Barriers to colorectal cancer (CRS) screening in minority communities: inadequate knowledge of guidelines by physicians in training

GENNARELLI, M; JANDORF, L; CROMWELL, C; VALDIMARSDOTTIR, H; REDD, W; ITZKOWITZ, S

doi:10.1016/s0016-5085(01)83002-x

Cited by 15 publications

(17 citation statements)

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“…This fact accompanying by failure of physician recommendation were the most cited reasons for not having screening tests which shows that perception of CRC risk in general population and healthcare system plays an important role in the tendency of adults toward screening and prevention. This is consistently reported in several other papers too (10,11,14,16,19,20,23,24,27,31,32,(33)(34)(35). In a study by Omran and Ismail in Jordan, the most common sources of information about CRC screening were respectively family members, newspapers and magazines, television or radio and physicians (25).…”

Section: Discussionsupporting

confidence: 66%

Knowledge and perception toward colorectal cancer screening in east of Iran

Bidouei

Abdolhosseini

Jafarzadeh

et al. 2014

Int J Health Policy Manag

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Background: Colorectal Cancer (CRC) is the third most common cancer in Iran and its early detection is necessary. This study is based on perception of people in the east of Iran toward CRC screening. Methods: In a cross-sectional study, 1060 randomly selected individuals who referred to Razavi Hospital of Mashhad, Iran, between September the 1 st , 2012 and February the 28 th , 2013 as patients or their visitors involved in an interview to fill a questionnaire on CRC screening. Results: The participants' age ranged from 40 to 88 years (mean= 55). More than 90% had no knowledge of CRC and screening tests. The most cited reasons for not having screening tests were "did not have any problem" and "did not think it was needed". Although, older people had more knowledge of CRC (P= 0.033), there was no relationship between gender, health insurance status, family history of individuals and their knowledge about CRC (P> 0.050). Employment, education and higher income had positive effect on the perception of people toward CRC screening (P< 0.050). Conclusion: Lack of knowledge in people in lower socio-economical class with limited literacy is the most important barrier to CRC screening. As such, designing educational programs involving physicians and media is important to improve CRC screening rates.

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Section: Discussionsupporting

confidence: 66%

Knowledge and perception toward colorectal cancer screening in east of Iran

Bidouei

Abdolhosseini

Jafarzadeh

et al. 2014

Int J Health Policy Manag

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“…The current ACS guidelines for CRC screening includes: Fecal occult blood testing (FOBT) -Annually, Sigmoidoscopy every 5 years and colonoscopy once every 10 years, all starting at age 50 years (Levin, 2008). Knowledge, awareness, and beliefs of the doctors about CRC and its screening is a major factor, motivating general population to undergo screening (Sheih, 2005;Gennarelli, 2005). Considering the important role of the doctors (Specialists and Residents) in the screening activities, the present study was conducted to prospectively evaluate the knowledge and awareness about CRC and its screening programs among the doctors, working in different hospitals and primary health care centers in Al Ahssa region, Eastern province of Kingdom of Saudi Arabia.…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Awareness about Colorectal Cancer and Its Screening Guidelines among Doctors in Al Ahsa, Eastern Province, Kingdom of Saudi Arabia

Surendra

Hashir²,

Harbi

et al. 2016

GJHS

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Introduction: Cancer is a major public health problem. Worldwide, colorectal cancer (CRC) is a leading cause of deaths due to cancer in both men and women. Among, Saudi men, CRC is the most common malignancy while it is the third most common among Saudi women. Over, two decades the incidence and deaths due to CRC have been steadily increasing in Saudi Arabia. Regular and timely screening has the potential in reducing the incidence and deaths due to colorectal cancer. The present study is conducted to evaluate the knowledge and awareness about colorectal cancer and its screening among the doctors. Objectives:To measure the frequency of knowledge and awareness about colorectal cancer and its screening guidelines among doctors in Al-Ahssa. Methods:A questionnaire based survey of the doctors (Specialists & residents), working in different hospitals and primary health centers under the Ministry of Health in Al Ahssa region, Eastern province, KSA. Knowledge and awareness about colorectal cancer and its screening among the doctors is evaluated.Results: Over 80% of the doctors knew, screening reduces deaths due to CRC. Only 60% were aware about the risk factors and less than 50% knew the clinical features of CRC. About 60% doctors agreed Colonoscopy is gold standard screening test. While, less than 60% knew the ideal age to initiate screening and the actual interval of screening tests in the standard risk and high-risk population. Fewer than 25% doctors were aware about the American cancer society recommended screening guidelines. Majority of the doctors expressed keen interest to know and receive information about CRC and its screening guidelines.Conclusions: Regular and timely screening reduces deaths due to CRC. There is a need for improving knowledge and awareness of doctors about CRC and its screening. Awareness among the doctors improves uptake of screening by the general and high-risk population.

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“…In the United States, colorectal cancer has become the second most common cause of cancer-related deaths. 1) In 2008, an estimated 148810 cases of colorectal cancer will be diagnosed and 49960 people will die from this disease. 2) Although there have been advances in knowledge regarding the biology of the disease, the treatment options for advanced colon cancer are limited and chemotherapy is still one of the most important strategies to prevent its development.…”

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confidence: 99%

Asiatic Acid Induces Colon Cancer Cell Growth Inhibition and Apoptosis through Mitochondrial Death Cascade

Tang

Xia

Jung

et al. 2009

Biological & Pharmaceutical Bulletin

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Cancer is one of the leading causes of death in the world. The triterpenoid compound asiatic acid derived from the tropical medicinal plant Centella asiatica displays cytotoxic activity on fibroblast cells and several other kinds of cells. The present work studies asiatic acid-mediated growth inhibition of cancer cells and the underlying mechanism. Asiatic acid markedly inhibited cancer cell proliferation. Apoptosis of SW480 human colon cancer cells was induced by asiatic acid as shown by flow cytometry, DNA fragmentation and nuclear chromatin condensation experiments. Through increasing mitochondrial membrane permeability and cytochrome c release from mitochondria into cytosol, asiatic acid induced caspase-9 activity, which further activated caspase-3 and poly(ADP-ribose) polymerase cleavage resulting in irreversible apoptotic death in the tumor cells. Taken together, these results suggest that mitochondrial death apoptosis cascade plays very important roles in asiatic acid-induced cancer apoptosis.

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Barriers to colorectal cancer (CRS) screening in minority communities: inadequate knowledge of guidelines by physicians in training

Cited by 15 publications

References 0 publications

Knowledge and perception toward colorectal cancer screening in east of Iran

Knowledge and perception toward colorectal cancer screening in east of Iran

Knowledge and Awareness about Colorectal Cancer and Its Screening Guidelines among Doctors in Al Ahsa, Eastern Province, Kingdom of Saudi Arabia

Asiatic Acid Induces Colon Cancer Cell Growth Inhibition and Apoptosis through Mitochondrial Death Cascade

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