“…While previous studies [7] , [12] , [13] have identified important and modifiable barriers to CPR initiation and/or continuation, they have overlooked the potential effect modification and confounding of different barriers and case characteristics. Here, we build on a previous study of emergency ambulance calls 10 where we identified eight barriers to immediate B-CPR initiation and continuation until the arrival of EMS: (1) perceived inappropriateness of B-CPR, (2) emotional distress, (3) caller reluctance, (4) bystander physical limitations, (5) patient access, (6) caller leaving the scene, (7) communication failure and (8) caller distractions. We previously found that cases had multiple barriers to CPR initiation and/or continuation co-occurring within the call, and therefore the aim of this study was to estimate the independent effects of each of the eight different barriers on caller initiation and continuation of CPR, after adjusting for case characteristics.…”