Baricitnib: from rheumatoid arthritis to alopecia areata

Shaikh, Omer Ahmed; Shaikh, Gulrukh; Lone, Sadia Asghar

doi:10.47391/jpma.6898

Cited by 3 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Aplasia and hypoplasia were the most common ACoA variants with 24.1% ( n = 7) and 44.8% ( n = 13), respectively. This was similar to studies published by Prasad et al 6 and Shaikh and Sohail 9 who both recorded the ACoA as most anomalous in the anterior circulation.…”

Section: Discussionsupporting

confidence: 91%

“…The second approach entailed using a sample size comparative to that of similar studies. Similar studies were conducted by Maaly and Ismail 8 in an Egyptian population, Shaikh and Sohail 9 in an adult Pakistani population, and Saikia et al 5 in a northeastern Indian population comprising 180, 135, and 70 participants, respectively.…”

Section: Methodssupporting

confidence: 75%

“…The frequency of a complete CoW varies between populations ranging from 22.2% in an adult Pakistani population 9 to 46.7% in an Egyptian population. 8 Other frequencies obtained were 24.28% in a northeastern Indian population, 5 35.4% in a Nepalese population, 6 34.50% in a Nigerian population, 17 and 69.57% in a Malawian population.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Anatomical variations in the circle of Willis on magnetic resonance angiography in a south Trinidad population

Diljohn,

Rampersad,

Maharaj

et al. 2023

BJR|Open

View full text Add to dashboard Cite

Objectives This article seeks to determine the prevalence of a complete circle of Willis (CoW) and its common morphological variations in a south Trinidad population, while also investigating the influence of gender, age, and ethnicity on CoW morphology. Methods A prospective, descriptive, cross-sectional study was done on the magnetic resonance images for consecutive patients who had a brain MRI/magnetic resonance angiography at a tertiary health institution in south Trinidad between October 2019 and September 2020. Patients with significant cerebrovascular disease and/or a history of prior neurosurgical intervention were excluded. Results A complete CoW was seen in 24.3%, with more complete circles observed in younger participants (≤45 years) and Afro-Trinidadians. No gender predilection for a complete CoW was demonstrated. The most common variations in the anterior and posterior parts of the circle were a hypoplastic anterior communicating artery (8.6%, n = 13) and bilateral aplastic posterior communicating arteries (18.4%, n = 28), respectively. Conclusions Significant variations exist in the CoW of a south Trinidad population with a frequency of complete in 24.3%, and more complete circles in younger patients and Afro-Trinidadians. Gender did not influence CoW morphology. Advances in knowledge Structural abnormalities in the CoW may be linked to future incidence of cerebrovascular diseases and should therefore be communicated to the referring physician in the written radiology report. Knowledge of variant anatomy and its frequency for a particular populations is also required by neurosurgeons and neuro-interventional radiologists to help with preprocedural planning and to minimize complications.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Methodssupporting

confidence: 75%

See 1 more Smart Citation

Anatomical variations in the circle of Willis on magnetic resonance angiography in a south Trinidad population

Diljohn,

Rampersad,

Maharaj

et al. 2023

BJR|Open

View full text Add to dashboard Cite

show abstract

“…Wird dieser verhindert, zum Beispiel durch ein zervixnahes Myom, dann ist möglicherweise auch die Geburtsauslösung blockiert. Wenn also zum Beispiel bei 41 + 3 SSW das Köpfchen keinerlei Kontakt aufgenommen hat, muss dies als ungünstiges Zeichen ernst genommen werden [8].…”

Section: Fehlender Kontakt Des Köpfchens Zum Unteren Uterinsegmentunclassified

Die Betreuung im Geburtszeitraum – eine Herausforderung an Geduld, Sorgfalt und Kompetenz

Hildebrandt

2024

Hebamme

View full text Add to dashboard Cite

Der errechnete Geburtstermin markiert einen Tag, bis zu dem statistisch betrachtet nur knapp die Hälfte aller Kinder tatsächlich geboren wurden. Dennoch wird er häufig als eine Art „Ablaufdatum“ einer Schwangerschaft gesehen, mit dessen Überschreiten sie pathologisch wird – zu Unrecht. Ein möglicherweise falsch errechnetes Schwangerschaftsalter sowie individuelle Faktoren bei Mutter und Kind können diesen Zeitpunkt verschieben. Daher ist es treffender, von einem Geburtszeitraum zu sprechen. Dieser Leitfaden gibt Hebammen eine Handlungsanleitung für die Betreuung vor und während des Geburtszeitraums.

show abstract

“…2 3 The disorder is more common in India, Pakistan, and especially southeastern Iran, as well as in several other countries worldwide. 1 2 3 4 5 In a recent study, we found a prevalence of one per ∼0.2% for homozygotes and 3.5% for heterozygotes of FXIII deficiency in southeastern Iran, named Khash FXIII. 6 A wide spectrum of bleeding episodes has been reported in patients with severe FXIII deficiency.…”

mentioning

confidence: 95%

Novel Insights into Heterozygous Factor XIII Deficiency

Dorgalaleh¹

2023

Semin Thromb Hemost

View full text Add to dashboard Cite

The prevalence and clinical significance of heterozygous factor XIII (FXIII) deficiency has long been debated, with controversial reports emerging since 1988. In the absence of large epidemiologic studies, but based on a few studies, a prevalence of 1 per 1,000 to 5,000 is estimated. In southeastern Iran, a hotspot area for the disorder, a study of more than 3,500 individuals found an incidence of 3.5%. Between 1988 and 2023, a total of 308 individuals were found with heterozygous FXIII deficiency, of which molecular, laboratory, and clinical presentations were available for 207 individuals. A total of 49 variants were found in the F13A gene, most of which were missense (61.2%), followed by nonsense (12.2%) and small deletions (12.2%), most occurring in the catalytic domain (52.1%) of the FXIII-A protein and most frequently in exon 4 (17%) of the F13A gene. This pattern is relatively similar to homozygous (severe) FXIII deficiency. In general, heterozygous FXIII deficiency is an asymptomatic condition without spontaneous bleeding tendency, but it can lead to hemorrhagic complications in hemostatic challenges such as trauma, surgery, childbirth, and pregnancy. Postoperative bleeding, postpartum hemorrhage, and miscarriage are the most common clinical manifestations, while impaired wound healing has been rarely reported. Although some of these clinical manifestations can also be observed in the general population, they are more common in heterozygous FXIII deficiency. While studies of heterozygous FXIII deficiency conducted over the past 35 years have shed light on some of the ambiguities of this condition, further studies on a large number of heterozygotes are needed to answer the major questions related to heterozygous FXIII deficiency.

show abstract

Baricitnib: from rheumatoid arthritis to alopecia areata

Abstract: not needed for LTE as described by the author instructions of JPMA

Cited by 3 publications

References 0 publications

Anatomical variations in the circle of Willis on magnetic resonance angiography in a south Trinidad population

Anatomical variations in the circle of Willis on magnetic resonance angiography in a south Trinidad population

Die Betreuung im Geburtszeitraum – eine Herausforderung an Geduld, Sorgfalt und Kompetenz

Novel Insights into Heterozygous Factor XIII Deficiency

Contact Info

Product

Resources

About