Barriers and facilitators to dissemination and adoption of precision medicine among Hispanics/Latinos

Canedo, Juan; Wilkins, Consuelo H.; Senft, Nicole; Romero, Araceli Romero; Bonnet, Kemberlee; Schlundt, David G.

doi:10.1186/s12889-020-08718-1

Cited by 26 publications

(20 citation statements)

References 48 publications

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“…Our work is consistent with previous qualitative research among patients considering precision medicine, in which patients knew little about the subject, but expressed worry about costs. 17 Studies have recently started to evaluate approaches to increase patient understanding and participation in precision medicine decisions, but much work remains to be done. 18,19 To address patient concerns regarding medico-legal implications of germline testing, providers would be well served by additional familiarity with legislation, such as the Genetic Information Nondiscrimination Act (GINA).…”

Section: Theme 6: Capacity For Organizational Changementioning

confidence: 99%

Barriers and facilitators of germline genetic evaluation for prostate cancer

Loeb

Nolasco

et al. 2021

The Prostate

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Background: Genetic counseling and germline testing have an increasingly important role for patients with prostate cancer (PCa); however, recent data suggests they are underutilized. Our objective was to perform a qualitative study of the barriers and facilitators of germline genetic evaluation among physicians who manage PCa.Methods: We conducted semi-structured interviews with medical oncologists, radiation oncologists, and urologists from different U.S. practice settings until thematic saturation was achieved at n = 14. The interview guide was based on the Tailored Implementation in Chronic Diseases Framework to identify key determinants of practice. Interview transcripts were independently coded by ≥2 investigators using a constant comparative method.Results: The decision to perform or refer for germline genetic evaluation is affected by factors at multiple levels. Although patient factors sometimes play a role, the dominant themes in the decision to conduct germline genetic evaluation were at the physician and organizational level. Physician knowledge, coordination of care, perceptions of the guidelines, and concerns about cost were most frequently discussed as the main factors affecting utilization of germline genetic evaluation.Conclusions: There are currently numerous barriers to implementation of germline genetic evaluation for PCa. Efforts to expand physician education, to develop tools to enhance genetics in practice, and to facilitate coordination of care surrounding genetic evaluation are important to promote guideline-concordant care.

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Section: Theme 6: Capacity For Organizational Changementioning

confidence: 99%

Barriers and facilitators of germline genetic evaluation for prostate cancer

Loeb

Nolasco

et al. 2021

The Prostate

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“…other studies have used similarly higher proportion of participant women in their focus groups. 31,32 This limitation also allows for the possibility of conducting further studies with a focus on male participants.…”

Section: Theme 3: Knowledge Of Prevention Campaigns In the Communitymentioning

confidence: 99%

Perceptions, awareness, and barriers to care regarding obesity and diabetes among Latinx in Miami and Escambia, Florida: a qualitative geographical comparative study

Martin

Obioha

Gaikwad

et al. 2022

Journal of Global Health Reports

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BackgroundThere are important racial and geographic disparities linked with obesity and diabetes in the USA. Latinx residing in rural areas face a unique combination of factors that can exacerbate existing healthcare disparities, increasing the prevalence of diabetes. MethodsQualitative study using focus groups was carried out between November 2014 and February 2015. The six focus groups were evenly split between Miami (Miami-Dade) and Pensacola (Escambia County) both in Florida. A total of 57 Latinx, 40 years and older, were recruited for a 60-minute session. Baseline demographic and clinical information were collected using a questionnaire before starting the focus group. Open-ended questions recorded participants' perceptions about obesity and diabetes and barriers to health care. Theme analysis was conducted for each question and across the groups. ResultsWhile most Hispanics understood that diabetes is a serious disease, neither those in Miami nor Escambia understood the difference between type 1 and 2 diabetes. Those in Miami had more knowledge about its long-term effects and expressed less language, communication and cultural barriers compared to those in Escambia. ConclusionsThere is a need to promote culture-appropriate health education programs geared towards raising awareness about diabetes in both communities but especially in rural communities.

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“…This combination is now widely covered across the Region and has evidenced significant cost benefits to healthcare systems and improved patient survival. 34 …”

Section: Personalized Medicinementioning

confidence: 99%

Recommendations for streamlining precision medicine in breast cancer care in Latin America

Alvarado‐Cabrero

Doimi

Ortega³

et al. 2021

Cancer Reports

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Background: The incidence of breast cancer (BC) in LMICs has increased by more than 20% within the last decade. In areas such as Latin America (LA), addressing BC at national levels evoke discussions surrounding fragmented care, limited resources, and regulatory barriers. Precision Medicine (PM), specifically companion diagnostics (CDx), links disease diagnosis and treatment for better patient outcomes. Thus, its application may aid in overcoming these barriers.Recent findings: A panel of LA experts in fields related to BC and PM were provided with a series of relevant questions to address prior to a multi-day conference. Within this conference, each narrative was edited by the entire group, through numerous rounds of discussion until a consensus was achieved. The panel proposes specific, realistic recommendations for implementing CDx in BC in LA and other LMIC regions.

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Barriers and facilitators to dissemination and adoption of precision medicine among Hispanics/Latinos

Cited by 26 publications

References 48 publications

Barriers and facilitators of germline genetic evaluation for prostate cancer

Barriers and facilitators of germline genetic evaluation for prostate cancer

Perceptions, awareness, and barriers to care regarding obesity and diabetes among Latinx in Miami and Escambia, Florida: a qualitative geographical comparative study

Recommendations for streamlining precision medicine in breast cancer care in Latin America

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