Barriers to Coronavirus Disease 19 vaccination in patients with obesity

Kizilkaya, Mehmet; Kilic, Sarah; Öncel, Deniz; Mamidanna, Swati; Daliparty, Vasudev Malik; Yılmaz, Serhan; Bozkurt, Mehmet Abdussamet; Sibic, Osman; Sayan, Mutlay

doi:10.1016/j.amjsurg.2022.08.021

Cited by 4 publications

(3 citation statements)

References 29 publications

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“…However, empirical evidence regarding the presence of pre-existing conditions as factors influencing vaccine uptake varies. For instance, in a study conducted by Kizilkaya et al, obese patients were observed to be more likely to be unvaccinated [ 56 ]. Another study reported a higher prevalence of unvaccinated individuals among those with chronic conditions [ 57 ].…”

Section: Discussionmentioning

confidence: 99%

Vaccine Uptake and Intentions: Insights from a Texas Survey on Factors Influencing COVID-19 Vaccination Decisions

Tiruneh,

Cuccaro,

Elliott

et al. 2024

Vaccines

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The effectiveness of COVID-19 vaccines depends on widespread vaccine uptake. Employing a telephone-administered weighted survey with 19,502 participants, we examined the determinants of COVID-19 vaccine acceptance among adults in Texas. We used multiple regression analysis with LASSO-selected variables to identify factors associated with COVID-19 vaccine uptake and intentions to receive the vaccine among the unvaccinated. The prevalence of unvaccinated individuals (22%) was higher among those aged 18–39, males, White respondents, English speakers, uninsured individuals, those facing financial challenges, and individuals expressing no concern about contracting the illness. In a fully adjusted regression model, higher odds of being unvaccinated were observed among males (aOR 1.11), the uninsured (aOR 1.38), smokers (aOR 1.56), and those facing financial struggles (aOR 1.62). Conversely, Asians, Blacks, and Hispanics were less likely to be unvaccinated compared to Whites. Among the unvaccinated, factors associated with stronger intent to receive the vaccine included age (over 65 years), Black and Hispanic ethnicity, and perceived risk of infection. Hispanic individuals, the uninsured, those covered by public insurance, and those facing financial challenges were more likely to encounter barriers to vaccine receipt. These findings underscore the importance of devising tailored strategies, emphasizing nuanced approaches that account for demographic, socioeconomic, and attitudinal factors in vaccine distribution and public health interventions.

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Section: Discussionmentioning

confidence: 99%

Vaccine Uptake and Intentions: Insights from a Texas Survey on Factors Influencing COVID-19 Vaccination Decisions

Tiruneh,

Cuccaro,

Elliott

et al. 2024

Vaccines

View full text Add to dashboard Cite

show abstract

“…The present study showed that the vaccination uptake was lowest among individuals with obesity in every age group, however, factors that may have caused the lower vaccine uptake in people with obesity were not known from the survey. Recent studies have reported that higher COVID-19 vaccine hesitancy was observed among individuals with obesity [ 50 , 51 ]. These studies showed that fear and skepticism towards the COVID-19 vaccination increased with weight and were associated with higher vaccine refusal.…”

Section: Discussionmentioning

confidence: 99%

Body Mass Index and Risk for COVID-19-Related Hospitalization in Adults Aged 50 and Older in Europe

Ohno

Dzúrová

2022

Nutrients

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Higher body mass index (BMI) has been associated with a higher risk for severe COVID-19 outcomes. The aim of this study was to investigate associations among BMI, underlying health conditions and hospital admission as well as the effects of COVID-19 vaccines in adults aged 50 years and older in Europe using data from the Survey of Health, Ageing and Retirement in Europe (SHARE) which was collected from June to August 2021, shortly after the second wave of the COVID-19 pandemic occurred in Europe. Survey data totalling 1936 individuals were used for statistical analyses to calculate the likelihood of hospitalization due to COVID-19 infection in relation to BMI, sociodemographic factors, comorbidities and COVID vaccination status. Approximately 16% of individuals testing positive for COVID-19 were hospitalized for COVID-19, and over 75% of these hospitalized individuals were either overweight or obese. The likelihood of hospitalization for individuals with obesity was approximately 1.5 times (CI [1.05–2.05]) higher than those with a healthy weight (BMI = 18.5–24.9 kg/m2) after adjusting for BMI, sex and age. After adjusting for sociodemographic factors, vaccination and comorbidities, the likelihood of hospitalization for individuals with obesity was 1.34 times higher than those with a healthy weight (CI [0.94–1.90]). Vaccine uptake was lowest in individuals with obesity (BMI ≥ 30 kg/m2) in all age groups. Individuals who had not received a vaccine were 1.8 times more likely to be hospitalized (CI [1.34–2.30]). Across European regions, obesity is associated with higher odds of hospitalization, and vaccination may be effective to reduce these odds for older adults.

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“…38 While government and media messaging targeting obesity may have contributed to more higher-weight people getting vaccinated, as was demonstrated in the English study, researchers have also critiqued COVID-19 messaging focused on obesity as potentially contributing to increased weight stigma. 39 Given significant COVID-19 vaccine hesitancy among those with obesity 40 and that weight bias is attributed to delays in preventive and acute care, 41 it is important to consider the potential impact of weight stigma in public health discourse regarding COVID-19. Townsend et al concluded that "weight stigma and its cumulative sequalae are a prevalent and distinct vulnerability that interacts with biologic and structural risks for worse COVID-19 outcomes," 42 highlighting the need to be attentive to issues of weight stigma when conducting public health outreach targeting higher-weight populations.…”

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confidence: 99%

How Should We Approach Body Size Diversity in Clinical Trials?

2023

AMA Journal of Ethics

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Regulatory and ethical considerations mandate that minorities affected by health disparities be included in research. Despite concerns about clinical outcomes for patients with obesity, clinical trials have reported few data about participation of and outcomes for such patients. This article examines the lack of body size diversity in clinical research participants and reviews the evidence and ethical arguments for including larger-bodied patients. Drawing on examples of improved gender diversification of trial participants, this article suggests that similar benefits would be likely from inclusion of body diversity. Diversity in Clinical TrialsClinical trials have historically overrepresented White male participants and underrepresented children and older adults, women, gender and sexually diverse people, and people of color. 1 Given the higher burden of disease among disadvantaged minorities, 1,2,3 their lack of representative inclusion in trials threatens to exacerbate health disparities. 4 Continued disparities in cardiovascular health demonstrate this phenomenon, as women and people of color continue to be underrepresented in clinical trials and thus benefit less from research advances. 5,6

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Barriers to Coronavirus Disease 19 vaccination in patients with obesity

Cited by 4 publications

References 29 publications

Vaccine Uptake and Intentions: Insights from a Texas Survey on Factors Influencing COVID-19 Vaccination Decisions

Vaccine Uptake and Intentions: Insights from a Texas Survey on Factors Influencing COVID-19 Vaccination Decisions

Body Mass Index and Risk for COVID-19-Related Hospitalization in Adults Aged 50 and Older in Europe

How Should We Approach Body Size Diversity in Clinical Trials?

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