Bariatric Surgery: Choosing the Optimal Procedure

Needleman, Bradley J.; Happel, Lynn

doi:10.1016/j.suc.2008.05.013

Cited by 19 publications

(11 citation statements)

References 43 publications

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“…De hecho, una carga de glucosa o lípidos en sujetos normales u obesos provoca un aumento en la generación de inflamación y disminución de la reactividad vascular 8 . Controversialmente, la restricción dietética en pacientes obesos provoca una reducción significativa en el estrés oxidativo y la inflamación 9 .…”

Section: Introductionunclassified

Nivel de proteína C reactiva en pacientes con obesidad mórbida antes y después de cirugía bariátrica

Rojano-Rodríguez

Valenzuela-Salazar

Cárdenas-Lailson

et al. 2014

Revista de Gastroenterología de México

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Section: Introductionunclassified

Nivel de proteína C reactiva en pacientes con obesidad mórbida antes y después de cirugía bariátrica

Rojano-Rodríguez

Valenzuela-Salazar

Cárdenas-Lailson

et al. 2014

Revista de Gastroenterología de México

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“…8 Controversially, dietary restriction in obese patients causes a significant reduction in oxidative stress and inflammation. 9 Van Dielen et al demonstrated a correlation between the levels of the inflammatory mediators, the acute phase proteins, and body weight. Even though a causal relation has not been found, it suggests that elevated levels of CRP are prognostic for the development of cardiovascular disease.…”

Section: Introductionmentioning

confidence: 99%

C-Reactive protein level in morbidly obese patients before and after bariatric surgery

Rojano-Rodríguez

Valenzuela-Salazar

Cárdenas-Lailson

et al. 2014

Revista de Gastroenterología de México (English Edition)

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Background: Human obesity is associated with a proinflammatory state and an elevated level of mediators, such as C-reactive protein (CRP). Objectives: To establish CRP levels as baseline preoperative values and then at 6 months after bariatric surgery, as well as to determine the changes in weight, body mass index (BMI), leukocytes, and glycemia. Materials and methods: An observational, analytical, retrospective, longitudinal, and open study was conducted. Serum CRP values were measured in 36 adults presenting with morbid obesity, and their baseline relation to weight, BMI, leukocytes, and glycemia was determined; the relation to the same parameters was established again, 6 months after bariatric surgery. Results: The mean and standard deviation of preoperative and postoperative CRP (mg/L) was 1.15 ± 0.86 and 0.34 ± 0.28, respectively with p < 0.0001; weight (kg) 112.10 ± 22.91 and 84.82 ± 17.11, p = 0.0443; BMI (kg/m 2 ) 42.48 ± 5.97 and 32.2 ± 4.79, p = 0.0988; glucose (mg/dL) 100.58 ± 17.82 and 87.11 ± 8.49, p < 0.0001, and leukocytes (× 10 3 /mm 3 ) 8.62 ± 1.69 and 6.99 ± 1.56, p = 0.3192.Baseline CRP only correlated with weight and BMI (p = 0.047 and p = 0.027 respectively) and there was no correlation between postoperative CRP and the evaluated parameters. Conclusions: Preoperative CRP had a significant lineal relation to weight and body mass index. Patients who underwent bariatric surgery had a significant decrease in CRP, weight, and fasting glucose at 6 months after surgery. Nivel de proteína C reactiva en pacientes con obesidad mórbida antes y después de cirugía bariátrica ResumenAntecedentes: La obesidad humana se asocia a un estado proinflamatorio reflejado en elevación de marcadores como la proteína C reactiva (PCR). Objetivos: Establecer los valores de PCR basales y a 6 meses de la cirugía bariátrica, así como los cambios en peso, índice de masa corporal (IMC), leucocitos y glucemia. Materiales y métodos: Se realizó un estudio observacional, analítico, retrospectivo, longitudinal y abierto. Se midieron los valores de PCR sérica y su relación con el peso, IMC, leucocitos y glucemia de manera basal y 6 meses posteriores a cirugía bariátrica en 36 adultos con obesidad mórbida. Resultados: La media ± desviación estándar de la PCR pre y posoperatorio (mg/l) fue 1.15 ± 0.86 y 0.34 ± 0.28, respectivamente, con p < 0.0001; peso (kg) 112.10 ± 22.91 y 84.82 ± 17.11, p = 0,0443; IMC (kg/m 2 ) 42.48 ± 5.97 y 32.2 ± 4.79, p = 0.0988; glucosa (mg/dl) 100.58 ± 17.82 y 87.11 ± 8.49, p < 0.0001, y leucocitos (× 10 3 /mm 3 ) 8.62 ± 1.69 y 6.99 ± 1.56, p = 0.3192.La PCR basal solo correlacionó con el peso e IMC (p = 0.047 y p = 0.027, respectivamente) y no hubo correlación entre la PCR posoperatoria y ninguno de los parámetros evaluados. Conclusiones: La PCR tiene una relación lineal significativa en el preoperatorio con el peso y el IMC. Los pacientes sometidos a cirugía bariátrica presentaron disminución significativa en la PCR, el peso y la glucemia en ayuno a los 6 meses posterior a la cirugía.

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“…RYGB has been reported by many to be the gold standard and most common surgical procedure for weight loss in the U.S . Outcome studies have shown the RYGB to result in excess weight loss of 55‐75% .…”

Section: Introductionmentioning

confidence: 99%

Musculoskeletal function following bariatric surgery

Iossi

Konstantakos

Teel

et al. 2013

Obesity

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Objective: Bariatric surgery is an effective method for acute weight loss. While the impact of bariatric surgery on general medical conditions (e.g., type 2 diabetes) is well documented, few studies focus on physical functional outcomes following weight-loss induced by bariatric surgery. Design and Methods: We report on 50 women aged 20-74 scheduled for Roux-en-Y gastric bypass (RYGB) procedure who were enrolled for a prospective 1-year study. Height, weight, and waist circumference were recorded preoperatively and at 6 and 12 months, postoperatively. To track musculoskeletal/physical function changes, the timed-get-up-and-go (TGUG) and short-form health survey-36 (SF-36) and short musculoskeletal function assessment (SFMA) questionnaires were administered. Results: Patients had significant weight loss and functional improvement. At 1 year mean weight loss was 48.5 kg and mean TGUG improvement was 3.1 s. SMFA and SF-36 also showed improvement in functional components with weight loss at 6 months and 1-year post surgery. Significant associations were observed between TGUG and SMFA measures at all time points. Final weight at 1 year post bariatric surgery was also significantly correlated with most functional outcomes and changes in these outcomes. Partial correlations controlling for age revealed additional associations between body weight and functional outcomes, especially at the 6-month visit. Conclusion: Our results suggest that significant rapid weight loss, such as that attained by bariatric surgery, acutely improves musculoskeletal function in morbidly obese patients. Additionally, for patients with musculoskeletal disease or injury, weight loss resulting from bariatric surgery may serve as an adjunct for improving global functional outcome, and enhancing the rehabilitation potential.

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Bariatric Surgery: Choosing the Optimal Procedure

Cited by 19 publications

References 43 publications

Nivel de proteína C reactiva en pacientes con obesidad mórbida antes y después de cirugía bariátrica

Nivel de proteína C reactiva en pacientes con obesidad mórbida antes y después de cirugía bariátrica

C-Reactive protein level in morbidly obese patients before and after bariatric surgery

Musculoskeletal function following bariatric surgery

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