“…The most common approach is for all functional components to reside on rigid device “islands” that are electrically and mechanically linked by stretchable/deformable interconnects (Choi et al, 2016; Lu and Yang, 2015; Ma et al, 2017; Song, 2015; Zhang et al, 2015). These interconnects can either adopt an out-of-plane arc shape formed by buckling due to release of substrate pre-strain (Jones et al, 2004; Khang et al, 2006; Lacour et al, 2005; Ma et al, 2016b; Su et al, 2012; Wang et al, 2017), or an in-plane serpentine shape (Gonzalez et al, 2008; Huyghe et al, 2008; Liu and Lu, 2016; Xu et al, 2017; Zhang and Parnell, 2017), to achieve stretchability at the system level. Such systems with islands and interconnects are always integrated on or encapsulated into solid substrates that support and protect the systems when mounted on biological tissues (Li et al, 2017a).…”