Barriers and Facilitators of Romanian HPV (Human Papillomavirus) Vaccination

Manolescu, Loredana Sabina Cornelia; Zugravu, Corina‐Aurelia; Zaharia, Corneliu; Dumitrescu, Anca; Prasacu, Irina; Radu, Mihaela Corina; Letiția, Goraneanu Draghici; Niţă, Irina; Cristache, Corina Marilena; Galeş, Laurenţia

doi:10.3390/vaccines10101722

Cited by 8 publications

(4 citation statements)

References 39 publications

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“…[48], as well as for reasons related to the parents' beliefs, attitudes and social prejudices. Poor participation in all vaccination campaigns was generated by deficient public health strategies-there were enough vaccine doses to ensure coverage of the targeted population, there was adequate diffusion in all areas and in locations that facilitated access (the vaccination campaigns were implemented in schools) and there were enough doctors to administer the vaccine [49]. The only reason for the failure of the vaccination programs remains the lack of adequate information campaigns addressing the lack of knowledge about the connection between HPV and cancer and the general lack of acknowledgement of the importance and benefits of HPV vaccination.…”

Section: Hpv Vaccination Program In Romaniamentioning

confidence: 99%

“…Given the fact that, in Romania, parental consent and an active request for the HPV vaccine is required for children under 18 years to be vaccinated, it is paramount to understand parents' profiles, beliefs and general acceptance of the vaccine in order to optimize vaccination and improve participation rates. The facilitators for parents to be willing to vaccinate their children against HPV include obtaining information from medical sources [49], female gender [49,50], urban settings [51,52], higher income status and higher educational level [53,54]. As with other vaccines, the physician's recommendations sway parental consent [55].…”

Section: Hpv Vaccination Program In Romaniamentioning

confidence: 99%

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Inequities in Screening and HPV Vaccination Programs and Their Impact on Cervical Cancer Statistics in Romania

Simion,

Rotaru,

Cirimbei

et al. 2023

Diagnostics

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(1) Introduction: A Romanian woman is diagnosed with cervical cancer every two hours; the country ranks second in Europe in terms of the mortality and incidence rate of this disease. This paper aims to identify the main reasons that have led to this situation, focusing on the measures taken by the Romanian Ministry of Health for the prevention of this type of cancer—national programs for cervical cancer screening and HPV vaccination. (2) Materials and methods: We performed a study based on the available secondary data from the National Statistics Institute, World Health Organization and Bucharest Institute of Oncology in order to assess the burden associated with cervical cancer and place it in the context of known global and European incidence and mortality rates, thus evaluating the importance of this health issue in Romania. The second component of our study was a cross-sectional study. Here, we used a 14-question questionnaire applied to the women participating in the National Screening Program for Cervical Cancer and aimed to evaluate the women’s level of knowledge about screening and HPV vaccination and their access cervical-cancer-specific healthcare services. (3) Results: The results of this research show that a high percentage of women postpone routine checks due to a lack of time and financial resources and indicate that a low level of knowledge about the disease and the specific preventive methods determines the low participation in screening and HPV vaccination programs implemented in Romania, contributing to the country’s cervical cancer situation. (4) Conclusions: The national programs have complicated procedures, are underfunded and do not motivate healthcare workers enough. This, combined with the lack of information for the eligible population, adds up to an extremely low number of women screened and vaccinated. Our conclusion is that the Romanian Ministry of Health must take immediate action by conducting major awareness campaigns, implementing measures to make the programs functional and ensuring coherent funding.

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Section: Hpv Vaccination Program In Romaniamentioning

confidence: 99%

Section: Hpv Vaccination Program In Romaniamentioning

confidence: 99%

Inequities in Screening and HPV Vaccination Programs and Their Impact on Cervical Cancer Statistics in Romania

Simion,

Rotaru,

Cirimbei

et al. 2023

Diagnostics

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“…Developing a preventive vaccination for herpes simplex virus types 1 and 2 (HSV-1 and 2) is a worldwide public health priority [ 46 , 47 ]. Vaccination is the most effective weapon that humanity holds [ 48 ].…”

Section: Vaccinesmentioning

confidence: 99%

Advances in Alpha Herpes Viruses Vaccines for Human

2023

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Alpha herpes simplex viruses are an important public health problem affecting all age groups. It can produce from common cold sores and chicken pox to severe conditions like encephalitis or newborn mortality. Although all three subtypes of alpha herpes viruses have a similar structure, the produced pathology differs, and at the same time, the available prevention measures, such as vaccination. While there is an available and efficient vaccine for the varicella-zoster virus, for herpes simplex virus 1 and 2, after multiple approaches from trivalent subunit vaccine to next-generation live-attenuated virus vaccines and bioinformatic studies, there is still no vaccine available. Although there are multiple failed approaches in present studies, there are also a few promising attempts; for example, the trivalent vaccine containing herpes simplex virus type 2 (HSV-2) glycoproteins C, D, and E (gC2, gD2, gE2) produced in baculovirus was able to protect guinea pigs against vaginal infection and proved to cross-protect against HSV-1. Another promising vaccine is the multivalent DNA vaccine, SL-V20, tested in a mouse model, which lowered the clinical signs of infection and produced efficient viral eradication against vaginal HSV-2. Promising approaches have emerged after the COVID-19 pandemic, and a possible nucleoside-modified mRNA vaccine could be the next step. All the approaches until now have not led to a successful vaccine that could be easy to administer and, at the same time, offer antibodies for a long period.

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“…In the past, several years after the HIV/AIDS pandemic had begun back in the 1990s, there was much reluctance in dental professionals toward working with and for PLWHA [ 21 ]. Despite the fact that prophylaxis is available for general infectious diseases and should be known by all healthcare workers [ 22 , 23 , 24 , 25 ], dental professionals may be exposed when working with PLWHA, and the risk of getting infected still exists even today. HIV pre-exposure and post-exposure prophylaxis methods are important when it comes to HIV/AIDS prevention.…”

Section: Introductionmentioning

confidence: 99%

Ageing People Living with HIV/AIDS, PLWHA; More Dental Challenges; the Romanian Dental Professional’s Point of View

Caministeanu

Manolescu

Malița

et al. 2023

Life

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Background: In Romania, HIV (human immunodeficiency virus) and AIDS (acquired immunodeficiency syndrome) were first acknowledged in 1989. Getting older with HIV/AIDS is now possible due to antiretroviral treatment, but it can bring dental problems due to HIV itself or to the reluctance of dental professionals to treat dental problems. Our study aims to assess the attitudes, knowledge, and practices of Romanian dental professionals regarding aging PLWHA. Methods: An analytical cross-sectional observational survey based on a self-administered questionnaire was conducted for Romanian dental professionals from October 2022 to January 2023. Results: The responders’ group profile was as follows: a mean age of 39.09 ± 0.36 years (limit: 19–75), a majority of 991 (90.01%) from urban dental offices, and 364 (33.06%) with more than twenty years’ experience. A total of 517 (46.95%) responders had an unprofessional attitude and declared that, if possible, they would avoid taking part in performing dental treatments for people living with HIV/AIDS (PLWHA). There were 89 (8.08%) dental professionals that refused to work with PLWHA. Only 363 (32.97%) had worked with one previously. The dental professionals in rural areas refused PLWHA more frequently: 20% (N = 22) of rural dental professionals vs. 6.76% (N = 67) of urban dental professionals refused to work with PLWHA (OR = 0.30; 95% CI: 0.16-.56). The logistic regression applied for the 1101 responders revealed after stepwise selection that the most influential factor for their refusal to work with PLWHA in our study group was being previously exposed to HIV during dental practice (OR = 14.45; 95% CI: 8.55- 24.42; p = 0.000). Conclusions: Dental educators and health care planners should promote the knowledge of prophylaxis and positive attitudes towards the treatment of PLWHA. Successful resolution of these concerns is time consuming and expensive but necessary if dentists are to satisfy their professional obligations to HIV/AIDS patients.

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Barriers and Facilitators of Romanian HPV (Human Papillomavirus) Vaccination

Cited by 8 publications

References 39 publications

Inequities in Screening and HPV Vaccination Programs and Their Impact on Cervical Cancer Statistics in Romania

Inequities in Screening and HPV Vaccination Programs and Their Impact on Cervical Cancer Statistics in Romania

Advances in Alpha Herpes Viruses Vaccines for Human

Ageing People Living with HIV/AIDS, PLWHA; More Dental Challenges; the Romanian Dental Professional’s Point of View

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