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In recent years, gastric ulceration has been recognised as a common, possibly performance-limiting disease of adult horses. Here, we aim to provide the reader with a useful review of recent literature covering all aspects of equine gastric ulcer syndrome (EGUS) in adult horses. The anatomy and physiology of the stomach, with particular reference to secretion of acid and mucosal protective mechanisms, are reviewed, as are the differing theories relating to the aetiopathogenesis of gastric ulceration. We also explore the possible influence of various management factors on development of the disease. The prevalence of the disease in racehorses has been reported to be as high as 100%. In general, horses that are in active training for racing tend to have a prevalence of around 90%, whereas pleasure horses in full work have a reported prevalence of approximately 60%. Emerging diagnostic tests which could obviate the need for gastroscopy are introduced and current recommendations for treatment are summarised, focussing on proton pump inhibitors, in particular omeprazole, administered orally. The oral administration of omeprazole has been shown to be effective in both treating horses with gastric ulceration and at preventing re-occurrence whilst the horses are in training, provided that daily dosing is maintained.
In recent years, gastric ulceration has been recognised as a common, possibly performance-limiting disease of adult horses. Here, we aim to provide the reader with a useful review of recent literature covering all aspects of equine gastric ulcer syndrome (EGUS) in adult horses. The anatomy and physiology of the stomach, with particular reference to secretion of acid and mucosal protective mechanisms, are reviewed, as are the differing theories relating to the aetiopathogenesis of gastric ulceration. We also explore the possible influence of various management factors on development of the disease. The prevalence of the disease in racehorses has been reported to be as high as 100%. In general, horses that are in active training for racing tend to have a prevalence of around 90%, whereas pleasure horses in full work have a reported prevalence of approximately 60%. Emerging diagnostic tests which could obviate the need for gastroscopy are introduced and current recommendations for treatment are summarised, focussing on proton pump inhibitors, in particular omeprazole, administered orally. The oral administration of omeprazole has been shown to be effective in both treating horses with gastric ulceration and at preventing re-occurrence whilst the horses are in training, provided that daily dosing is maintained.
Bezdûková, B., P. Jahn, M. Vyskoãil, J. Plach˘: Prevalence of Equine Gastric Ulceration in Standardbred Racehorses in Czech Republic. Acta Vet. Brno 2005, 74: 59-65.The objective of our study was to determine an association between age, sex and prevalence and severity of gastric ulceration in Standardbred racehorses in training in Czech Republic. Alltogether 54 Standardbred racehorses were used in our study. History was taken and subsequently gastroscopy was performed in each horse. Mucosal ulceration was evaluated using grading system ranging from 0 (normal mucosa, no lesions) to 4 (diffuse ulceration of mucosa, loss of margo plicatus continuity, with or without haemorrhage). Correlation between age, sex and prevalence and severity of ulcers was statistically assessed.Prevalence of gastric ulceration in the group of horses examined was 62.96%. Twenty horses (37.04%) had physiological findings on gastric mucosa (ulcer score 0), 16 horses (29.6%) had mild changes of gastric mucosa (ulcer score 1), 14 horses (25.9%) had gastric ulcer score of grade 2 and 4 horses (7.4%) had gastric ulcer score of grade 3. None of the horses (0%) had signs of the most severe gastric ulceration (ulcer score 4). There was found neither association between age or sex and prevalence of ulcers nor association between age or sex and severity of gastric ulcers.From the results we conclude that gastric ulcers are common in Standardbred racehorses in Czech Republic. Prevalence and severity of gastric ulcer does not depend on age and sex of horses.
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