Bananas and Biotech Consumers

Hassler, Susan

doi:10.1038/nbt0595-417

Cited by 5 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dental caries is caused by this bacterium, it was predicted that the stimulation of a mucosal immune response could prevent the bacteria from colonizing the tooth and therefore defend in opposition to tooth decay. promoter could be an important tool [8]. There are some drawbacks of banana using as an edible vaccine that it quickly spoils after ripening and the amount of protein contain very smaller.…”

Section: Early Progresses Of the Edible Vaccine Developmentmentioning

confidence: 99%

A review on natural way of vaccination: Plant derived edible vaccines

Khan¹,

Khan²,

Shehzad³

et al. 2019

J Vaccines Immunol

View full text Add to dashboard Cite

Immunizing human or animals with edible plants is an evolving tool that seems to grip countless potential. The selected/desired antigen of pathogens (HIV, tuberculosis etc) are inserted to the selected host plant by transformation technique to form a transgenic plant. Edible vaccines grip countless promise as a profi table, easily managing, can be store easily, unlikely or unable to fail and sociocultural gladly sustainable, particularly for the poor emerging nations. An edible vaccine takes the place of sore immunization methods. Compare to conventional vaccine, edible vaccine is inexpensive, needle free, eradicates the requirement for preservation, harmless, may be stored nearby to place of usage, and deliver mucosal and complete immunity. For the enhancing immunity in human and animal against Various type of infectious diseases such as cholera, measles, FMD and hepatitis B there are numerous types of edible vaccines are being developed. Edible vaccines also help to overpower auto immunity diseases alike type-I diabetes. Immunization generations and giving malnutrition have the dual advantages of edible vaccine. If the notable problem and challenges may be triumph over It also can bring about a destiny of more secure and further effective immunization.

show abstract

Section: Early Progresses Of the Edible Vaccine Developmentmentioning

confidence: 99%

A review on natural way of vaccination: Plant derived edible vaccines

Khan¹,

Khan²,

Shehzad³

et al. 2019

J Vaccines Immunol

View full text Add to dashboard Cite

show abstract

“…Banana (Hassler 1995) is a good candidate for plant-based vaccines since they are eaten raw, appealing to children, inexpensive to produce, native to many developing countries. Even though banana can be easily transformed (May et al 1995) due to the low protein content of the fruit, the amount of antigen expressed will be limited and takes long time for transformation to evaluation of fruit.…”

Section: Introductionmentioning

confidence: 99%

Transgenic Cucumis sativus Expressing the Hepatitis B Surface Antigen

Unni

Soniya

2010

Plant Mol Biol Rep

View full text Add to dashboard Cite

A DNA fragment encoding the hepatitis B virus surface antigen was amplified from a positive blood (hepatitis B) sample and introduced into the pET 32c prokaryotic expression vector. The gene encoding the HBV surface protein antigen was introduced into pCAMBIA 3300, and immobilized into Agrobacterium tumefaciens strain LBA4404. Cotyledonary leaf sections of Cucumis sativus (cucumber) cv 'Swarnamukhi' were cocultivated with Agrobacterium harboring the binary vector pCAMBIA 3300 carrying the HBV surface antigen gene driven by the CaMV35S promoter and the herbicide resistance gene phosphinothricin. Putative transformed shoots were induced on a Murashige and Skoog (MS) medium containing phosphinothricin, and these were then rooted on MS basal medium supplemented with 1 mg/L Indole 3-butyric acid (IBA). Integration of the T-DNA into in putative transgenic plants was confirmed by PCR and Southern blot analyses. RT-PCR and Northern blot analyses were conducted to determine RNA expression. Levels of expression in transgenic plants were confirmed by Western blot analysis, and quantification of the protein was determined by enzyme linked immuno assay (ELISA). Molecular mass of the recombinant protein was measured by Matrix-Assisted Laser Desorption Ionization-Time-of-Flight (MALDI-TOF) Mass Spectrometry.

show abstract

“…Potatoes are a good system in which to test the idea of edible vaccines (Steinberg, 1996). Bananas (Hassler, 1995) is a good candidate for edible vaccines since they were eaten raw, appealing to children, inexpensive to produce, native to many developing countries. But the only limitation is the time from transformation to evaluation of fruit is 2 years or more.…”

Section: Introductionmentioning

confidence: 99%

Green revolution vaccines, edible vaccines

Tripurani¹,

Reddy²,

Rao³

2003

Afr. J. Biotechnol.

View full text Add to dashboard Cite

Edible vaccines are sub-unit vaccines where the selected genes are introduced into the plants and the transgenic plant is then induced to manufacture the encoded protein. Edible vaccines are mucosal targeted vaccines where stimulation of both systematic and mucosal immune network takes place. Foods under study include potatoes, bananas, lettuce, rice, wheat, soybean, corn and legumes. Edible vaccines for various diseases such as measles, cholera, hepatitis-B, and many more are in the process of development. Food vaccines may also help to suppress autoimmunity disorders such as Type-1 Diabetes.

show abstract

Bananas and Biotech Consumers

Cited by 5 publications

References 0 publications

A review on natural way of vaccination: Plant derived edible vaccines

A review on natural way of vaccination: Plant derived edible vaccines

Transgenic Cucumis sativus Expressing the Hepatitis B Surface Antigen

Green revolution vaccines, edible vaccines

Contact Info

Product

Resources

About