Publication metrics have become crucial to measure the productivity and impact of individuals and organizations for highlighting their influence upon the knowledge world. This study aims to present a bibliometric analysis of the top two percent highly cited Library and Information Science (LIS) researchers in the Stanford University list of the top two percent researchers of various disciplines published in 2021. We have used the bibliometric method to analyze 254 highly cited LIS researchers. The findings show male dominance and female underrepresentation in LIS research. Leydesdorff, Loet is the most highly cited researcher of the LIS field. The Amsterdam School of Communications Research, Netherlands, is the most highly cited organization of LIS based on the highly cited researchers affiliated with it. The majority of LIS researchers belong to USA and UK. There is a meager contribution of Asian, Australian, and African countries producing highly cited LIS researchers. Highly cited LIS researchers are more familiar with publishing research in information retrieval, information seeking, and bibliometrics. Positions of researchers at different ranks by different measures depict their productivity, impact, h- index, and a composite score. A strong correlation exists between total publications and total citations. The study, in its nature, is unique and will provide an insight for young and emerging researchers for selection of research direction, persons for research collaboration, and a motivation to invest more efforts for impactful research.