Banque des sérums antivenimeux : actualités et veille nationale sur les envenimations par serpents exotiques

Boels, D.; Gégu, Clément; Haro, Luc de; Sapori, Jean-Marc; Chippaux, Jean‐Philippe; Quistinic, Pierre; Clerc, M.; Penot-Ragon, Christine; Leboucher, Gilles; Harry, P.

doi:10.1016/j.toxac.2014.09.009

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In order to assist clinicians in the management of bites by venomous species, French breeding centers and PCCs joined forces in 2003 in an association called the 'Banque des sérums antivenimeux (BSA)' [39,40]; the aim of the association is to purchase foreign antivenomous serum that meets French standards of safety and efficacy. The financing of the doses is ensured by the contributions of the breeders themselves.…”

Section: Discussionmentioning

confidence: 99%

Bites by Non-Native Reptiles in France: Species, Circumstances and Outcome

Roux

Grenet

Schmitt³

et al. 2022

Toxins

View full text Add to dashboard Cite

We aimed to make an exhaustive assessment of circumstances of bites by exotic reptiles bred in France. A retrospective observational study was conducted in all the reported cases from 2000 to 2020 in French poison control centers (PCCs). Two hundred and eighteen cases of bites were recorded. The sex ratio (M/F) of the patients was 1.79 and the mean age of the patients was 29.0 ± 15.8 years. Twenty-two cases (10.1%) occurred during the deep night. One hundred and eighty-six bites (85.7%) occurred in a private context; however, there were more cases of high severity when it occurred in a professional setting (60.0% vs. 11.2%, p < 0.01). The feeding/nursing activity accounted for 54.7% cases. Forty-three species of snake were identified; 28 were considered venomous. There were no deaths among the patients in the study. Most of the cases (85.8%) were of mild severity. All of the patients bitten by a venomous reptile were hospitalized: 10 patients received an antivenom; and 2 required surgery. Bites occurred at home and by a small number of popular non-venomous reptile species (pythons and boas, colubrids). These occurred mainly when handling the animals. The rare envenomations were mainly by Asian and American crotalids, followed by elapids. One-third of them were treated with antivenom when available.

show abstract

Section: Discussionmentioning

confidence: 99%

Bites by Non-Native Reptiles in France: Species, Circumstances and Outcome

Roux

Grenet

Schmitt³

et al. 2022

Toxins

View full text Add to dashboard Cite

show abstract

“…In 2017, the French Health Authority decided the use of AV in FG. The AV chosen was the Antivipmyn Tri, deemed effective against most of the snakes encountered in the region [ 4 ]. However, the efficacy of this AV remains controversial [ 2 , 5 , 6 ], and one of the causes of poor efficacy in some cases might be a delayed AV administration.…”

Section: Introductionmentioning

confidence: 99%

Effect of the time to antivenom administration on recovery from snakebite envenoming-related coagulopathy in French Guiana

et al. 2023

View full text Add to dashboard Cite

Background Snakebite (SB) envenoming is an acute emergency requiring an early care delivery. We aimed to search for the time to reach healthcare facilities in various regions of French Guiana (FG) and to assess the impact of time to antivenom (AV) on the correction of coagulation parameters in these patients. Methodology This is a prospective observational study conducted in Cayenne General Hospital between January 1st, 2016, and July 31st, 2022. We included all patients hospitalized for SB envenoming less than 48h after the bite, and receiving antivenom (AV). We assessed the time lapse between SB and medical attention and the time needed to return of the coagulation parameters to normal. Principal findings Overall, 119 patients were investigated, and 48.7% were from remote areas. The median time from SB to AV therapy was 09:15 h (05:32–17:47). The time was longer in patients from remote rural locations. AV was dispensed within the first six hours after the SB in 45 cases (37.8%). Time from SB to reaching normal plasma fibrinogen concentration was 23:27 h (20:00–27:10) in patients receiving AV≤6h vs. 31:23 h (24:00–45:05) in those receiving AV>6h (p<0.001). Whereas, the time from AV administration to reach normal fibrinogen dosage was similar in the two groups. Conclusions Patients from rural settings in FG suffer from a delay in AV administration after SB envenoming leading to an extended time in which patients are coagulopathic. Once AV is administered, clotting parameters recover at a similar rate. Supplying remote healthcare facilities with AV and with medical teams trained in its use should be planned.

show abstract

Banque des sérums antivenimeux : actualités et veille nationale sur les envenimations par serpents exotiques

Cited by 2 publications

References 0 publications

Bites by Non-Native Reptiles in France: Species, Circumstances and Outcome

Bites by Non-Native Reptiles in France: Species, Circumstances and Outcome

Effect of the time to antivenom administration on recovery from snakebite envenoming-related coagulopathy in French Guiana

Contact Info

Product

Resources

About