Basal cell adenoma of the parotid gland: Cytological diagnosis of an uncommon tumor

Bhat, Amoolya; Rao, M Srinivasa; Geethamani, V; Shetty, Archana

doi:10.4103/0973-029x.157211

Cited by 12 publications

(25 citation statements)

References 6 publications

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“…However, as previously stated, due to therapeutic and prognostic implications, the most important entities that must be differentiated from BCA in a FNAC procedure are basal cell adenocarcinoma and adenoid cystic carcinoma [2].…”

Section: Discussionmentioning

confidence: 99%

“…Canalicular adenoma should be kept in mind for its cytological features even if it occurs almost exclusively on the upper lip: it is characterized by small, regular cells and nuclei arranged in a trabecular or tubular pattern [2].…”

Section: Discussionmentioning

confidence: 99%

“…The majority of them are benign, and approximately 80% originate in the parotid gland. Basal cell adenoma (BCA) is an uncommon benign salivary gland tumor accounting for 1-2% of all salivary gland epithelial tumors [2,3]. It affects most frequently adult patients over 50 years of age with slight female prevalence.…”

Section: Introductionmentioning

confidence: 99%

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Potential Difficulties in Cytological Approach of Basal Cell Adenoma of Salivary Glands: The Experience of a Single Institution

Nicola¹,

Onorati²,

Lancia³

et al. 2018

Acta Cytologica

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Objective: Basal cell adenoma (BCA) is an uncommon benign epithelial neoplasm of salivary glands, which was first described by Kleinsasser and Klein in 1967 and which derives its name from the monomorphic basaloid appearance of tumor cells. This tumor represents 1–2% of all salivary gland epithelial tumors; the most common site of occurrence is the parotid gland. It usually arises in adults over 50 years of age with slight female prevalence. Study Design: We analyzed 5 cases of parotid lesions investigated by fine needle aspiration cytology at a single institution between 2002 and 2018. Results: Our series was composed by 3 women and 2 men with a mean age of 62 years. The most important cytological criteria we observed were cohesive sharp-angled clusters of regular basaloid cells, palisaded by p63-positive myoepithelial cells, and bordered by basement membrane-like hyaline membrane in the absence of a myxochondroid stroma. Overall features were consistent with the diagnosis of BCA. Conclusions: Our aim is to highlight the cytological features of these rare lesions improving the awareness of cytological pitfalls of salivary gland basaloid neoplasms. Moreover, the goal of this paper is to add to the literature 5 additional cases of these unusual tumors.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Potential Difficulties in Cytological Approach of Basal Cell Adenoma of Salivary Glands: The Experience of a Single Institution

Nicola¹,

Onorati²,

Lancia³

et al. 2018

Acta Cytologica

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“…Cytologically, sheets of small basaloid cells containing oval nuclei with fine chromatin that are usually devoid of prominent nucleoli are seen [6,7]. However, histopathologic confirmation of basal cell adenoma is necessary in order to exclude potential benign and malignant mimickers, including basal cell adenocarcinoma, canalicular adenoma, cellular pleomorphic adenoma, and the solid variant of adenoid cystic carcinoma [8]. Histologically, this tumor type is composed of nests of uniform basaloid cells, often displaying peripheral palisading, separated by a collagenous stroma [5,8].…”

Section: Introductionmentioning

confidence: 99%

“…However, histopathologic confirmation of basal cell adenoma is necessary in order to exclude potential benign and malignant mimickers, including basal cell adenocarcinoma, canalicular adenoma, cellular pleomorphic adenoma, and the solid variant of adenoid cystic carcinoma [8]. Histologically, this tumor type is composed of nests of uniform basaloid cells, often displaying peripheral palisading, separated by a collagenous stroma [5,8]. The membranous variant is further distinguished by the presence of prominent, hyalinized basement membrane-like material [5].…”

Section: Introductionmentioning

confidence: 99%

Synchronous Ipsilateral Parotid Tumors with Cytologic–Histologic Correlation

Gvozdjan

Groth

Patel

et al. 2015

Head and Neck Pathol

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Synchronous ipsilateral tumor formation within a major salivary gland is a very rare event. In this case, a 54-year-old female tobacco smoker presented with a slowly enlarging left parotid gland. Computed tomography of the neck demonstrated a solid mass superficial to a cystic mass in the deep lobe of the gland. Ultrasound-guided fine needle aspiration yielded oncocytic cells, lymphoid cells, and granular debris along with rare cohesive groups of basaloid cells. Parotidectomy was performed, and the resected gland was found to contain two adjacent but distinct masses. One mass, a predominantly solid, well-circumscribed lesion composed of ribbons of double-layered oncocytic cells and a lymphoid stroma with germinal center formation, was a Warthin tumor. The other mass, a predominantly cystic lesion composed of cords and nests of basaloid cells with associated deposits of basement membrane-like material, was a basal cell adenoma of the membranous type. To our knowledge, this is the first reported case of synchronous Warthin tumor and basal cell adenoma of the parotid gland with cytologic-histologic correlation attributable to each tumor.

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