2013
DOI: 10.3109/09546634.2012.756572
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Basal cell carcinoma margin delineation: is curettage useful? A surgical and histological study

Abstract: Basal cell carcinoma (BCC) is the most common variety of non-melanoma skin cancer. Treatment modalities include cryotherapy, topical imiquimod 5% cream, photodynamic therapy, electrodessication and curettage, classic surgical excision, Mohs surgery, and radiotherapy. Surgical treatments are regarded as the most effective, but, in some cases, may produce poor cosmetic outcomes. Delineating tumor margins as much as possible is important in order to limit broad surgical excisions. Preoperative curettage is a surg… Show more

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Cited by 5 publications
(7 citation statements)
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“…Superficial and nodular basal cell carcinomas (BCCs) are best suited to defining tumor extent via curettage, whereas infiltrative, morpheaform, and micronodular BCCs are surrounded by dense collagen, and the extent of the tumor cannot be defined by curettage of tumor and stroma. 44,45 The same is true for desmoplastic squamous carcinoma and for tumors with perineural invasion, which may extend far beyond the clinically evident tumor margins.…”
Section: Basal Cell Carcinoma/squamous Cell Carcinomamentioning
confidence: 94%
“…Superficial and nodular basal cell carcinomas (BCCs) are best suited to defining tumor extent via curettage, whereas infiltrative, morpheaform, and micronodular BCCs are surrounded by dense collagen, and the extent of the tumor cannot be defined by curettage of tumor and stroma. 44,45 The same is true for desmoplastic squamous carcinoma and for tumors with perineural invasion, which may extend far beyond the clinically evident tumor margins.…”
Section: Basal Cell Carcinoma/squamous Cell Carcinomamentioning
confidence: 94%
“…To minimize the possibility of recurrences, the practician needs to remove 5 mm of the surrounding tissue with normal appearance [125]. This technique has been recommended for skin preparation since it delineates well the tumour [126], it is effective, acceptable, and quite inexpensive [127]. This gentle removal is often used for superficial basal cell carcinoma (sBCC) treatment and consists of scraping crust and scale [128].…”
Section: Stratum Corneum Removalmentioning
confidence: 99%
“…Curettage increased PpIX fluorescence [129] and according to [130] MAL-PDT with prior curettage was a promising method for the treatment of BCC with a clearance rate of 91% for sBCC (131 lesions treated), 93% for thin nBCC (82 lesions) and 86% for thick nBCC (86 lesions treated). Cosmetic out comes were excellent (i.e lesion area not visible) and recurrence rate after ALA-PDT with prior curettage was low which make it a good skin pretreatment method [126,130]. Nevertheless some authors report that curettage may damage surrounding healthy tissue and cause pain for patients [126,129].…”
Section: Stratum Corneum Removalmentioning
confidence: 99%
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“…It derives from the cells of the epidermal basal layer either interfollicular or of the hair follicle [1]. For the vast majority of the neoplasms, surgical excision with free margins is both diagnostic and therapeutic [2]. For a very small proportion of patients, with higher risk of recurrence, the preferred surgical technique is Mohs micrographic surgery [3-6].…”
Section: Introductionmentioning
confidence: 99%