Basal Cell Carcinoma Arising in a Cleft Lip Repair Scar

Wright, Mandy Warthan; McCarthy, Rebecca A.; Kelly, Erica; Wright, Steve; Wagner, Richard F.

doi:10.1097/00042728-200102000-00020

Cited by 3 publications

(3 citation statements)

References 13 publications

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“…There is scant data on possible exacerbating factors, which include trauma or ultraviolet radiation, both of which may be relevant because Marjolin ulcer is usually located on the extremities, the scalp and neck (20). Other less common anatomical sites, such as the nose, the eyelids and the lip have also been reported in the literature (21–23).…”

Section: Discussionmentioning

confidence: 99%

Marjolin ulcer: an overlooked entity

Pavlovic

Wiley

Guzman

et al. 2011

International Wound Journal

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Marjolin ulcer is a well-defined, but uncommon malignant ulcer that occurs in chronic wounds and cutaneous scars. Jean-Nicolas Marjolin was credited with describing this phenomenon in 1828. This entity is frequently overlooked and therefore inadequately treated leading to a poor prognosis. The malignant transformation of an ulcer is most commonly associated with burn scars, but has been reported in many other types of chronic, non healing wounds such as traumatic wounds, venous stasis and chronic pressure ulcers, fistulas, lacerations and leprosy ulcers. Development of malignancy tends to be slow with an average time of approximately 25 years. Various theories concerning pathogenesis of Marjolin ulcer have been proposed. Well-differentiated squamous cell carcinoma (SCC) is the most common histological type of Marjolin ulcer. Biopsy with histopathologic interpretation remains the gold standard for the diagnosis, with radical surgical excision being the treatment of choice. A high index of suspicion should be held by any health care provider when evaluating a chronic, non healing wound. This is a case report of a Marjolin ulcer arising on the left buttock of a patient with a long-standing history of a traumatic wound.

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Section: Discussionmentioning

confidence: 99%

Marjolin ulcer: an overlooked entity

Pavlovic

Wiley

Guzman

et al. 2011

International Wound Journal

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“…BCC arising in surgical scars is exceedingly rare, with only 11 prior cases reported (Table 1). 5–14 They have occurred in patients aged 41 to 69, and the latency period ranges from 9 months to 67 years after the original surgery. BCCs are more commonly reported in vaccination sites and burn scars.…”

Section: Discussionmentioning

confidence: 99%

A Case of Basal Cell Carcinoma Arising in Bilateral Mastoidectomy Scars

Soden

Fife

Miller

2009

Dermatologic Surgery

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“…Among the reconstruction techniques using autologous bone, the flap positioned subcutaneously in the abdominal cavity [2,20,23,38] requires a second surgical wound. This aspect, seemingly marginal, should not be underestimated because the onset of benign [9,18,32] or malignant [13,16,21,30,31,34,35,39] primary tumours from the surgical abdominal or thoracic scar is well-documented, both many years after surgery for benign lesions and after a few months for malignant ones. On the other hand, if the bone flap is kept in the subgaleal space [12,19,25] there may be undesired subcutaneous blood collections, but mainly a smaller skin surface available for brain swelling, since it is already employed in containing the craniotomy flap.…”

Section: Discussionmentioning

confidence: 99%