Balneotherapy for Fibromyalgia Syndrome: A Systematic Review and Meta-Analysis

Cao, Chun-Feng; Ma, Kunlong; Li, Qian-Lu; Luan, Fu-Jun; Wang, Qunbo; Zhang, Minghua; Viswanath, Omar; Myrcik, Dariusz; Varrassi, Giustino; Wang, Hai-Qiang

doi:10.3390/jcm10071493

Cited by 13 publications

(6 citation statements)

References 48 publications

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“…This finding was analogous to that of the previous study, 96 which reported a significant reduction in disease impact in older fibromyalgia patients after repetitive transcranial magnetic stimulation intervention. Likewise, Cao et al 97 found that balneotherapy significantly improved functional outcomes when compared with the controls. Evidence from preclinical studies suggests that transcranial magnetic stimulation, can alter synaptic plasticity, modify neural circuits and brain networks, and activate neurotransmitters.…”

Section: Discussionmentioning

confidence: 94%

Efficacy of electrophysical agents in fibromyalgia: A systematic review and network meta-analysis

et al. 2023

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Objective To examine the effectiveness of electrophysical agents in fibromyalgia. Data sources CINAHL, Cochrane Library, Embase, Medline, PEDro, and Web of Science were searched from their inceptions to March 27, 2023. Methods This study was registered in PROSPERO (CRD42022354326). Methodological quality of included trials was assessed using PEDro scale, and the quality of evidence was determined according to the Grading of Recommendations Assessment, Development, and Evaluation system. The primary outcomes were pain, functional status, and mood. Results Fifty-four studies involving 3045 patients with fibromyalgia were eligible for qualitative synthesis and 47 (pain), 31 (functional status), and 26 (mood) for network meta-analysis. The network consistency model revealed that, when compared with true control, transcutaneous electrical nerve stimulation and microcurrent improved pain symptoms ( P = 0.006 and P = 0.037, respectively); repetitive transcranial magnetic stimulation improved patient functional status ( P = 0.018); and microcurrent ( P = 0.001), repetitive transcranial magnetic stimulation ( P = 0.022), and no treatment ( P = 0.038) significantly improved mood after intervention. Surface under the cumulative ranking indicated that microcurrent was most likely to be the best for managing pain and mood (surface under the cumulative ranking: 70% and 100%, respectively); low-level laser therapy for pain and mood (80% and 70%, respectively); and repetitive transcranial magnetic stimulation for improving functional status and mood (80% and 70%, respectively). Conclusion This review found low to moderate quality evidence that microcurrent, laser therapy, and repetitive transcranial magnetic stimulation are the most effective electrophysical agents for improving at least one outcome in fibromyalgia.

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Section: Discussionmentioning

confidence: 94%

Efficacy of electrophysical agents in fibromyalgia: A systematic review and network meta-analysis

et al. 2023

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“…FMS is a chronic disease characterized by widespread muscle pain that reduces functional capability and QoL. In addition to other therapies, such as pharmacotherapy [72], balneotherapy [73] or physical exercise [74,75], VRBT has emerged as a new therapy that can reduce the impact of FMS symptoms. The present study proposed to compile the scientific evidence published to date to analyze the effectiveness of VRBT on the impact of FMS and in other related outcomes.…”

Section: Discussionmentioning

confidence: 99%

Virtual Reality-Based Therapy Reduces the Disabling Impact of Fibromyalgia Syndrome in Women: Systematic Review with Meta-Analysis of Randomized Controlled Trials

Cortés‐Pérez

Zagalaz-Anula

Ibancos-Losada

et al. 2021

JPM

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Background: Virtual reality-based therapy (VRBT) is a novel therapeutic approach to be used in women with fibromyalgia syndrome (FMS). The aim of our study is to assess the effect of VRBT to reduce the impact of FMS in outcomes such as pain, dynamic balance, aerobic capacity, fatigue, quality of life (QoL), anxiety and depression. Methods: Systematic review with meta-analysis was conducted from a bibliographic search in PubMed, Scopus, PEDro, Web of Science and CINAHL until April 2021 in accordance with PRISMA guidelines. We included randomized controlled trials (RCTs) that compare VRBT versus others to assess the mentioned outcomes in women with FMS. Effect size was calculated with standardized mean difference (SMD) and its 95% confidence interval (95% CI). Results: Eleven RCTs involving 535 women with FMS were included. Using the PEDro scale, the mean methodological quality of the included studies was moderate (6.63 ± 0.51). Our findings showed an effect of VRBT on the impact of FMS (SMD −0.62, 95% CI −0.93 to −0.31); pain (SMD −0.45, 95% CI −0.69 to −0.21); dynamic balance (SMD −0.76, 95% CI −1.12 to −0.39); aerobic capacity (SMD 0.32, 95% CI 0.004 to 0.63); fatigue (SMD −0.58, 95% CI −1.02 to −0.14); QoL (SMD 0.55, 95% CI 0.3 to 0.81); anxiety (SMD −0.47, 95% CI −0.91 to −0.03) and depression (SMD −0.46, 95% CI −0.76 to −0.16). Conclusions: VRBT is an effective therapy that reduces the impact of FMS, pain, fatigue, anxiety and depression and increases dynamic balance, aerobic capacity and quality of life in women with FMS. In addition, VRBT in combination with CTBTE showed a large effect in reducing the impact of FMS and fatigue and increasing QoL in these women.

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“…Balneotherapy, a form of hydrotherapy that involves immersion in mineral-rich water, has been studied for its potential benefits in fibromyalgia patients [ 93 ]. Future research could further explore the effects of balneotherapy on fibromyalgia symptoms and identify the optimal treatment protocols.…”

Section: Reviewmentioning

confidence: 99%

Beyond the Pain: A Systematic Narrative Review of the Latest Advancements in Fibromyalgia Treatment

Ram,

Jeyaraman,

Jeyaraman

et al. 2023

Cureus

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Fibromyalgia is a complex chronic pain disorder that significantly impacts the quality of life of affected individuals. The etiology of fibromyalgia remains elusive, necessitating effective treatment options. This review aims to provide an overview of current treatment options for fibromyalgia and highlight recent updates in managing the condition. The methodology employed in this systematic review comprised the following key steps. We conducted a comprehensive search across various databases to identify pertinent studies published between 2000 and 2023. Inclusion criteria were defined to specifically target studies involving adult individuals diagnosed with fibromyalgia, with a focus on both pharmacological and non-pharmacological interventions for managing the condition. The review encompassed a range of study types, including randomized controlled trials, observational studies, and systematic reviews. To ensure the quality of the selected studies, we employed appropriate assessment tools, and data extraction and synthesis adhered to established guidelines. This rigorous approach allowed for a robust analysis of the literature on fibromyalgia management. In the course of our review, it became evident that a spectrum of treatment approaches holds significant promise in the management of fibromyalgia. Specifically, pharmacological interventions, including selective serotonin-norepinephrine reuptake inhibitors, anticonvulsants, cannabinoids, tropisetron, and sodium oxybate, have exhibited substantial potential in alleviating fibromyalgia symptoms. Concurrently, non-pharmacological strategies, such as cognitive-behavioral therapy, exercise regimens, and complementary and alternative therapies, have yielded positive outcomes in improving the condition's management. Recent developments in the field have introduced innovative pharmacological agents like milnacipran and pregabalin, in addition to non-pharmacological interventions like mindfulness-based stress reduction and aquatic exercise, expanding the array of options available to enhance fibromyalgia care and alleviating patient symptoms. Fibromyalgia necessitates a multidisciplinary approach to treatment, encompassing both pharmacological and non-pharmacological interventions. Recent updates in fibromyalgia management offer additional options to alleviate symptoms and improve the quality of life for individuals with fibromyalgia. Healthcare professionals should remain informed about these advancements to provide evidence-based care, addressing the complex symptoms associated with fibromyalgia and enhancing patient outcomes.

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Balneotherapy for Fibromyalgia Syndrome: A Systematic Review and Meta-Analysis

Cited by 13 publications

References 48 publications

Efficacy of electrophysical agents in fibromyalgia: A systematic review and network meta-analysis

Efficacy of electrophysical agents in fibromyalgia: A systematic review and network meta-analysis

Virtual Reality-Based Therapy Reduces the Disabling Impact of Fibromyalgia Syndrome in Women: Systematic Review with Meta-Analysis of Randomized Controlled Trials

Beyond the Pain: A Systematic Narrative Review of the Latest Advancements in Fibromyalgia Treatment

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