Bare-metal stenting of large coronary arteries in ST-elevation myocardial infarction is associated with low rates of target vessel revascularization

Shugman, I.; Hee, L.; Mussap, C.; Diu, Patrick; Lo, S.; Hopkins, A.; Nguyen, Phong; Taylor, David; Rajaratnam, R.; Leung, Dominic Y.; Thomas, Liza; Juergens, C.; French, John K.

doi:10.1016/j.ahj.2012.12.023

Cited by 14 publications

(11 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…10 Stent deployment was performed according to our institutions' DES selective use criteria, 11–12 and angiographic successful procedures were defined as final post‐PCI minimum stenosis diameter reduction to <20% in cases after stenting or to <50% after balloon angioplasty in the presence of grade 3 Thrombolysis In Myocardial Infarction (TIMI) flow. 13 …”

Section: Methodsmentioning

confidence: 99%

“…14 The composite of major adverse cardiac events (MACEs) include death/MI/TVR/ST, as previously reported. 11 In brief, trained research staff (nurses or doctors) contacted patients, their relatives, or local physicians by phone and were asked about recurrent cardiac symptoms requiring hospitalization, particularly coronary revascularization, or MI. Data regarding death were obtained from family members, physicians, medical records, and death registry.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Varying Definitions for Periprocedural Myocardial Infarction Alter Event Rates and Prognostic Implications

Idris

Shugman

et al. 2014

JAHA

Self Cite

View full text Add to dashboard Cite

BackgroundPeriprocedural myocardial infarction (PMI) has had several definitions in the last decade, including the Society for Cardiovascular Angiography and Interventions (SCAI) definition, that requires marked biomarker elevations congruent with surgical PMI criteria.Methods and ResultsThe aim of this study was to examine the definition‐based frequencies of PMI and whether they influenced the reported association between PMI and increased rates of late death/ myocardial infarction (MI). We studied 742 patients; 492 (66%) had normal troponin T (TnT) levels and 250 (34%) had elevated, but stable or falling, TnT levels. PMI, using the 2007 and the 2012 universal definition, occurred in 172 (23.2%) and in 99 (13.3%) patients, respectively, whereas 19 (2.6%) met the SCAI PMI definition (P<0.0001). Among patients with PMI using the 2012 definition, occlusion of a side branch ≤1 mm occurred in 48 patients (48.5%) and was the most common angiographic finding for PMI. The rates of death/MI at 2 years in patients with, compared to those without, PMI was 14.7% versus 10.1% (P=0.087) based on the 2007 definition, 16.9% versus 10.3% (P=0.059) based on the 2012 definition, and 29.4% versus 10.7% (P=0.015) based on the SCAI definition.ConclusionIn this study, PMI, according to the SCAI definition, was associated with more‐frequent late death/MI, with ≈20% of all patients, who had PMI using the 2007 universal MI definition, not having SCAI‐defined PMI. Categorizing these latter patients as SCAI‐defined no PMI did not alter the rate of death/MI among no‐PMI patients.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Varying Definitions for Periprocedural Myocardial Infarction Alter Event Rates and Prognostic Implications

Idris

Shugman

et al. 2014

JAHA

Self Cite

View full text Add to dashboard Cite

show abstract

“…Procedure-related factors such as minimal stent crosssectional area, stent length, and multiple stenting have been reported as predictors of stent restenosis in many studies [13,15,16] although these factors are influenced by the known lesion-specific predictors of restenosis; vessel diameter <3.5 mm and lesion length [13,14]. In our study, stent size was relevant to restenosis but not to early SO.…”

Section: Discussionmentioning

confidence: 53%

“…Some studies have reported patient-related clinical factors such as hypertension and diabetes mellitus as predictors of stent restenosis [13,14]. Procedure-related factors such as minimal stent crosssectional area, stent length, and multiple stenting have been reported as predictors of stent restenosis in many studies [13,15,16] although these factors are influenced by the known lesion-specific predictors of restenosis; vessel diameter <3.5 mm and lesion length [13,14].…”

Section: Discussionmentioning

confidence: 99%

Incidence and Clinical Predictors of Stent Restenosis and Early Stent Occlusion in Patients with Acute Myocardial Infarction Treated by Bare Metal Stents: Importance of Infarct Location and Serum Creatinine Level

Uemori¹,

Sugitani²,

Tamada³

et al. 2014

Angiol

View full text Add to dashboard Cite

GroupsAmong these 242 patients, 226 underwent either ischemia-driven or planned follow-up coronary angiography within 8 months. Thus, *Corresponding author: Manabu Shirotani, Cardiology Department, Nara Hospital, Kinki University Faculty of Medicine, 1248-1, Otoda-Cho, Ikoma, Nara, 630-0293, Japan, Tel: +81 743 77 0880; Fax: +81 743 77 0901; E-mail: manabu@nara.med.kindai.ac.jp AbstractBackground: Bare Metal Stents (BMS) have been commonly used for recanalization of an infarct-related artery in Japanese patients with Acute Myocardial Infarction (AMI). We sought to examine predictors of binary restenosis and early Stent Occlusion (SO) in these patients. Methods:Among 242 consecutive patients with AMI treated by BMS implantation as reperfusion therapy, 226 underwent either ischemia-driven or follow-up coronary angiography within 8 months. Restenosis change in the stented segment was found in 56. Among them, 10 patients had early SO on an angiogram. Multivariate analysis was performed to obtain predictors of restenosis and early SO.Results: Predictors for restenosis were Left Anterior Descending Artery (LAD) involvement (odds ratio (OR) 2.32, p=0.024), serum creatinine (SCr) on admission (OR 1.29 per 0.1mg/dl increase, p=0.001), and stent size (OR 0.43 per 0.5mm increase, p=0.001). Those for early SO were left main trunk or LAD involvement (OR 27.0, p=0.029), SCr (OR 1.65 per 0.1mg/dl increase, p=0.005) and leukocyte count (OR 1.28 per 1,000/microliter increase, p=0.037) on admission. SCr was significantly higher in patients with early SO than in those with restenosis (median 1.05, Interquartile Range (IQR) 0.80-1.10 vs. median 0.80, IQR 0.70-1.00, p=0.035). Conclusion:In patients with AMI treated with BMS, both restenosis and early SO were increased by anterior wall involvement and elevation of SCr level. Higher SCr may be subject to more occlusive changes. It is suggested that in early SO, an inflammatory mechanism may be involved.

show abstract

“…The present mean balloon diameter of the stent (near 3.50 mm) and postprocedural reference diameter (≥ 3.10 mm) indicated that large vessels were treated in the present cohort because the frequency of TLR after a bare-metal stent (BMS) was relatively low in these baselines. [21][22][23][24] Considering this background, the present study showed far better angiographic outcomes for BES compared to SES, because SES showed a prominent advantage for angiographic outcomes in large vessels compared to the contemporary BMS 23) and zotarolimus-eluting stent, 24) and because angiographic efficacy was equal in large vessels between SES and EES in terms of target vessel failure. 23) Accordingly, the present study is the first to show the efficacy of BES on midterm angiographic outcomes compared to SES after being used in a clinical setting.…”

Section: Discussionmentioning

confidence: 97%

Propensity-Score Matched Comparison of Midterm Angiographic Outcomes of Sirolimus- Versus Everolimus- and Biolimus-Eluting Stents for <i>De Novo</i> Coronary Stenosis

et al. 2017

View full text Add to dashboard Cite

SummaryWe conducted propensity-score matched comparisons of midterm angiographic outcomes of sirolimus (SES) versus either everolimus-(EES) or biolimus-(BES) eluting stents after placements for coronary stenosis in a daily practice environment since previous randomized trials did not demonstrate the superiority of EES and BES over SES in terms of midterm angiographic outcomes.The present study was a non-randomized, retrospective, and lesion-based study, recruiting angiographically followed-up lesions within 550 days after successful and elective SES (n = 1793), EES (n = 1303), or BES (n = 324) placement for de novo native coronary stenosis during the period from August 2004 to January 2014 at 6 institutes. The endpoint, as an angiographic surrogate marker of clinical efficacy, was the distribution of in-stent follow-up percent diameter stenosis (%DS) which comprised the percentages of 1) follow-up %DS < 20 and 2) follow-up %DS > 50. Propensityscore matched analyses were conducted to adjust 21 baselines.In 1215 baseline adjusted lesions, the endpoints in the EES group [1) 74.1%, and 2) 4.6%] were significantly different from those in the SES group [57.9%; P < 0.001, 7.2%; P = 0.006, respectively). In 307 baseline adjusted lesions, the endpoints in the BES group [1) 80.5%, 2) 2.0%] were significantly different from those in the SES group [59.3%; P < 0.001, 2) 8.1%; P = 0.001, respectively].The present study is the first to confirm the superiority of midterm angiographic outcomes after the placement of EES and BES over SES for de novo coronary stenosis in a clinical setting. (Int Heart J 2017; 58: 320-327) Key words: Follow-up result, Angioplasty, Binary restenosis, Target lesion revascularization, Late luminal loss E verolimus-eluting stents (EES; Xience and Promus) have exhibited benefits associated with a favorable vascular response compared to sirolimus-eluting stents (SES; Cypher BxV and Select+), owing to their advanced drug-eluting stent (DES) technology that consists of the revised thin and flexible stent platform, anti-thrombogenic fluoropolymer, and drug. 1,2) The biolimus-eluting stent (BES; Nobori) also showed a better midterm intravascular response compared to SES, owing to its properties such as being a biodegradable polymer and the highest lipophilicity among the limus analogues. 3,4) However, despite these advanced aspects of EES and BES compared with the former evidence-based first generation "-limus" DES, that is, SES, prospective randomized trials have not demonstrated significantly better midterm angiographic outcomes for either EES 5,6) or BES 7,8) in terms of binary in-stent restenosis, TLR, or mean magnitude of in-stent late luminal loss compared to those of SES.In the present study, we conducted a retrospective comparison to examine the impact of the advances in coronary stent technology, represented by improved intravascular and pathological findings of either EES or BES over SES 1-4) on the overall midterm angiographic outcomes. For this purpose, 3420 lesions angiographically followed-up ...

show abstract

Bare-metal stenting of large coronary arteries in ST-elevation myocardial infarction is associated with low rates of target vessel revascularization

Cited by 14 publications

References 36 publications

Varying Definitions for Periprocedural Myocardial Infarction Alter Event Rates and Prognostic Implications

Varying Definitions for Periprocedural Myocardial Infarction Alter Event Rates and Prognostic Implications

Incidence and Clinical Predictors of Stent Restenosis and Early Stent Occlusion in Patients with Acute Myocardial Infarction Treated by Bare Metal Stents: Importance of Infarct Location and Serum Creatinine Level

Propensity-Score Matched Comparison of Midterm Angiographic Outcomes of Sirolimus- Versus Everolimus- and Biolimus-Eluting Stents for <i>De Novo</i> Coronary Stenosis

Contact Info

Product

Resources

About