With the growing trend of arable land abandonment, the potential threat to the security of the food supply has sparked public concern. In order to examine the impact of non-agricultural employment on food security, this study builds linear regression models for research based on panel data from counties in China’s old revolutionary base areas. The empirical results show that, although the impact of non-agricultural employment on total grain production is not significant, it has a significant negative impact on both area and productivity, which indicates that non-agricultural employment poses a challenge to food security. In addition, the study examines the potential benefits of non-farm employment on two aspects of food security, including intensive management and the increase of new business entities. Non-farm employment can also significantly promote intensive management, thereby reducing the food-security challenges brought by non-farm employment, while the benefits of new management entities are insignificant. These findings contribute to the optimization of economic policies related to agricultural development, including exploring land property rights reform systems to promote land transfer, strengthening labor quality improvement in the agricultural sector, and formulating supporting policies to stabilize non-agricultural employment in accordance with local conditions.