Balancing Risk and Uncertain Benefit in Pharmacotherapy for Pain in Kidney Transplant Recipients

Schrauben, Sarah J.; Becker, William C.

doi:10.2215/cjn.0000000000000031

CJASN

2023

DOI: 10.2215/cjn.0000000000000031

|View full text |Cite

Balancing Risk and Uncertain Benefit in Pharmacotherapy for Pain in Kidney Transplant Recipients

Sarah J. Schrauben

William C. Becker

Abstract: Chronic pain has a staggering prevalence of 11% among US adults and cost an estimated US$635 billion in 2016. 1 Due to higher prevalence of osteoarthritis, diabetes, obesity, and sedentary lifestyle, chronic pain is even more common among patients with kidney failure. 2 In the effort to manage chronic

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Book1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Medical Statistics in Drug Development and Regulatory Approval

Yingngam

2024

Advances in Bioinformatics and Biomedical Engineering

View full text Add to dashboard Cite

In the rapidly evolving field of pharmaceuticals, the application of medical statistics has become increasingly important. This chapter provides an insightful overview of the integral role that statistical analysis plays in the journey of drug development, highlighting its impact from preclinical trials to phase III studies as well as its significance in regulatory decision-making. This chapter begins by establishing the foundational principles of statistical methods in clinical research. Specific statistical models and techniques used to ensure the safety and efficacy of new drugs have been explored. Key topics include experimental design, hypothesis testing, data interpretation, and the management of potential biases. This chapter highlights the indispensability of robust statistical practices for achieving reliable and scientifically sound results, which are critical for gaining regulatory approval. In the future, this chapter discusses emerging trends in biostatistics and their potential impact on future drug development and approval processes.

show abstract

Medical Statistics in Drug Development and Regulatory Approval

Yingngam

2024

Advances in Bioinformatics and Biomedical Engineering

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Balancing Risk and Uncertain Benefit in Pharmacotherapy for Pain in Kidney Transplant Recipients

Cited by 1 publication

References 11 publications

Medical Statistics in Drug Development and Regulatory Approval

Medical Statistics in Drug Development and Regulatory Approval

Contact Info

Product

Resources

About