2012, it increased to 26.4% (Dirar et al, 2020). According to research conducted at Sanglah Hospital in Denpasar Bali that the CTX-M gene was detected in 77.3% of 97 Klebsiella pneumoniae samples (Endriani et al, 2016). This study aims to detect the CTX-M gene, which is the most common ESBL-encoding gene associated with antibiotic resistance.…”

Section: Introductionmentioning

confidence: 97%

Identification of the CTX-M Gene in Klebsiella Pneumoniae Producing Esbls in Uti Patients at a Private Hospital in Purwokerto, Banyumas Regency, Central Java - Cross Sectional Study

Kurniawan,

Setyono,

Utami Anjarawati

2023

J Vocat Heal Stud

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Background: The CTX-M gene in ESBLs-producing Klebsiella pneumoniae is associated with virulence factors and encodes for antibiotic resistance. There are currently 128 different varieties of CTX-M, which gene can hydrolyze beta-lactam medicines like cefotaxime. Purpose: Identify the CTX-M gene in Klebsiella pneumoniae from patients with Urinary Tract Infections (UTI) at a private hospital in Banyumas Region of Central Java, Indonesia. Method: Cross-sectional survey method was employed in this study. The subjects of the study comprised 40 patients with UTI admitted to a private hospital in Banyumas Region, Central Java, Indonesia. Using a direct molecular approach called Polymerase Chain Reaction (PCR) directed against the CTX-M gene, DNA was isolated from isolates cultured in CHROMagarTM ESBLs obtained from catheter urine samples. Result: A total of 4 out of 40 urine samples (10%) tested positive for ESBL-producing Klebsiella pneumoniae. The PCR was performed to detect the CTX-M gene in 100% of the strains. Conclusion: These findings suggest the presence of CTX-M gene found in ESBLs-producing Klebsiella pneumoniae in individuals with urinary tract infections in a private hospital in Purwokerto, Banyumas regency, Central Java, Indonesia. This information can be used to assess antibiotic administration practices.

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Section: Introductionmentioning

confidence: 97%

Identification of the CTX-M Gene in Klebsiella Pneumoniae Producing Esbls in Uti Patients at a Private Hospital in Purwokerto, Banyumas Regency, Central Java - Cross Sectional Study

Kurniawan,

Setyono,

Utami Anjarawati

2023

J Vocat Heal Stud

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Susceptibility Pattern of ESBL Urine Specimens in Non-Intensive Care Room at Ulin General Hospital

Wulandhany

Pratiwi

Muthmainah

et al. 2021

Indonesian J. Clin. Pathol. Med. Lab.

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Beta-lactam antibiotic resistance can occur in ESBL-producing bacteria such as E.coli and K.pneumoniae, which can cause UTI. One of the risk factors for infection is the non-intensive care space density level. The objective of this study was to determine the sensitivity pattern of ESBL-producing bacteria in urine specimens of patients in the non-intensive care of Ulin General Hospital, Banjarmasin, in the period of 2016-2018. A descriptive study with a cross-sectional design using data results of urine culture and antibiotic susceptibility patterns data in non-intensive care patients at Ulin General Hospital from 2016 to 2018. The urine test results showed 96 positive isolates of ESBL-producing bacteria, consisting of ESBL-E.coli (69.8%) and ESBL-K.pneumonia (30.2%). Antibiotics with low sensitivity tests were Penicillin, Cephalosporin, Monobactam, and Penicillin/beta-lactam inhibitor combinations. Contrastingly, antibiotics with high sensitivity were Aminoglycoside, Carbapenem, and Glycylcycline. It was concluded from this study that the ESBL-producing bacteria in urine specimens for non-intensive care patients of Banjarmasin Ulin General Hospital in the period of 2016-2018 showed varying sensitivity to antibiotics

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Bakteri dan Multiresisten Obat (Multi Drugresistance) pada Pasien dengan Kateter Urin di RSUD Petala Bumi Pekanbaru

Cited by 2 publications

References 4 publications

Identification of the CTX-M Gene in Klebsiella Pneumoniae Producing Esbls in Uti Patients at a Private Hospital in Purwokerto, Banyumas Regency, Central Java - Cross Sectional Study

Identification of the CTX-M Gene in Klebsiella Pneumoniae Producing Esbls in Uti Patients at a Private Hospital in Purwokerto, Banyumas Regency, Central Java - Cross Sectional Study

Susceptibility Pattern of ESBL Urine Specimens in Non-Intensive Care Room at Ulin General Hospital

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